Disease: Multiple Sclerosis ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs7200786
rs7200786
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0026769
Disease:
Multiple Sclerosis 		A 0.800 GeneticVariation GWASDB Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. 21833088 2011
dbSNP: rs7200786
rs7200786
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0026769
Disease:
Multiple Sclerosis 		A 0.800 GeneticVariation GWASCAT Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. 21833088 2011
dbSNP: rs11865121
rs11865121
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0026769
Disease:
Multiple Sclerosis 		C 0.800 GeneticVariation GWASCAT Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. 19525953 2009
dbSNP: rs11865121
rs11865121
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0026769
Disease:
Multiple Sclerosis 		C 0.800 GeneticVariation GWASDB Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. 19525953 2009
dbSNP: rs12708716
rs12708716
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0026769
Disease:
Multiple Sclerosis 		0.710 GeneticVariation GWASDB Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. 21833088 2011
dbSNP: rs12708716
rs12708716
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0026769
Disease:
Multiple Sclerosis 		0.710 GeneticVariation BEFREE In combined analyses, SNP rs12708716 gave the strongest association signal in MS (P=5.3 x 10⁻⁸, odds ratio 1.18, 95% confidence interval=1.11-1.25), and was found to be superior to the other SNP associations in conditional logistic regression analyses. 21179112 2011
dbSNP: rs6498160
rs6498160
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0026769
Disease:
Multiple Sclerosis 		T 0.700 GeneticVariation GWASCAT Overexpression of the Cytokine BAFF and Autoimmunity Risk. 28445677 2017
dbSNP: rs6498168
rs6498168
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0026769
Disease:
Multiple Sclerosis 		T 0.700 GeneticVariation GWASCAT Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation. 27386562 2016
dbSNP: rs12927355
rs12927355
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0026769
Disease:
Multiple Sclerosis 		G 0.700 GeneticVariation GWASCAT Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. 24076602 2013
dbSNP: rs11860603
rs11860603
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0026769
Disease:
Multiple Sclerosis 		0.700 GeneticVariation GWASDB Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. 19525953 2009
dbSNP: rs7184083
rs7184083
Entrez Id: 23274;105371081
Gene Symbol: CLEC16A;LOC105371081
CLEC16A;LOC105371081
CUI: C0026769
Disease:
Multiple Sclerosis 		0.700 GeneticVariation GWASDB Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. 19525953 2009
dbSNP: rs6498169
rs6498169
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0026769
Disease:
Multiple Sclerosis 		0.030 GeneticVariation BEFREE Association of SNPs rs6498169 and rs10984447 with multiple sclerosis in Saudi patients: a model of the usefulness of familial aggregates in identifying genetic linkage in a multifactorial disease. 22492128 2012
dbSNP: rs6498169
rs6498169
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0026769
Disease:
Multiple Sclerosis 		0.030 GeneticVariation BEFREE The described association of rs6498169 with MS was replicated in MS and RA cohorts. 19221398 2010
dbSNP: rs6498169
rs6498169
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0026769
Disease:
Multiple Sclerosis 		0.030 GeneticVariation BEFREE Independent genome-wide association studies highlighted the function of CLEC16A/KIAA0350 polymorphisms modifying the risk to either multiple sclerosis (rs6498169) or type 1 diabetes (rs2903692). 19337309 2009
dbSNP: rs725613
rs725613
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0026769
Disease:
Multiple Sclerosis 		0.020 GeneticVariation BEFREE We could replicate the finding for SNP rs725613 and were able to show for the first time the association of rs2041670, rs2080272 and rs998592 with MS. 20849399 2011
dbSNP: rs725613
rs725613
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0026769
Disease:
Multiple Sclerosis 		0.020 GeneticVariation BEFREE In these Sardinian samples, allele A of rs725613 is positively associated not only with T1D (odds ratio=1.15, P one-tail=5.1 x 10(-3)) but also, and with a comparable effect size, with MS (odds ratio=1.21, P one-tail 6.7 x 10(-5)). 18946483 2009
dbSNP: rs8056098
rs8056098
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0026769
Disease:
Multiple Sclerosis 		0.010 GeneticVariation BEFREE Three SNPs linked to MS clinical severity showed a significant association between the genotype and either the proportion of active lesions (rs2234978/FAS and rs11957313/KCNIP1) or the proportion of mixed active/inactive lesions (rs8056098/CLEC16A). 31228212 2020
dbSNP: rs2041670
rs2041670
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0026769
Disease:
Multiple Sclerosis 		0.010 GeneticVariation BEFREE We could replicate the finding for SNP rs725613 and were able to show for the first time the association of rs2041670, rs2080272 and rs998592 with MS. 20849399 2011
dbSNP: rs2080272
rs2080272
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0026769
Disease:
Multiple Sclerosis 		0.010 GeneticVariation BEFREE We could replicate the finding for SNP rs725613 and were able to show for the first time the association of rs2041670, rs2080272 and rs998592 with MS. 20849399 2011
dbSNP: rs998592
rs998592
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0026769
Disease:
Multiple Sclerosis 		0.010 GeneticVariation BEFREE We could replicate the finding for SNP rs725613 and were able to show for the first time the association of rs2041670, rs2080272 and rs998592 with MS. 20849399 2011
dbSNP: rs1465201414
rs1465201414
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0026769
Disease:
Multiple Sclerosis 		0.010 GeneticVariation BEFREE Rs4774 (missense +1614G/C; G500A) was associated with MS (P = 4.9 x 10(-3)), particularly in DRB1*1501 +individuals (P = 1 x 10(-4)). 20211854 2010
dbSNP: rs2903692
rs2903692
Entrez Id: 23274
Gene Symbol: CLEC16A
CLEC16A
CUI: C0026769
Disease:
Multiple Sclerosis 		0.010 GeneticVariation BEFREE Independent genome-wide association studies highlighted the function of CLEC16A/KIAA0350 polymorphisms modifying the risk to either multiple sclerosis (rs6498169) or type 1 diabetes (rs2903692). 19337309 2009