Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3782886
rs3782886
0.700 GeneticVariation GWASDB "ALDH2 is associated to alcohol dependence and is the major genetic determinant of ""daily maximum drinks"" in a GWAS study of an isolated rural Chinese sample." 24277619

2014

dbSNP: rs6318
rs6318
0.030 GeneticVariation BEFREE 5-HT2C Cys23Ser allele frequencies and genotypes did not differ among patients with alcohol dependence, panic disorder, generalized anxiety disorder, narcolepsy and normal healthy volunteers. 10994642

2000

dbSNP: rs11558538
rs11558538
0.030 GeneticVariation BEFREE Thr105Ile, a functional polymorphism of histamine N-methyltransferase, is associated with alcoholism in two independent populations. 15770103

2005

dbSNP: rs6313
rs6313
0.040 GeneticVariation BEFREE T102C polymorphism of the serotonin receptor 2A gene (5-HT2A) has been shown to be associated with certain diseases such as non-fatal acute myocardial infarction, essential hypertension, and alcoholism. 17713649

2007

dbSNP: rs1611115
rs1611115
DBH
0.010 GeneticVariation BEFREE rs1611115 (near 5') C-allele and related haplotypes were significantly associated with alcohol dependence in females. 23906995

2013

dbSNP: rs1997794
rs1997794
0.020 GeneticVariation BEFREE A candidate haplotype containing the PDYN rs2281285-rs1997794 SNPs that was previously associated with alcohol dependence was also associated with negative craving (p = 0.024) and alcohol dependence (p = 0.0008) in this study. 23101464

2013

dbSNP: rs1229984
rs1229984
0.900 GeneticVariation BEFREE A coding variant in alcohol dehydrogenase 1B (ADH1B) (rs1229984) that leads to the replacement of Arg48 with His48 is common in Asian populations and reduces their risk for alcoholism, but because of very low allele frequencies the effects in European or African populations have been difficult to detect. 21968928

2012

dbSNP: rs6296
rs6296
0.080 GeneticVariation BEFREE A fixed-effect model was chosen, and the pooled result showed that rs6296 was not related to al</span>coholism (z = 1.93, <i>p</i> = .053). 31510870

2019

dbSNP: rs4680
rs4680
0.070 GeneticVariation BEFREE A functional COMT polymorphism, Val158Met (rs4680 G > A), affects the onset of AD and is associated with alcohol dependence through dopamine receptor sensitivity in the prefrontal cortex. 25491588

2015

dbSNP: rs16139
rs16139
0.040 GeneticVariation BEFREE A functional neuropeptide Y Leu7Pro polymorphism associated with alcohol dependence in a large population sample from the United States. 12215082

2002

dbSNP: rs10913569
rs10913569
0.700 GeneticVariation GWASDB A genome-wide association study of alcohol dependence. 20202923

2010

dbSNP: rs896543
rs896543
0.800 GeneticVariation GWASDB A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53. 23089632

2013

dbSNP: rs12006002
rs12006002
0.700 GeneticVariation GWASDB A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53. 23089632

2013

dbSNP: rs12898460
rs12898460
0.700 GeneticVariation GWASDB A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53. 23089632

2013

dbSNP: rs12901215
rs12901215
0.700 GeneticVariation GWASDB A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53. 23089632

2013

dbSNP: rs12903120
rs12903120
0.700 GeneticVariation GWASDB A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53. 23089632

2013

dbSNP: rs12912251
rs12912251
0.700 GeneticVariation GWASDB A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53. 23089632

2013

dbSNP: rs12916379
rs12916379
0.700 GeneticVariation GWASDB A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53. 23089632

2013

dbSNP: rs1451724
rs1451724
0.700 GeneticVariation GWASDB A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53. 23089632

2013

dbSNP: rs17616845
rs17616845
0.700 GeneticVariation GWASDB A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53. 23089632

2013

dbSNP: rs1995364
rs1995364
0.700 GeneticVariation GWASDB A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53. 23089632

2013

dbSNP: rs2132157
rs2132157
0.700 GeneticVariation GWASDB A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53. 23089632

2013

dbSNP: rs2172835
rs2172835
0.700 GeneticVariation GWASDB A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53. 23089632

2013

dbSNP: rs34141940
rs34141940
0.700 GeneticVariation GWASDB A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53. 23089632

2013

dbSNP: rs34281605
rs34281605
0.700 GeneticVariation GWASDB A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53. 23089632

2013