Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
DNM1 Q05193 dynamin 1 Enzyme modulator 1.00 0.595 0.692 2
GSR P00390 glutathione-disulfide reductase Enzyme 1.3E-06 0.494 0.846 31
GAPDH P04406 glyceraldehyde-3-phosphate dehydrogenase Enzyme 0.11 0.447 0.808 10
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846 26
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808 6
HSPD1 P10809 heat shock protein family D (Hsp60) member 1 0.99 0.432 0.808 20
HSF1 Q00613 heat shock transcription factor 1 Transcription factor 0.75 0.507 0.769 12
IKBKB O14920 inhibitor of nuclear factor kappa B kinase subunit beta Kinase 0.99 0.506 0.846 11
INS-IGF2 F8WCM5 INS-IGF2 readthrough 5.6E-02 0.633 0.500 2
INS P01308 insulin 0.30 0.445 0.923 18
IDE P14735 insulin degrading enzyme Enzyme 6.6E-03 0.604 0.577 6
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885 33
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885 28
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846 21
IRS1 P35568 insulin receptor substrate 1 2.4E-02 0.488 0.769 13
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 92
IL33 O95760 interleukin 33 8.3E-10 0.409 0.885 1
IL6 P05231 interleukin 6 0.32 0.248 0.962 54
LRP1 Q07954 LDL receptor related protein 1 1.00 0.482 0.769 12
LEP P41159 leptin 0.46 0.349 0.846 34
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808 12
MT2A P02795 metallothionein 2A 1.2E-05 0.553 0.808 9
MAP2 P11137 microtubule associated protein 2 1.00 0.537 0.692 9
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923 16