|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
A systematic search of MEDLINE, EMBASE, the Cochrane Library, and the Chinese databases Wan Fang Med Database, CNKI, and VIP (until November, 2018) was used to identify studies reporting pain (on a visual analogue scale (VAS)), erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and rheumatoid factor (RF) levels, response rate, and the ACR50 rate in patients with RA.
|
31348241 |
2019 |
|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
<b>Results:</b> There were no significant differences between two groups in baseline conventional RA disease activity markers such as RF, erythrocyte sedimentation rate, CRP, and matrix metalloproteinase-3.
|
31422723 |
2019 |
|
Rheumatoid Arthritis
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
HOMA2-IR indexes showed high values for both IR and beta cell production (%B), and low insulin sensitivity (%S) in patients with RA.C reactive protein (beta coef.
|
30299246 |
2019 |
|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
In relation to RA patients, data on medications used and on the following clinical variables were collected: Disease Activity Score-28-ESR; erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) level and rheumatoid factor (RF) level.
|
30892482 |
2019 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Here we show that Leflunomide exerts immunosuppression but limited efficacy in RA individuals distinguished by higher serum C-reactive protein (CRP<sup>Higher</sup>, CRP<sup>H</sup>), whereas the others with satisfactory responsiveness to Leflunomide show lower CRP (CRP<sup>Lower</sup>, CRP<sup>L</sup>).
|
31594926 |
2019 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
In contrast, both antibodies induced early and sustained suppression of RA disease markers, including interleukin (IL)-6, C-reactive protein, IL2RA, and matrix metalloproteinase 1, in DMARD-IR patients.
|
30358109 |
2019 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Gender stratified adjustment of the DAS28-CRP improves inter-score agreement with the DAS28-ESR in rheumatoid arthritis.
|
30590784 |
2019 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
The aim of the current study was to evaluate the cost per response (ACR20/50/70/90 and HAQ-DI) and patient in remission (DAS28-CRP, CDAI, and SDAI) for abatacept relative to adalimumab, in patients with seropositive, erosive early RA in the US, Germany, Spain, and Canada.
|
31240388 |
2019 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Compared to the RA without ILD group, the RA with ILD group had significantly higher titers of rheumatoid factor and the anti-cyclic citrullinated peptide (p = 0.001 for both), higher levels of C-reactive protein (CRP) at the time of RA diagnosis (p = 0.014), and a higher erythrocyte sedimentation rate (p = 0.022) and CRP levels (p < 0.001) throughout the 10-year follow-up period.
|
28352064 |
2019 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
At the end of CR, all VR indexes (p < 005), except QTd, were significantly decreased as did the results for CRP, DAS28, and HAQ (all p < 0.05), and MET and VO2max (p < 0.05 for both) were significantly increased in patients with RA.
|
30177313 |
2019 |
|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Two hundred patients with RA in clinical remission (disease activity score in 28 joints-C-reactive protein [DAS28-CRP] <3.2 and no swollen joints) were enrolled between April 2012 and June 2015.
|
30721294 |
2019 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
RA disease activity and severity were evaluated by the Disease Activity Score 28, the Simplified Disease Activity Index, the Clinical Disease Activity Index, rheumatoid factor, anti-citrullinated protein antibody titers, the erythrocyte sedimentation rate, C-reactive protein, presence of extra-articular manifestations and type of RA therapy.
|
30658685 |
2019 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
The UltraSound Activity score is a valid and reliable measure of inflammation in RA equal to the sum of 28 SJC, a simplified (0/1) US assessment of 11 structures and CRP.
|
31396686 |
2019 |
|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Moreover, ZFAS1 expression was negatively associated with CRP in RA patients (<i>P</i> = 0.002).
|
31736958 |
2019 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
The area under the curve (AUC) to discriminate RA from controls was 0.756 for CRP, 0.714 for ESR and 0.726-0.783 for calprotectin.
|
31665107 |
2019 |
|
Rheumatoid Arthritis
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
<b>Methods:</b> Thirty-one patients with RA (22 women, age 62.4 years, disease duration 13.8 years, prior TCZ duration 35.7 months, 25 intravenous [8 mg/kg/4 weeks] and 6 subcutaneous [162 mg/2 weeks] TCZ treatments, concomitant MTX 8.5 mg/week [35.5%], and prednisolone (PSL) 4.3 mg/day [25.8%]) who showed an inadequate response to TCZ (disease activity score assessing 28 joints with C-reactive protein [DAS28-CRP] 2.9, clinical disease activity index [CDAI] 15.0, 28 secondary inadequate responders) were treated with additional IGU (final dose 41.7 mg/day) and enrolled in this 24-week, multicenter, retrospective study.
|
29882440 |
2019 |
|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Our findings suggest that normal serum MMP-3 levels, in combination with CRP levels or disease activity, are useful for predicting clinical remission and normal physical function in patients with RA.
|
28940139 |
2019 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Negative CRP was an independent factor associated with longer time from RA onset to TJR.
|
31393198 |
2019 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
A total of 177 patients with RA and 150 healthy volunteers participated in this study, which measured lipid hydroperoxides, advanced oxidation protein products (AOPP), nitric oxide metabolites (NOx), carbonyl protein, total radical-trapping antioxidant parameter (TRAP), uric acid (UA), and C-reactive protein (CRP).
|
29644482 |
2018 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Low hemoglobin is a DAS28-CRP-independent predictor of radiographic joint damage progression in MTX-treated patients with early RA.
|
28950430 |
2018 |
|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Circulating adiponectin level was not associated with RA activity based on DAS28 and C-reactive protein (CRP) levels.
|
28205390 |
2018 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Participants in a prospective RA cohort who experienced a decrease or an increase of ≥10 mg/liter in the C-reactive protein (CRP) level at 2 consecutive time points 1 year apart (CRP decrease group and CRP increase group, respectively) were included in this study.
|
29676517 |
2018 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Longitudinal association between CRP and BP was examined using a repeated-measures linear mixed-effects model in RA outpatients with significant change in inflammation at two consecutive time points.
|
29855349 |
2018 |
|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Most patients with RA had low to moderate disease activity [28-joint count Disease Activity Score-C-reactive protein median 3.16, interquartile range (IQR) 2.03-4.05], and 49% were receiving anti-tumor necrosis factor agents.
|
29657146 |
2018 |
|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Circulating IL-10 levels were positively and significantly correlated with RF (r = 0.28), anti-CCP (r = 0.26), CRP (r = 0.17) and mRNA expression levels (r = 0.59) among RA patients.
|
29621504 |
2018 |