DisGeNET - a database of gene-disease associations

APC, APC regulator of WNT signaling pathway, 324

N. diseases: 703; N. variants: 681

Disease: Colorectal Neoplasms ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs755229494

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

GWASCAT

Discovery of common and rare genetic risk variants for colorectal cancer.

30510241

2019

dbSNP:

rs121913326

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Genetic analysis in APC, KRAS, and TP53 in patients with stomach and colon cancer.

24861525

2015

dbSNP:

rs121913327

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Genetic analysis in APC, KRAS, and TP53 in patients with stomach and colon cancer.

24861525

2015

dbSNP:

rs121913328

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Genetic analysis in APC, KRAS, and TP53 in patients with stomach and colon cancer.

24861525

2015

dbSNP:

rs121913332

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Genetic analysis in APC, KRAS, and TP53 in patients with stomach and colon cancer.

24861525

2015

dbSNP:

rs121913462

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Genetic analysis in APC, KRAS, and TP53 in patients with stomach and colon cancer.

24861525

2015

dbSNP:

rs121913326

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Prospective enterprise-level molecular genotyping of a cohort of cancer patients.

25157968

2014

dbSNP:

rs121913327

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Prospective enterprise-level molecular genotyping of a cohort of cancer patients.

25157968

2014

dbSNP:

rs121913328

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Prospective enterprise-level molecular genotyping of a cohort of cancer patients.

25157968

2014

dbSNP:

rs121913328

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

A unique profile of adenomatous polyposis coli gene mutations in Iranian patients suffering sporadic colorectal cancer.

24518971

2014

dbSNP:

rs121913329

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Prospective enterprise-level molecular genotyping of a cohort of cancer patients.

25157968

2014

dbSNP:

rs121913331

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Prospective enterprise-level molecular genotyping of a cohort of cancer patients.

25157968

2014

dbSNP:

rs121913332

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Prospective enterprise-level molecular genotyping of a cohort of cancer patients.

25157968

2014

dbSNP:

rs121913333

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Prospective enterprise-level molecular genotyping of a cohort of cancer patients.

25157968

2014

dbSNP:

rs121913333

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

HD chromoendoscopy coupled with DNA mass spectrometry profiling identifies somatic mutations in microdissected human proximal aberrant crypt foci.

24651453

2014

dbSNP:

rs121913462

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Prospective enterprise-level molecular genotyping of a cohort of cancer patients.

25157968

2014

dbSNP:

rs74535574

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Prospective enterprise-level molecular genotyping of a cohort of cancer patients.

25157968

2014

dbSNP:

rs121913329

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Targeted sequencing of cancer-related genes in colorectal cancer using next-generation sequencing.

23700467

2013

dbSNP:

rs121913331

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Targeted sequencing of cancer-related genes in colorectal cancer using next-generation sequencing.

23700467

2013

dbSNP:

rs121913332

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Targeted sequencing of cancer-related genes in colorectal cancer using next-generation sequencing.

23700467

2013

dbSNP:

rs121913326

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Comprehensive molecular characterization of human colon and rectal cancer.

22810696

2012

dbSNP:

rs121913327

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Comprehensive molecular characterization of human colon and rectal cancer.

22810696

2012

dbSNP:

rs121913327

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

A single-nucleotide substitution mutator phenotype revealed by exome sequencing of human colon adenomas.

23204322

2012

dbSNP:

rs121913328

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

Comprehensive molecular characterization of human colon and rectal cancer.

22810696

2012

dbSNP:

rs121913332

Entrez Id:	324
Gene Symbol:	APC

APC

CUI:	C0009404
Disease:

Colorectal Neoplasms

0.700

GeneticVariation

CLINVAR

A single-nucleotide substitution mutator phenotype revealed by exome sequencing of human colon adenomas.

23204322

2012