|
Blood urea nitrogen measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
A catalog of genetic loci associated with kidney function from analyses of a million individuals.
|
31152163 |
2019 |
|
Alcoholic Intoxication, Chronic
|
|
0.900 |
GeneticVariation
|
BEFREE |
A coding variant in alcohol dehydrogenase 1B (ADH1B) (rs1229984) that leads to the replacement of Arg48 with His48 is common in Asian populations and reduces their risk for alcoholism, but because of very low allele frequencies the effects in European or African populations have been difficult to detect.
|
21968928 |
2012 |
|
Squamous cell carcinoma of esophagus
|
|
0.080 |
GeneticVariation
|
BEFREE |
A dataset composed of 4,220 cases and 8,946 controls from twelve studies of Asian populations was analyzed for ADH1B Arg47His association with ESCC and its interactions with alcohol drinking and ALDH2 Glu504Lys.
|
21048924 |
2010 |
|
Colorectal Carcinoma
|
|
0.050 |
GeneticVariation
|
BEFREE |
A gene-gene interaction between ALDH2 Glu487Lys and ADH2 His47Arg polymorphisms regarding the risk of colorectal cancer in Japan.
|
16332725 |
2006 |
|
Malignant neoplasm of colon and/or rectum
|
|
0.020 |
GeneticVariation
|
BEFREE |
A gene-gene interaction between ALDH2 Glu487Lys and ADH2 His47Arg polymorphisms regarding the risk of colorectal cancer in Japan.
|
16332725 |
2006 |
|
Nasopharyngeal carcinoma
|
|
0.700 |
GeneticVariation
|
GWASDB |
A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci.
|
20512145 |
2010 |
|
Head and Neck Neoplasms
|
|
0.800 |
GeneticVariation
|
GWASCAT |
A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium.
|
21437268 |
2011 |
|
Head and Neck Neoplasms
|
|
0.800 |
GeneticVariation
|
GWASDB |
A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium.
|
21437268 |
2011 |
|
Stomach Carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
A known functional SNP in ADH1B (rs1229984) was associated with alcohol intake (P-value = 0.04) but not GC risk.
|
22144473 |
2012 |
|
Malignant neoplasm of stomach
|
|
0.020 |
GeneticVariation
|
BEFREE |
A known functional SNP in ADH1B (rs1229984) was associated with alcohol intake (P-value = 0.04) but not GC risk.
|
22144473 |
2012 |
|
Alcohol consumption
|
|
0.800 |
GeneticVariation
|
GWASCAT |
A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.
|
23743675 |
2013 |
|
Alcohol consumption
|
|
0.800 |
GeneticVariation
|
GWASDB |
A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.
|
23743675 |
2013 |
|
Alcohol Use Disorder
|
|
0.060 |
GeneticVariation
|
BEFREE |
A significant rs1229984 by childhood adversity interaction was observed for AUD symptoms in EA men.
|
25410943 |
2014 |
|
Drug Dependence
|
|
0.010 |
GeneticVariation
|
BEFREE |
A variant of the ADH1B gene (rs1229984 or Arg48His; previously referred to as Arg [*1] and His [*1]) has been reported to be associated with reduced rates of alcohol and drug dependence.
|
21497796 |
2011 |
|
Esophageal Neoplasms
|
|
0.840 |
GeneticVariation
|
BEFREE |
ADH1B Arg47His polymorphism is associated with esophageal cancer risk in high-incidence Asian population: evidence from a meta-analysis.
|
21048924 |
2010 |
|
Malignant neoplasm of esophagus
|
|
0.750 |
GeneticVariation
|
BEFREE |
ADH1B Arg47His polymorphism is associated with esophageal cancer risk in high-incidence Asian population: evidence from a meta-analysis.
|
21048924 |
2010 |
|
Esophageal carcinoma
|
|
0.040 |
GeneticVariation
|
BEFREE |
ADH1B Arg47His polymorphism is associated with esophageal cancer risk in high-incidence Asian population: evidence from a meta-analysis.
|
21048924 |
2010 |
|
Malignant neoplasm of esophagus
|
|
0.750 |
GeneticVariation
|
BEFREE |
ADH1B rs1229984 polymorphism HRs for HNC and oesophageal cancer death and for alcohol related cancer death were 0.67 (95% CI: 0.42-1.08), and 0.64 (95% CI: 0.40-1.03), respectively.
|
25770642 |
2015 |
|
Malignant Neoplasms
|
|
0.050 |
GeneticVariation
|
BEFREE |
ADH1B rs1229984 polymorphism HRs for HNC and oesophageal cancer death and for alcohol related cancer death were 0.67 (95% CI: 0.42-1.08), and 0.64 (95% CI: 0.40-1.03), respectively.
|
25770642 |
2015 |
|
Primary malignant neoplasm
|
|
0.050 |
GeneticVariation
|
BEFREE |
ADH1B rs1229984 polymorphism HRs for HNC and oesophageal cancer death and for alcohol related cancer death were 0.67 (95% CI: 0.42-1.08), and 0.64 (95% CI: 0.40-1.03), respectively.
|
25770642 |
2015 |
|
Squamous cell carcinoma of the head and neck
|
|
0.030 |
GeneticVariation
|
BEFREE |
ADH1B histidine allele (rs1229984), CYP2E1 rs3813867 heterozygous genotype, and GSTT1 deletion conferred protection against HNSCC (OR: 0.318 [0.04-0.75], OR: 0.13 [0.02-0.94], and OR: 0.12 [0.02-0.60], respectively) while GSTP1 (rs1695) Val/Val genotype was related to an increased risk (OR: 4.12 [1.11-15.31]).
|
25639971 |
2015 |
|
Head and Neck Carcinoma
|
|
0.040 |
GeneticVariation
|
BEFREE |
Alcohol dehydrogenase-1B Arg47His polymorphism is associated with head and neck cancer risk in Asian: a meta-analysis.
|
25323582 |
2015 |
|
Malignant Head and Neck Neoplasm
|
|
0.040 |
GeneticVariation
|
BEFREE |
Alcohol dehydrogenase-1B Arg47His polymorphism is associated with head and neck cancer risk in Asian: a meta-analysis.
|
25323582 |
2015 |
|
Carcinoma of larynx
|
|
0.010 |
GeneticVariation
|
BEFREE |
Alcohol-dehydrogenase (ADH1B) Arg48His polymorphism in Basque Country patients with oral and laryngeal cancer: preliminary study.
|
21378355 |
2011 |
|
Malignant neoplasm of larynx
|
|
0.010 |
GeneticVariation
|
BEFREE |
Alcohol-dehydrogenase (ADH1B) Arg48His polymorphism in Basque Country patients with oral and laryngeal cancer: preliminary study.
|
21378355 |
2011 |