Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog hydrolase; phosphatase 915 0.334 0.828 0.82 0.800 0.923 16 3 1998 2016
Entrez Id: 3621
Gene Symbol: ING1
ING1
Q9UK53 inhibitor of growth family member 1 nucleic acid binding; transcription factor 59 0.609 0.586 5.2E-02 0.710 1.000 2 3 2000 2000
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.500 0.955 178 77 1991 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor 892 0.325 0.862 0.50 0.500 0.965 148 9 1992 2018
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 891 0.321 0.828 0.38 0.500 0.974 79 9 1994 2018
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha kinase; transferase 835 0.341 0.897 1.00 0.500 0.973 38 29 2001 2017
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 calcium-binding protein; kinase; transfer/carrier protein; transferase 760 0.355 0.862 0.98 0.500 1.000 16 1 2005 2016
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Q16236 nuclear factor, erythroid 2 like 2 cytoskeletal protein; hydrolase; nucleic acid binding; transcription factor 376 0.420 0.862 3.5E-03 0.420 1.000 3 5 2013 2016
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 nucleic acid binding; transcription factor 706 0.358 0.862 1.00 0.400 0.970 34 0 2000 2017
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 oxidoreductase 832 0.338 0.897 1.00 0.400 0.960 26 0 1999 2016
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
P16455 O-6-methylguanine-DNA methyltransferase 293 0.438 0.759 1.1E-07 0.380 0.875 9 0 2004 2015
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase 407 0.405 0.793 0.99 0.370 1.000 7 0 2000 2017
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
P46531 notch 1 389 0.415 0.759 1.00 0.360 1.000 6 0 2011 2016
Entrez Id: 841
Gene Symbol: CASP8
CASP8
Q14790 caspase 8 enzyme modulator; hydrolase; protease 283 0.443 0.793 2.8E-06 0.350 1.000 6 0 2009 2014
Entrez Id: 8900
Gene Symbol: CCNA1
CCNA1
P78396 cyclin A1 enzyme modulator 59 0.598 0.621 4.0E-04 0.330 1.000 4 0 2004 2013
Entrez Id: 7465
Gene Symbol: WEE1
WEE1
P30291 WEE1 G2 checkpoint kinase kinase; transferase 47 0.621 0.483 1.00 0.330 1.000 3 0 2015 2016
Entrez Id: 3236
Gene Symbol: HOXD10
HOXD10
P28358 homeobox D10 47 0.639 0.414 5.6E-02 0.320 1.000 3 0 2012 2015
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
P04179 superoxide dismutase 2 oxidoreductase 488 0.396 0.897 0.16 0.320 1.000 3 0 2007 2012
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
P01583 interleukin 1 alpha 596 0.366 0.931 1.5E-04 0.320 1.000 3 0 2015 2016
Entrez Id: 8795
Gene Symbol: TNFRSF10B
TNFRSF10B
O14763 TNF receptor superfamily member 10b 110 0.540 0.621 1.8E-04 0.320 1.000 2 0 1998 2010
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2
Q9UNQ0 ATP binding cassette subfamily G member 2 (Junior blood group) transporter 265 0.449 0.793 1.3E-32 0.320 1.000 2 0 2014 2015
Entrez Id: 10413
Gene Symbol: YAP1
YAP1
P46937 Yes associated protein 1 149 0.514 0.655 1.00 0.310 1.000 2 0 2011 2015
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
P08183 ATP binding cassette subfamily B member 1 hydrolase; protease 606 0.371 0.828 1.3E-05 0.310 1.000 2 0 2012 2015
Entrez Id: 4363
Gene Symbol: ABCC1
ABCC1
P33527 ATP binding cassette subfamily C member 1 transporter 211 0.479 0.759 6.4E-03 0.310 1.000 2 0 2004 2015
Entrez Id: 1244
Gene Symbol: ABCC2
ABCC2
Q92887 ATP binding cassette subfamily C member 2 transporter 185 0.495 0.690 7.5E-47 0.310 1.000 2 0 2014 2015