HNF1A-AS1, HNF1A antisense RNA 1, 283460

N. diseases: 70; N. variants: 31
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1169288
rs1169288
Entrez Id: 6927;283460
Gene Symbol: HNF1A;HNF1A-AS1
HNF1A;HNF1A-AS1
CUI: C0202117
Disease:
Low density lipoprotein cholesterol measurement 		C 0.800 GeneticVariation GWASDB Discovery and refinement of loci associated with lipid levels. 24097068 2013
dbSNP: rs1169288
rs1169288
Entrez Id: 6927;283460
Gene Symbol: HNF1A;HNF1A-AS1
HNF1A;HNF1A-AS1
CUI: C1445957
Disease:
Serum total cholesterol measurement 		C 0.800 GeneticVariation GWASCAT Discovery and refinement of loci associated with lipid levels. 24097068 2013
dbSNP: rs2251468
rs2251468
Entrez Id: 283460
Gene Symbol: HNF1A-AS1
HNF1A-AS1
CUI: C2242817
Disease:
Homocysteine measurement 		A 0.800 GeneticVariation GWASCAT Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease. 23824729 2013
dbSNP: rs2251468
rs2251468
Entrez Id: 283460
Gene Symbol: HNF1A-AS1
HNF1A-AS1
CUI: C2242817
Disease:
Homocysteine measurement 		A 0.800 GeneticVariation GWASDB Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease. 23824729 2013
dbSNP: rs2650000
rs2650000
Entrez Id: 283460
Gene Symbol: HNF1A-AS1
HNF1A-AS1
CUI: C0201657
Disease:
C-reactive protein measurement 		C 0.800 GeneticVariation GWASDB Are C-reactive protein associated genetic variants associated with serum levels and retinal markers of microvascular pathology in Asian populations from Singapore? 23844046 2013
dbSNP: rs7305618
rs7305618
Entrez Id: 283460
Gene Symbol: HNF1A-AS1
HNF1A-AS1
CUI: C0201657
Disease:
C-reactive protein measurement 		T 0.800 GeneticVariation GWASDB Are C-reactive protein associated genetic variants associated with serum levels and retinal markers of microvascular pathology in Asian populations from Singapore? 23844046 2013
dbSNP: rs7953249
rs7953249
Entrez Id: 283460
Gene Symbol: HNF1A-AS1
HNF1A-AS1
CUI: C0201657
Disease:
C-reactive protein measurement 		G 0.800 GeneticVariation GWASDB Are C-reactive protein associated genetic variants associated with serum levels and retinal markers of microvascular pathology in Asian populations from Singapore? 23844046 2013
dbSNP: rs1169288
rs1169288
Entrez Id: 6927;283460
Gene Symbol: HNF1A;HNF1A-AS1
HNF1A;HNF1A-AS1
CUI: C1278049
Disease:
Serum gamma-glutamyl transferase measurement 		G 0.800 GeneticVariation GWASCAT Loci affecting gamma-glutamyl transferase in adults and adolescents show age × SNP interaction and cardiometabolic disease associations. 22010049 2012
dbSNP: rs1169288
rs1169288
Entrez Id: 6927;283460
Gene Symbol: HNF1A;HNF1A-AS1
HNF1A;HNF1A-AS1
CUI: C1278049
Disease:
Serum gamma-glutamyl transferase measurement 		G 0.800 GeneticVariation GWASDB Loci affecting gamma-glutamyl transferase in adults and adolescents show age × SNP interaction and cardiometabolic disease associations. 22010049 2012
dbSNP: rs2244608
rs2244608
Entrez Id: 6927;283460
Gene Symbol: HNF1A;HNF1A-AS1
HNF1A;HNF1A-AS1
CUI: C1445957
Disease:
Serum total cholesterol measurement 		0.800 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs2650000
rs2650000
Entrez Id: 283460
Gene Symbol: HNF1A-AS1
HNF1A-AS1
CUI: C0201657
Disease:
C-reactive protein measurement 		0.800 GeneticVariation GWASDB Genome-wide association with C-reactive protein levels in CLHNS: evidence for the CRP and HNF1A loci and their interaction with exposure to a pathogenic environment. 21647738 2012
dbSNP: rs7305618
rs7305618
Entrez Id: 283460
Gene Symbol: HNF1A-AS1
HNF1A-AS1
CUI: C0201657
Disease:
C-reactive protein measurement 		T 0.800 GeneticVariation GWASCAT Genome-wide association with C-reactive protein levels in CLHNS: evidence for the CRP and HNF1A loci and their interaction with exposure to a pathogenic environment. 21647738 2012
dbSNP: rs7305618
rs7305618
Entrez Id: 283460
Gene Symbol: HNF1A-AS1
HNF1A-AS1
CUI: C0201657
Disease:
