DisGeNET - a database of gene-disease associations

APC, APC regulator of WNT signaling pathway, 324

N. diseases: 703; N. variants: 681

Disease: Colorectal Neoplasms ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs121913332

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Comprehensive molecular characterization of human colon and rectal cancer.

22810696

2012

dbSNP:

rs74535574

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Comprehensive molecular characterization of human colon and rectal cancer.

22810696

2012

dbSNP:

rs74535574

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Comprehensive mutation analysis in colorectal flat adenomas.

22848674

2012

dbSNP:

rs121913331

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Molecular genetic analysis of 103 sporadic colorectal tumours in Czech patients.

21901162

2011

dbSNP:

rs121913332

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Molecular genetic analysis of 103 sporadic colorectal tumours in Czech patients.

21901162

2011

dbSNP:

rs121913329

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Prevalence of mutations in APC, CTNNB1, and BRAF in Tunisian patients with sporadic colorectal cancer.

18992635

2008

dbSNP:

rs121913329

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Genetic alterations of APC, K-ras, p53, MSI, and MAGE in Korean colorectal cancer patients.

17704924

2008

dbSNP:

rs121913332

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Prevalence of mutations in APC, CTNNB1, and BRAF in Tunisian patients with sporadic colorectal cancer.

18992635

2008

dbSNP:

rs121913332

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Mutations of the APC gene in human sporadic colorectal cancers.

12374230

2002

dbSNP:

rs74535574

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Mutations of the APC gene in human sporadic colorectal cancers.

12374230

2002

dbSNP:

rs121913327

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

"APC mutations in sporadic colorectal tumors: A mutational ""hotspot"" and interdependence of the ""two hits""."

10737795

2000

dbSNP:

rs121913328

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

"APC mutations in sporadic colorectal tumors: A mutational ""hotspot"" and interdependence of the ""two hits""."

10737795

2000

dbSNP:

rs121913332

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

"APC mutations in sporadic colorectal tumors: A mutational ""hotspot"" and interdependence of the ""two hits""."

10737795

2000

dbSNP:

rs74535574

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

"APC mutations in sporadic colorectal tumors: A mutational ""hotspot"" and interdependence of the ""two hits""."

10737795

2000

dbSNP:

rs121913326

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Characteristics of somatic mutation of the adenomatous polyposis coli gene in colorectal tumors.

8187091

1994

dbSNP:

rs121913327

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Characteristics of somatic mutation of the adenomatous polyposis coli gene in colorectal tumors.

8187091

1994

dbSNP:

rs121913329

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Characteristics of somatic mutation of the adenomatous polyposis coli gene in colorectal tumors.

8187091

1994

dbSNP:

rs121913331

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Characteristics of somatic mutation of the adenomatous polyposis coli gene in colorectal tumors.

8187091

1994

dbSNP:

rs121913332

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Characteristics of somatic mutation of the adenomatous polyposis coli gene in colorectal tumors.

8187091

1994

dbSNP:

rs121913333

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Characteristics of somatic mutation of the adenomatous polyposis coli gene in colorectal tumors.

8187091

1994

dbSNP:

rs121913462

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Characteristics of somatic mutation of the adenomatous polyposis coli gene in colorectal tumors.

8187091

1994

dbSNP:

rs74535574

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Characteristics of somatic mutation of the adenomatous polyposis coli gene in colorectal tumors.

8187091

1994

dbSNP:

rs121913326

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

APC mutations occur early during colorectal tumorigenesis.

1528264

1992

dbSNP:

rs121913327

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene.

1338904

1992

dbSNP:

rs121913327

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

APC mutations occur early during colorectal tumorigenesis.

1528264

1992