| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
major histocompatibility complex, class I, B | 0.379 | 0.885 | 3.9E-05 |
|
disease | 0.500 | None | 0.955 | 179 | 4 | 1980 | 2020 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.100 | None | 0.910 | 145 | 3 | 1991 | 2020 | ||||||||
|
endoplasmic reticulum aminopeptidase 1 | 0.556 | 0.692 | 2.1E-26 |
|
disease | 0.500 | None | 0.979 | 95 | 24 | 2007 | 2020 | ||||||||
|
C-reactive protein | 0.299 | 0.962 | 3.7E-03 |
|
disease | 0.100 | None | 0.944 | 71 | 2 | 1991 | 2020 | ||||||||
|
interleukin 17A | 0.324 | 0.923 | 4.3E-02 |
|
disease | 0.100 | None | 1.000 | 63 | 1 | 2009 | 2020 | ||||||||
|
interleukin 23 receptor | 0.466 | 0.769 | 5.6E-04 |
|
disease | 0.500 | None | 0.964 | 55 | 19 | 2007 | 2019 | ||||||||
|
interleukin 23 subunit alpha | 0.415 | 0.846 | 0.36 |
|
disease | 0.100 | None | 0.968 | 31 | 0 | 2009 | 2020 | ||||||||
|
interleukin 1 alpha | 0.333 | 0.962 | 1.6E-04 |
|
disease | 0.100 | None | 0.920 | 25 | 6 | 2001 | 2020 | ||||||||
|
major histocompatibility complex, class I, C | 0.415 | 0.846 | 1.6E-06 |
|
disease | 0.100 | None | 0.952 | 21 | 0 | 2000 | 2019 | ||||||||
|
interleukin 1 beta | 0.276 | 0.962 | 0.13 |
|
disease | 0.100 | None | 0.900 | 20 | 3 | 2001 | 2020 | ||||||||
|
killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1 | 0.475 | 0.769 | 8.4E-14 |
|
disease | 0.100 | None | 0.895 | 19 | 0 | 2006 | 2019 | ||||||||
|
endoplasmic reticulum aminopeptidase 2 | 0.615 | 0.577 | 1.0E-28 |
|
disease | 0.200 | None | 0.882 | 17 | 5 | 2010 | 2019 | ||||||||
|
melanocortin 2 receptor accessory protein | 0.674 | 0.500 | 2.1E-03 |
|
disease | 0.100 | None | 0.875 | 16 | 0 | 1978 | 2016 | ||||||||
|
interleukin 10 | 0.281 | 0.923 | 5.9E-03 |
|
disease | 0.200 | None | 0.933 | 15 | 3 | 2001 | 2020 | ||||||||
|
major histocompatibility complex, class II, DR beta 1 | 0.333 | 0.923 | 1.1E-03 |
|
disease | 0.100 | None | 0.929 | 14 | 0 | 1997 | 2019 | ||||||||
|
toll like receptor 4 | 0.321 | 0.962 | 4.6E-09 |
|
disease | 0.200 | None | 0.786 | 14 | 2 | 2005 | 2019 | ||||||||
|
interleukin 37 | 0.459 | 0.846 | 1.2E-04 |
|
disease | 0.100 | None | 1.000 | 14 | 1 | 2009 | 2019 | ||||||||
|
dickkopf WNT signaling pathway inhibitor 1 | 0.439 | 0.885 | 0.17 |
|
disease | 0.100 | None | 1.000 | 14 | 1 | 2014 | 2020 | ||||||||
|
TNF receptor superfamily member 1A | 0.409 | 0.923 | 0.99 |
|
disease | 0.200 | None | 1.000 | 14 | 6 | 2005 | 2019 | ||||||||
|
GTP binding protein overexpressed in skeletal muscle | 0.467 | 0.769 | 1.2E-08 |
|
disease | 0.100 | None | 0.923 | 13 | 0 | 2008 | 2019 | ||||||||
|
ANTXR cell adhesion molecule 2 | 0.568 | 0.808 | 8.7E-02 |
|
disease | 0.500 | None | 0.833 | 12 | 7 | 2010 | 2018 | ||||||||
|
MEFV innate immuity regulator, pyrin | 0.440 | 0.885 | 1.0E-14 |
|
disease | 0.200 | None | 1.000 | 12 | 5 | 2008 | 2019 | ||||||||
|
sclerostin | 0.474 | 0.808 | 0.87 |
|
disease | 0.100 | None | 0.909 | 11 | 0 | 2017 | 2020 | ||||||||
|
matrix metallopeptidase 3 | 0.408 | 0.885 | 5.7E-15 |
|
disease | 0.100 | None | 1.000 | 11 | 2 | 2004 | 2019 | ||||||||
|
interleukin 12B | 0.480 | 0.885 | 1.1E-04 |
|
disease | 0.400 | None | 1.000 | 10 | 1 | 2007 | 2019 |