Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962 109 7
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962 109 1
BCHE P06276 butyrylcholinesterase 1.1E-13 0.447 0.923 108 98
BAP1 Q92560 BRCA1 associated protein 1 Enzyme 0.99 0.454 0.731 108 72
FOS P01100 Fos proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.26 0.411 0.885 104 0
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923 103 4
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962 103 3
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885 100 3
AHR P35869 aryl hydrocarbon receptor Transcription factor 1.00 0.410 0.923 99 10
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923 98 61
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923 98 8
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923 96 6
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 95 5
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808 94 70
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808 93 98
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885 93 2
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923 89 2
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885 89 1
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885 87 79
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885 84 4
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923 83 37
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923 82 6
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 81 1
LEPR P48357 leptin receptor Signaling 0.99 0.433 0.808 79 29