C-reactive protein measurement 		T 0.800 GeneticVariation GWASDB Genome-wide association with C-reactive protein levels in CLHNS: evidence for the CRP and HNF1A loci and their interaction with exposure to a pathogenic environment. 21647738 2012
dbSNP: rs7953249
rs7953249
Entrez Id: 283460
Gene Symbol: HNF1A-AS1
HNF1A-AS1
CUI: C0201657
Disease:
C-reactive protein measurement 		0.800 GeneticVariation GWASDB Genome-wide association with C-reactive protein levels in CLHNS: evidence for the CRP and HNF1A loci and their interaction with exposure to a pathogenic environment. 21647738 2012
dbSNP: rs7953249
rs7953249
Entrez Id: 283460
Gene Symbol: HNF1A-AS1
HNF1A-AS1
CUI: C0201657
Disease:
C-reactive protein measurement 		G 0.800 GeneticVariation GWASCAT Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease. 23144326 2012
dbSNP: rs1169288
rs1169288
Entrez Id: 6927;283460
Gene Symbol: HNF1A;HNF1A-AS1
HNF1A;HNF1A-AS1
CUI: C1445957
Disease:
Serum total cholesterol measurement 		C 0.800 GeneticVariation GWASDB Biological, clinical and population relevance of 95 loci for blood lipids. 20686565 2010
dbSNP: rs1169288
rs1169288
Entrez Id: 6927;283460
Gene Symbol: HNF1A;HNF1A-AS1
HNF1A;HNF1A-AS1
CUI: C1445957
Disease:
Serum total cholesterol measurement 		C 0.800 GeneticVariation GWASCAT Biological, clinical and population relevance of 95 loci for blood lipids. 20686565 2010
dbSNP: rs1169288
rs1169288
Entrez Id: 6927;283460
Gene Symbol: HNF1A;HNF1A-AS1
HNF1A;HNF1A-AS1
CUI: C0202117
Disease:
Low density lipoprotein cholesterol measurement 		C 0.800 GeneticVariation GWASDB Biological, clinical and population relevance of 95 loci for blood lipids. 20686565 2010
dbSNP: rs1169288
rs1169288
Entrez Id: 6927;283460
Gene Symbol: HNF1A;HNF1A-AS1
HNF1A;HNF1A-AS1
CUI: C0202117
Disease:
Low density lipoprotein cholesterol measurement 		C 0.800 GeneticVariation GWASCAT Biological, clinical and population relevance of 95 loci for blood lipids. 20686565 2010
dbSNP: rs2650000
rs2650000
Entrez Id: 283460
Gene Symbol: HNF1A-AS1
HNF1A-AS1
CUI: C0202117
Disease:
Low density lipoprotein cholesterol measurement 		A 0.800 GeneticVariation GWASDB Common variants at 30 loci contribute to polygenic dyslipidemia. 19060906 2009
dbSNP: rs2650000
rs2650000
Entrez Id: 283460
Gene Symbol: HNF1A-AS1
HNF1A-AS1
CUI: C0202117
Disease:
Low density lipoprotein cholesterol measurement 		A 0.800 GeneticVariation GWASCAT Common variants at 30 loci contribute to polygenic dyslipidemia. 19060906 2009
dbSNP: rs1169288
rs1169288
Entrez Id: 6927;283460
Gene Symbol: HNF1A;HNF1A-AS1
HNF1A;HNF1A-AS1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.780 GeneticVariation BEFREE The Common <i>HNF1A</i> Variant I27L Is a Modifier of Age at Diabetes Diagnosis in Individuals With HNF1A-MODY. 29895593 2018
dbSNP: rs1169288
rs1169288
Entrez Id: 6927;283460
Gene Symbol: HNF1A;HNF1A-AS1
HNF1A;HNF1A-AS1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		C 0.780 GeneticVariation GWASCAT Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes. 29632382 2018
dbSNP: rs1169288
rs1169288
Entrez Id: 6927;283460
Gene Symbol: HNF1A;HNF1A-AS1
HNF1A;HNF1A-AS1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.780 GeneticVariation BEFREE Mutation p.T130I was associated with both early-onset and late-onset diabetes and caused downregulated HNF4A expression, whereas HNF1A polymorphisms p.I27L and p.S487N were associated with the age of diagnosis of diabetes. 26981542 2016
dbSNP: rs1169288
rs1169288
Entrez Id: 6927;283460
Gene Symbol: HNF1A;HNF1A-AS1
HNF1A;HNF1A-AS1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.780 GeneticVariation BEFREE These findings suggest that the HNF1A p.I27L (rs1169288) variant may be a significant risk factor of T2DM in normal-weight subjects and that earlier inconsistent results may have been due, in part, to subjects' weight status. 24933231 2015