Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4762
rs4762
AGT
0.100 GeneticVariation BEFREE Angiotensinogen T174M and M235T variants and hypertension in the Hani and Yi minority groups of China. 19365726

2009

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE Angiotensinogen T174M and M235T variants and hypertension in the Hani and Yi minority groups of China. 19365726

2009

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE Although AGT M235T was not associated with the development of hypertension in either sex, men with M235T TT were found to be at an increased risk of IgAN progression compared to those with the other genotypes (p = 0.019). 19729965

2009

dbSNP: rs4762
rs4762
AGT
0.100 GeneticVariation BEFREE Statistically significant associations with hypertension were identified for the T174M (odds ratio [OR]: 1.19; 95% CI: 1.07 to 1.33; P=0.002) and G-217A (OR: 1.37; 95% CI: 1.17 to 1.59; P=0.00006) polymorphisms. 18227406

2008

dbSNP: rs4762
rs4762
AGT
0.100 GeneticVariation BEFREE We studied the effects of the angiotensinogen T174M and M235T, angiotensin converting enzyme insertion/deletion (ACE I/D), and angiotensin II receptor 1 (AT1R) A1166C gene polymorphisms on the risk of hypertension among Hispanics. 18497458

2008

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE We also screened angiotensinogen gene AGT M235T and angiotensin-converting enzyme insertion/deletion polymorphism ACE I/D and found an association between TT genotype and hypertension. 18758497

2008

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE The AGT M235T and eNOS G894T polymorphisms are unlikely to play an important role in the pathogenesis of hypertension in Malays. 17977523

2008

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE We studied the effects of the angiotensinogen T174M and M235T, angiotensin converting enzyme insertion/deletion (ACE I/D), and angiotensin II receptor 1 (AT1R) A1166C gene polymorphisms on the risk of hypertension among Hispanics. 18497458

2008

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE The angiotensinogen gene M235T polymorphism is related to an increased risk of hypertension. 18698203

2008

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE The M235T polymorphism is more common in hypertension and preeclampsia in some populations. 18562701

2008

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE The M235T variant of the angiotensinogen gene is related to development of self-reported hypertension during pregnancy: the Prospect-EPIC cohort study. 18957799

2008

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE Furthermore, an M235T variant of the angiotensinogen (AGT) gene has been associated with hypertension, an important risk factor for the development and progression of diabetic nephropathy. 18413162

2008

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE The M235T polymorphism in the AGT gene has been related to an increased risk of hypertension. 18575631

2008

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE In Slovak population, M235T is associated with increased blood pressure and D allele of ACE gene is associated with MI, chronic CHD and DCM, rather than with hypertension. 17579251

2007

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE M235T polymorphism of the angiotensinogen gene and insertion/deletion polymorphism of the angiotensin-1 converting enzyme gene in essential arterial hypertension in Caucasians. 17448297

2007

dbSNP: rs4762
rs4762
AGT
0.100 GeneticVariation BEFREE A case-control association study was conducted to investigate a possible involvement of polymorphisms of three renin-angiotensin system genes: ACE (I/D and T-3892C), AGT (M235T and T174M), and AT1R (A1166C) in the early development of hypertension. 16876684

2006

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE Conflicting results are to be found in the literature on the relationship between the M235T polymorphism of the angiotensinogen (AGT) gene and hypertension. 16755155

2006

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE People who carried both ACE ID (or DD) and AGT M235T MT (or MM) had more risk to have hypertension. 16685579

2006

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE A case-control association study was conducted to investigate a possible involvement of polymorphisms of three renin-angiotensin system genes: ACE (I/D and T-3892C), AGT (M235T and T174M), and AT1R (A1166C) in the early development of hypertension. 16876684

2006

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE Our results in multiethnic youth uncover an ethnicity and gender-specific effect of the AGT M235T polymorphism and a SES or ethnicity-specific effect of the AGTR1 L191L polymorphism on the progression of hypertension risk. 16790149

2006

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE Earlier studies suggested that a single nucleotide polymorphism (SNP) that converts methionine to threonine at amino acid 235 is associated with hypertension in the Caucasian population. 15854165

2006

dbSNP: rs4762
rs4762
AGT
0.100 GeneticVariation BEFREE The occurrence of the frequent ABCC6 gene mutation c.3421C>T (R1141X) and the hypertension-associated genetic variants T174M and M235T in the angiotensinogen (AGT) gene were determined. 16133423

2005

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE The ACE I/D polymorphism does not contribute to the presence and severity of essential hypertension, while the AGT M235T TT genotype confers a significantly decreased risk for the development of hypertension in the population studied here. 15642127

2005

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE The M235T variant of the AGT is significantly associated with essential hypertension whereas the genotype TT or allele T is a possible genetic marker or risk factor for hypertension in Malaysian subjects. 15811183

2005

dbSNP: rs699
rs699
AGT
0.100 GeneticVariation BEFREE The occurrence of the frequent ABCC6 gene mutation c.3421C>T (R1141X) and the hypertension-associated genetic variants T174M and M235T in the angiotensinogen (AGT) gene were determined. 16133423

2005