Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs509749
rs509749
LY9
0.010 GeneticVariation BEFREE A characteristic single-nucleotide polymorphism (SNP) in each of 9 genetic factors, ITGAM (rs1143679), C8orf13-BLK (rs13277113), TYK2 (rs2304256), 1q25.1 (rs10798269), PXK (rs6445975), KIAA1542 (rs4963128), MECP2 (rs17435), BANK1 (rs17266594), and LY9 (rs509749), was studied in 1,635 patients with RA and 1,906 control subjects from Spain. 19714582

2009
dbSNP: rs1980422
rs1980422 		0.820 GeneticVariation BEFREE A Combination of CD28 (rs1980422) and IRF5 (rs10488631) Polymorphisms Is Associated with Seropositivity in Rheumatoid Arthritis: A Case Control Study. 27092776

2016
dbSNP: rs10488631
rs10488631
TNPO3
0.820 GeneticVariation BEFREE A Combination of CD28 (rs1980422) and IRF5 (rs10488631) Polymorphisms Is Associated with Seropositivity in Rheumatoid Arthritis: A Case Control Study. 27092776

2016
dbSNP: rs2546133
rs2546133
VAV1
0.010 GeneticVariation BEFREE A combination of the previous MS-associated haplotype and two additional SNPs was associated with anti-CCP negative RA (alleles G-G-A-A of rs682626-rs2546133-rs2617822-rs12979659, OR=1.13, P=1.27 × 10<sup>-5</sup>). 28053322

2017
dbSNP: rs2617822
rs2617822
VAV1
0.010 GeneticVariation BEFREE A combination of the previous MS-associated haplotype and two additional SNPs was associated with anti-CCP negative RA (alleles G-G-A-A of rs682626-rs2546133-rs2617822-rs12979659, OR=1.13, P=1.27 × 10<sup>-5</sup>). 28053322

2017
dbSNP: rs2004640
rs2004640
IRF5
0.790 GeneticVariation BEFREE A combined analysis including all 3 independent cohorts from the previous study revealed an association of the rs2004640 with RA (pooled OR 1.21, 95% CI 1.07-1.38, pooled p = 0.0031 in dominant model). 18843785

2008
dbSNP: rs2476601
rs2476601
PTPN22 ; AP4B1-AS1
1.000 GeneticVariation GWASCAT A combined large-scale meta-analysis identifies COG6 as a novel shared risk locus for rheumatoid arthritis and systemic lupus erythematosus. 27193031

2017
dbSNP: rs2736340
rs2736340 		0.830 GeneticVariation GWASCAT A combined large-scale meta-analysis identifies COG6 as a novel shared risk locus for rheumatoid arthritis and systemic lupus erythematosus. 27193031

2017
dbSNP: rs9603612
rs9603612
COG6
0.710 GeneticVariation GWASCAT A combined large-scale meta-analysis identifies COG6 as a novel shared risk locus for rheumatoid arthritis and systemic lupus erythematosus. 27193031

2017
dbSNP: rs12531711
rs12531711
TNPO3
0.700 GeneticVariation GWASCAT A combined large-scale meta-analysis identifies COG6 as a novel shared risk locus for rheumatoid arthritis and systemic lupus erythematosus. 27193031

2017
dbSNP: rs2283790
rs2283790
UBE2L3
0.700 GeneticVariation GWASCAT A combined large-scale meta-analysis identifies COG6 as a novel shared risk locus for rheumatoid arthritis and systemic lupus erythematosus. 27193031

2017
dbSNP: rs4921283
rs4921283 		0.700 GeneticVariation GWASCAT A combined large-scale meta-analysis identifies COG6 as a novel shared risk locus for rheumatoid arthritis and systemic lupus erythematosus. 27193031

2017
dbSNP: rs5029924
rs5029924
TNFAIP3 ; WAKMAR2
0.700 GeneticVariation GWASCAT A combined large-scale meta-analysis identifies COG6 as a novel shared risk locus for rheumatoid arthritis and systemic lupus erythematosus. 27193031

2017
dbSNP: rs6568431
rs6568431
ATG5
0.700 GeneticVariation GWASCAT A combined large-scale meta-analysis identifies COG6 as a novel shared risk locus for rheumatoid arthritis and systemic lupus erythematosus. 27193031

2017
dbSNP: rs7258015
rs7258015
ICAM3
0.700 GeneticVariation GWASCAT A combined large-scale meta-analysis identifies COG6 as a novel shared risk locus for rheumatoid arthritis and systemic lupus erythematosus. 27193031

2017
dbSNP: rs147846074
rs147846074
AIRE
0.010 GeneticVariation BEFREE A genetic variant in the SAND domain of autoimmune regulator (AIRE), R247C, was identified in a patient with type I diabetes mellitus (T1DM) and his mother with rheumatoid arthritis. 29129473

2018
dbSNP: rs1943199
rs1943199 		0.700 GeneticVariation GWASCAT A genome-wide association study of rheumatoid arthritis without antibodies against citrullinated peptides. 24532677

2015
dbSNP: rs2596565
rs2596565 		0.700 GeneticVariation GWASCAT A genome-wide association study of rheumatoid arthritis without antibodies against citrullinated peptides. 24532677

2015
dbSNP: rs3790022
rs3790022
GUCY1B2 ; RNASEH2B
0.700 GeneticVariation GWASCAT A genome-wide association study of rheumatoid arthritis without antibodies against citrullinated peptides. 24532677

2015
dbSNP: rs9271348
rs9271348 		0.700 GeneticVariation GWASCAT A genome-wide association study of rheumatoid arthritis without antibodies against citrullinated peptides. 24532677

2015
dbSNP: rs9557321
rs9557321
CLYBL ; LOC101927437
0.700 GeneticVariation GWASCAT A genome-wide association study of rheumatoid arthritis without antibodies against citrullinated peptides. 24532677

2015
dbSNP: rs9275406
rs9275406 		T 0.800 GeneticVariation GWASDB A genome-wide association study reveals ARL15, a novel non-HLA susceptibility gene for rheumatoid arthritis in North Indians. 23918589

2013
dbSNP: rs9275406
rs9275406 		T 0.800 GeneticVariation GWASCAT A genome-wide association study reveals ARL15, a novel non-HLA susceptibility gene for rheumatoid arthritis in North Indians. 23918589

2013
dbSNP: rs2476601
rs2476601
PTPN22 ; AP4B1-AS1
1.000 GeneticVariation GWASDB A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis. 21156761

2011
dbSNP: rs2476601
rs2476601
PTPN22 ; AP4B1-AS1
1.000 GeneticVariation GWASCAT A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis. 21156761

2011