Source: CTD_human

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923 85
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 80
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962 77
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 76
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 76
IL2 P60568 interleukin 2 0.48 0.336 0.885 73
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846 73
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808 67
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846 66
CHRNA7 P36544 Q494W8 cholinergic receptor nicotinic alpha 7 subunit Ion channel 4.2E-04 0.532 0.654 66
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885 66
TYMS P04818 thymidylate synthetase Enzyme 0.72 0.425 0.846 66
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923 65
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923 65
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846 62
NPPA P01160 natriuretic peptide A 5.5E-04 0.505 0.769 61
CYP2E1 P05181 cytochrome P450 family 2 subfamily E member 1 8.1E-09 0.459 0.885 60
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846 60
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923 59
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923 59
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923 58
SERPINA1 P01009 serpin family A member 1 Enzyme modulator 6.8E-08 0.410 0.923 58
EPHX1 P07099 epoxide hydrolase 1 3.2E-09 0.500 0.846 57
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885 57