Disease: Hypercholesterolemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846
IKBKB O14920 inhibitor of nuclear factor kappa B kinase subunit beta Kinase 0.99 0.506 0.846
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
FGF21 Q9NSA1 fibroblast growth factor 21 Signaling 2.9E-02 0.485 0.769
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
ENG P17813 endoglin 1.00 0.446 0.846
EDNRA P25101 endothelin receptor type A G-protein coupled receptor 0.99 0.426 0.885
DHCR7 Q9UBM7 7-dehydrocholesterol reductase Enzyme 3.9E-13 0.500 0.846
CYP2B6 P20813 cytochrome P450 family 2 subfamily B member 6 1.9E-10 0.428 0.846
CYP27A1 Q02318 cytochrome P450 family 27 subfamily A member 1 Enzyme 5.3E-19 0.538 0.731
CETP P11597 cholesteryl ester transfer protein 1.2E-23 0.512 0.731
CD40 P25942 CD40 molecule 0.85 0.396 0.846
CD36 P16671 CD36 molecule Receptor 1.1E-60 0.446 0.846
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CAD P27708 carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase Enzyme 1.00 0.482 0.846
C3 P01024 complement C3 Enzyme modulator 0.90 0.445 0.885
BUD13 Q9BRD0 BUD13 homolog 2.1E-06 0.751 0.538
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
ASAH2 Q9NR71 N-acylsphingosine amidohydrolase 2 4.3E-03 0.716 0.538
ARNTL O00327 aryl hydrocarbon receptor nuclear translocator like Transcription factor 0.99 0.510 0.885
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APOC3 P02656 apolipoprotein C3 1.0E-02 0.531 0.731