Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7276
Gene Symbol: TTR
TTR
P02766 transthyretin transfer/carrier protein; transporter 258 0.471 0.897 0.55 0.500 0.961 465 6 1981 2018
Entrez Id: 351
Gene Symbol: APP
APP
P05067 amyloid beta precursor protein enzyme modulator 371 0.430 0.862 6.2E-02 0.400 0.971 914 22 1988 2018
Entrez Id: 348
Gene Symbol: APOE
APOE
P02649 apolipoprotein E 770 0.352 0.931 1.7E-03 0.400 0.955 358 2 1993 2018
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1
P49768 presenilin 1 calcium-binding protein; hydrolase; protease; signaling molecule 268 0.490 0.690 0.98 0.400 0.923 170 13 1996 2018
Entrez Id: 43
Gene Symbol: ACHE
ACHE
P22303 acetylcholinesterase (Cartwright blood group) hydrolase; protease 219 0.494 0.793 1.00 0.400 1.000 16 0 1996 2016
Entrez Id: 54503
Gene Symbol: ZDHHC13
ZDHHC13
Q8IUH4 zinc finger DHHC-type containing 13 13 0.743 0.276 3.7E-19 0.300 1 0 2010 2010
Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A
P19438 TNF receptor superfamily member 1A 307 0.443 0.862 1.00 0.150 1.000 5 0 2003 2010
Entrez Id: 23621
Gene Symbol: BACE1
BACE1
P56817 beta-secretase 1 hydrolase; protease 56 0.616 0.517 0.88 0.100 0.990 99 0 1999 2018
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
P10636 microtubule associated protein tau 265 0.492 0.724 7.3E-03 0.100 0.969 97 3 1989 2018
Entrez Id: 3918
Gene Symbol: LAMC2
LAMC2
Q13753 laminin subunit gamma 2 enzyme modulator; extracellular matrix protein; receptor 400 0.419 0.931 3.6E-12 0.100 0.969 65 0 1997 2018
Entrez Id: 5621
Gene Symbol: PRNP
PRNP
F7VJQ1 P04156 prion protein 310 0.474 0.897 7.2E-04 0.100 0.937 63 5 1986 2018
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
P04141 colony stimulating factor 2 signaling molecule 670 0.356 0.966 0.84 0.100 0.967 61 0 1997 2018
Entrez Id: 3375
Gene Symbol: IAPP
IAPP
P10997 islet amyloid polypeptide signaling molecule 87 0.559 0.655 3.1E-03 0.100 0.930 44 1 1990 2018
Entrez Id: 335
Gene Symbol: APOA1
APOA1
P02647 apolipoprotein A1 255 0.463 0.759 5.5E-04 0.100 0.971 36 0 1998 2016
Entrez Id: 2934
Gene Symbol: GSN
GSN
P06396 gelsolin cytoskeletal protein 168 0.498 0.828 3.4E-11 0.100 1.000 35 4 1991 2017
Entrez Id: 4311
Gene Symbol: MME
MME
P08473 membrane metalloendopeptidase hydrolase; protease 237 0.461 0.690 7.0E-17 0.100 1.000 32 0 2002 2016
Entrez Id: 1471
Gene Symbol: CST3
CST3
P01034 cystatin C 167 0.500 0.724 3.9E-03 0.100 1.000 31 0 1983 2014
Entrez Id: 3416
Gene Symbol: IDE
IDE
P14735 insulin degrading enzyme hydrolase; protease 47 0.627 0.483 9.1E-03 0.100 0.967 30 0 2001 2016
Entrez Id: 5664
Gene Symbol: PSEN2
PSEN2
P49810 presenilin 2 hydrolase; protease; signaling molecule 108 0.567 0.517 2.4E-03 0.100 1.000 23 1 1996 2017
Entrez Id: 627
Gene Symbol: BDNF
BDNF
P23560 brain derived neurotrophic factor signaling molecule 591 0.382 0.828 0.70 0.100 0.909 22 2 2003 2018
Entrez Id: 6288
Gene Symbol: SAA1
SAA1
P0DJI8 serum amyloid A1 defense/immunity protein; transfer/carrier protein; transporter 82 0.602 0.655 1.4E-02 0.100 1.000 21 0 1985 2016
Entrez Id: 4210
Gene Symbol: MEFV
MEFV
O15553 MEFV, pyrin innate immunity regulator 199 0.494 0.724 1.0E-14 0.100 0.889 21 4 1999 2015
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
P00441 superoxide dismutase 1 oxidoreductase 456 0.406 0.931 0.13 0.100 1.000 19 1 1992 2016
Entrez Id: 6653
Gene Symbol: SORL1
SORL1
Q92673 sortilin related receptor 1 receptor; transporter 69 0.619 0.483 1.1E-09 0.100 0.947 19 0 2008 2017
Entrez Id: 8803
Gene Symbol: SUCLA2
SUCLA2
Q9P2R7 succinate-CoA ligase ADP-forming beta subunit ligase 104 0.607 0.517 2.6E-03 0.100 1.000 19 0 1998 2016