|
rs110402
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Depressive episode, unspecified
|
|
0.010 |
GeneticVariation |
BEFREE |
rs110402, in CRHR1 gene, was associated with an increased risk to present a seasonal pattern and an early age of onset of the first depressive episode.
|
17467808 |
2007 |
|
rs1876831
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
heavy drinking
|
|
0.010 |
GeneticVariation |
BEFREE |
Adolescents homozygous for the C allele of rs1876831 drank higher maximum amounts of alcohol per occasion and had greater lifetime rates of heavy drinking in relation to negative life events than individuals carrying the T allele.
|
17597588 |
2008 |
|
rs4792887
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Post-Traumatic Stress Disorder
|
|
0.010 |
GeneticVariation |
BEFREE |
After correction for multiple testing, rs12938031 and rs4792887 remained associated with post-hurricane PTSD symptoms.
|
24077033 |
2013 |
|
rs110402
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Alcohol Use Disorder
|
|
0.010 |
GeneticVariation |
BEFREE |
An interaction of CRHR1 rs110402 and CRHBP rs3811939 predicts high risk of comorbid AUD in schizophrenic patients (odds ratio = 2.27; 95% confidence interval, 1.56-3.30; P < .001) as well as psychiatric disease controls (odds ratio = 4.02; 95% confidence interval, 0.95-17.05; P = .06) and leads to the highest CRHR1/CRHBP messenger RNA ratio (P = .02; dysbalanced stress axis).
|
21810631 |
2011 |
|
rs110402
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Mental disorders
|
|
0.020 |
GeneticVariation |
BEFREE |
An interaction of CRHR1 rs110402 and CRHBP rs3811939 predicts high risk of comorbid AUD in schizophrenic patients (odds ratio = 2.27; 95% confidence interval, 1.56-3.30; P < .001) as well as psychiatric disease controls (odds ratio = 4.02; 95% confidence interval, 0.95-17.05; P = .06) and leads to the highest CRHR1/CRHBP messenger RNA ratio (P = .02; dysbalanced stress axis).
|
21810631 |
2011 |
|
rs1876829
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Waist-Hip Ratio
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Association of Genetic Variants Related to Gluteofemoral vs Abdominal Fat Distribution With Type 2 Diabetes, Coronary Disease, and Cardiovascular Risk Factors.
|
30575882 |
2018 |
|
rs16940655
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Mood Disorders
|
|
0.010 |
GeneticVariation |
BEFREE |
By single marker analysis we have found an association of rs28536160 of AVPR1b and rs4076452 and rs16940655 of CRHR1 with mood disorders (P=0.036, 0.0013, and 0.003, respectively).
|
23962971 |
2013 |
|
rs12150390
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Parkinson Disease
|
|
0.700 |
GeneticVariation |
GWASDB |
Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.
|
22438815 |
2012 |
|
rs1396862
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Parkinson Disease
|
|
0.700 |
GeneticVariation |
GWASDB |
Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.
|
22438815 |
2012 |
|
rs16940665
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Parkinson Disease
|
|
0.700 |
GeneticVariation |
GWASDB |
Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.
|
22438815 |
2012 |
|
rs17763086
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Parkinson Disease
|
|
0.700 |
GeneticVariation |
GWASDB |
Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.
|
22438815 |
2012 |
|
rs1876828
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Parkinson Disease
|
|
0.700 |
GeneticVariation |
GWASDB |
Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.
|
22438815 |
2012 |
|
rs1912151
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Parkinson Disease
|
|
0.700 |
GeneticVariation |
GWASDB |
Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.
|
22438815 |
2012 |
|
rs4525537
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Parkinson Disease
|
|
0.700 |
GeneticVariation |
GWASDB |
Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.
|
22438815 |
2012 |
|
rs4640231
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Parkinson Disease
|
|
0.700 |
GeneticVariation |
GWASDB |
Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.
|
22438815 |
2012 |
|
rs878886
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Parkinson Disease
|
|
0.700 |
GeneticVariation |
GWASDB |
Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.
|
22438815 |
2012 |
|
rs878887
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Parkinson Disease
|
|
0.700 |
GeneticVariation |
GWASDB |
Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.
|
22438815 |
2012 |
|
rs878888
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Parkinson Disease
|
|
0.700 |
GeneticVariation |
GWASDB |
Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.
|
22438815 |
2012 |
|
rs242939
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Major Depressive Disorder
|
|
0.030 |
GeneticVariation |
BEFREE |
CRHR1 gene (rs1876828, rs242939 and rs242941) and BDNF gene (rs6265) were identified in the samples of patients diagnosed with recurrent MDD and matched controls.
|
22194899 |
2011 |
|
rs242941
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Major Depressive Disorder
|
|
0.030 |
GeneticVariation |
BEFREE |
CRHR1 gene (rs1876828, rs242939 and rs242941) and BDNF gene (rs6265) were identified in the samples of patients diagnosed with recurrent MDD and matched controls.
|
22194899 |
2011 |
|
rs778136105
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Asthma
|
|
0.010 |
GeneticVariation |
BEFREE |
Early studies suggest that bronchodilator reversibility and asthma worsening in patients on continuous short-acting and long-acting beta-agonists are related to the Gly16Arg genotype for the ADRB2.
|
19077707 |
2009 |
|
rs1876828
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Asthma
|
|
0.010 |
GeneticVariation |
BEFREE |
Eighty-two children (56 boys/26 girls, mean age 9.6 ± 3.2 years) with moderate-severe asthma exacerbation were genotyped for eight single-nucleotide polymorphisms that were a priori associated with ICS response in chronic asthma treatment: glucocorticosteroid receptor (NR3C1) rs41423247; corticotrophin-releasing hormone receptor1 (CRHR1) rs242939, rs242941, and rs1876828; T-box 21 (TBX21) rs2240017; glucocorticoid-induced transcript 1 (GLCCl1); and T gene rs3099266 and rs2305089.
|
27003716 |
2016 |
|
rs242939
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Asthma
|
|
0.010 |
GeneticVariation |
BEFREE |
Eighty-two children (56 boys/26 girls, mean age 9.6 ± 3.2 years) with moderate-severe asthma exacerbation were genotyped for eight single-nucleotide polymorphisms that were a priori associated with ICS response in chronic asthma treatment: glucocorticosteroid receptor (NR3C1) rs41423247; corticotrophin-releasing hormone receptor1 (CRHR1) rs242939, rs242941, and rs1876828; T-box 21 (TBX21) rs2240017; glucocorticoid-induced transcript 1 (GLCCl1); and T gene rs3099266 and rs2305089.
|
27003716 |
2016 |
|
rs242941
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Asthma
|
|
0.010 |
GeneticVariation |
BEFREE |
Eighty-two children (56 boys/26 girls, mean age 9.6 ± 3.2 years) with moderate-severe asthma exacerbation were genotyped for eight single-nucleotide polymorphisms that were a priori associated with ICS response in chronic asthma treatment: glucocorticosteroid receptor (NR3C1) rs41423247; corticotrophin-releasing hormone receptor1 (CRHR1) rs242939, rs242941, and rs1876828; T-box 21 (TBX21) rs2240017; glucocorticoid-induced transcript 1 (GLCCl1); and T gene rs3099266 and rs2305089.
|
27003716 |
2016 |
|
rs12944712
|
CRHR1;LINC02210-CRHR1
|
child abuse behavior
|
|
0.010 |
GeneticVariation |
BEFREE |
FKBP5 (rs1360780) and CRHR1 (rs12944712) polymorphisms significantly interacted with child abuse and adult stress to predict increases in physical health ailments over 3 years.
|
24099078 |
2014 |