Disease: Hypercholesterolemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BUD13 Q9BRD0 BUD13 homolog 2.1E-06 0.751 0.538
UGT1A1 P22309 UDP glucuronosyltransferase family 1 member A1 3.3E-06 0.464 0.769
APOA4 P06727 apolipoprotein A4 5.5E-06 0.582 0.577
NPC1 O15118 NPC intracellular cholesterol transporter 1 Transporter 6.5E-06 0.518 0.692
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846
APOA1 P02647 apolipoprotein A1 5.5E-04 0.429 0.885
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
ASAH2 Q9NR71 N-acylsphingosine amidohydrolase 2 4.3E-03 0.716 0.538
AGTR2 P50052 angiotensin II receptor type 2 G-protein coupled receptor 8.2E-03 0.496 0.808
APOC3 P02656 apolipoprotein C3 1.0E-02 0.531 0.731
FGF21 Q9NSA1 fibroblast growth factor 21 Signaling 2.9E-02 0.485 0.769
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
SCARB1 Q8WTV0 scavenger receptor class B member 1 Receptor 6.6E-02 0.559 0.731
LCAT P04180 lecithin-cholesterol acyltransferase Enzyme 8.1E-02 0.588 0.654
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
ABCG1 P45844 ATP binding cassette subfamily G member 1 Transporter 0.11 0.560 0.692
PLA2G15 Q8NCC3 phospholipase A2 group XV Enzyme 0.38 0.520 0.769
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
VCAM1 P19320 vascular cell adhesion molecule 1 0.80 0.422 0.808
CD40 P25942 CD40 molecule 0.85 0.396 0.846
NR1H3 Q13133 nuclear receptor subfamily 1 group H member 3 Nuclear receptor 0.90 0.566 0.692
C3 P01024 complement C3 Enzyme modulator 0.90 0.445 0.885