|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Patients with autoantibody-positive rheumatoid arthritis (RA) are less likely to experience pregnancy-induced improvement of RA disease activity (DAS28-C reactive protein (CRP)) compared with patients with autoantibody-negative RA.
|
29615411 |
2018 |
|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
There were significant associations of lnc0640 and lnc5150 levels with C-reactive protein in RA patients (P = 0.011 and P = 0.014, respectively), while lnc5150 level was associated with erythrocyte sedimentation rate (P = 0.022).
|
30132973 |
2018 |
|
Rheumatoid Arthritis
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
In rheumatoid arthritis and lupus, genetic variants can restrict CRP elevations during flares.
|
29718222 |
2018 |
|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
We also found that STEAP4 and v-STEAP4 were correlated positively with C-reactive protein and that their expression was decreased after treatment with an interleukin (IL)-6 antagonist in patients with RA.
|
29080328 |
2018 |
|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Serum exosomal miR-548a-3p was negatively associated with levels of CRP, RF, and ESR in serum of patients with RA.
|
29315763 |
2018 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Combination of PTX3 and CRP could serve as better differential diagnostic markers for RA after validation in larger patient cohort.
|
29408170 |
2018 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Nine studies reported a change in C-Reactive Protein (CRP) after atorvastatin treatment, and the pooled analysis showed that atorvastatin decreased CRP in RA patients by x ± SD95% [SMD = -3.033, 95%CI = (-4.460, -1.606), p = .000].
|
29353098 |
2018 |
|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Among patients with RA, low muscle density was associated with higher disease activity, C-reactive protein and interleukin-6 levels, greater total and visceral fat area, lower ALMI Z scores, physical inactivity, and long-term use of glucocorticoids (>1 year).
|
29481721 |
2018 |
|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Validated laboratory parameters for RA diagnosis are higher blood levels of rheumatoid factor IgM (IgM-RF), anti-citrullinated protein autoantibodies (ACPA), C-reactive protein (CRP) levels and erythrocyte sedimentation rate (ESR).
|
30420853 |
2018 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Positive and significant (p<0.05) correlation of circulating IL-1β levels with RF (r=0.232), anti-CCP (r=0.207) and CRP (r=0.166) among RA patients were found.
|
29054755 |
2018 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
ESR and CRP were increased in patients with RA but not in patients with psoriasis.
|
29656791 |
2018 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
In this study, we investigated plasma calprotectin as a disease marker in patients with chronic RA treated with methotrexate (MTX) monotherapy and compared plasma calprotectin with C-reactive protein (CRP) in this matter.
|
29228799 |
2018 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Restriction to RA was maintained after correction for CRP and age.
|
29540200 |
2018 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Periodontal local treatment only affects clinical periodontal status, and it does not alter circulating levels of IL-6, tumor necrosis factor-alpha or C-reactive protein which are associated with RA.
|
29341486 |
2017 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
The objective of the present study was to explore the associations between calprotectin, S100A12, IL-6, VEGF, erythrocyte sedimentation rate, C-reactive protein and a comprehensive US assessment in patients with rheumatoid arthritis (RA) starting biologic disease-modifying anti-rheumatic drug (bDMARD) treatment.
|
28081709 |
2017 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
We have shown that serum levels of reactive oxygen metabolites (ROM) were associated with C-reactive protein (CRP) and disease activity score based on the examination of 28 joints (DAS28) in patients with rheumatoid arthritis (RA); however, their clinical significance as biomarkers has not been elucidated.
|
27858176 |
2017 |
|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Forty consecutive patients who experienced TdP (TdP cohort) were consecutively enrolled and circulating levels of C-reactive protein (CRP) and proinflammatory cytokines (interleukin-6 (IL-6), tumour necrosis factor alpha (TNFα), interleukin-1 (IL-1)) were compared with patients with active rheumatoid arthritis (RA), comorbidity or healthy controls.
|
28490617 |
2017 |
|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
CRP was measured preoperatively as the disease activity marker for rheumatoid arthritis.
|
28853601 |
2017 |
|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
C-reactive protein was also used to measure disease activity in RA patients.
|
28831245 |
2017 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Disease Activity Score in 28 joints (DAS28) is commonly used to evaluate disease activity of rheumatoid arthritis (RA) and is a guide to treatment decision.The aim of this study was to evaluate the impact of lower reporting limit for C-reactive protein (CRP), with respect to intraindividual biological variability, on the calculation of DAS28 and subsequent patient classification.This study consists of 2 sections: a theoretical consideration discussing the performance of CRP in calculating DAS28 taking intraindividual biological variation and lower reporting limit for CRP into account and a cross-sectional study of RA patients applying our theoretical results.
|
28072726 |
2017 |
|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The serum levels of CRP were significantly increased in gouty patients when compared with RA, AS/SpA, and OA patients.
|
28445313 |
2017 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Pre-clinical (1974) ranked biomarker z-score values (1 = lowest, 5 = highest) within matched sets of 1 RA and 4 CN study subjects independently associated with mortality from 1995 through 2015, for both total (CRP, p=0.028 and sIL-2Rα, p=0.030) and CVD (CRP, p=0.005 and sTNF-R1, p=0.003) deaths.
|
27782866 |
2017 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Furthermore, KJD effectively reduced the positive responses for C-reactive protein and rheumatoid arthritis test in FCA-treated rats.
|
28070931 |
2017 |
|
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
MMP-3, DAS28-CRP, SDAI, and HAQ-DI were assessed at baseline and 24 months to evaluate RA state.
|
28936606 |
2017 |
|
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
PsA patients had significantly lower disease activity according to DAS28-ESR (p=0.006) but not according to DAS28-CRP (p=0.319), and lower serum levels of proinflammatory and angiogenic cytokines than RA patients in remission.
|
27749227 |
2017 |