|
Coronary Artery Disease
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
In multivariate analysis, osteoglycin levels were an independent factor for complex lesion but not for CAD.
|
29503411 |
2018 |
|
Constrictive Bronchiolitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Constrictive Bronchiolitis (CB) has been reported in US Operation Iraqi Freedom/Enduring Freedom (OIF/OEF) deployers but not in those from prior US conflicts.
|
30117179 |
2018 |
|
Brain Neoplasms
|
0.010 |
AlteredExpression
|
group |
BEFREE |
OGN mRNA expression was dramatically increased in meningiomas compared to a spectrum of other brain tumors and normal brain.
|
28923059 |
2017 |
|
Meningioma
|
0.010 |
Biomarker
|
disease |
BEFREE |
OGN-overexpressing meningioma cells demonstrated an elevated rate of cell proliferation, cell cycle activation, and colony formation as compared with cells transfected with control vector.
|
28923059 |
2017 |
|
Osteoporosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
OGN may plays a significant role in osteoporosis, which may also provide a potential target for therapeutic intervention of senile osteoporosis characterized by altered differentiation of BMSCs into osteoblasts and adipocytes.
|
29073887 |
2017 |
|
Osteoporosis, Senile
|
0.010 |
Biomarker
|
disease |
BEFREE |
Effects of Osteoglycin (OGN) on treating senile osteoporosis by regulating MSCs.
|
29073887 |
2017 |
|
Alcohol or Other Drugs use
|
0.010 |
Biomarker
|
disease |
BEFREE |
These results demonstrate the promise of a web-based, self-management intervention for difficult-to-engage OEF/OIF veterans with behavioral health and substance use concerns.
|
28270335 |
2017 |
|
Viral myocarditis
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
This study uncovered a previously unidentified 72-kDa variant of OGN that is predominant in cardiac human and mouse samples of viral myocarditis.
|
27878326 |
2017 |
|
Adult Meningioma
|
0.010 |
Biomarker
|
disease |
BEFREE |
OGN-overexpressing meningioma cells demonstrated an elevated rate of cell proliferation, cell cycle activation, and colony formation as compared with cells transfected with control vector.
|
28923059 |
2017 |
|
Chronic Kidney Diseases
|
0.010 |
Biomarker
|
group |
BEFREE |
Our results indicate that serum osteoglycin is a potential predictor of adverse outcomes in patients with CKD.
|
28824047 |
2017 |
|
Meningioma, benign, no ICD-O subtype
|
0.010 |
Biomarker
|
disease |
BEFREE |
OGN-overexpressing meningioma cells demonstrated an elevated rate of cell proliferation, cell cycle activation, and colony formation as compared with cells transfected with control vector.
|
28923059 |
2017 |
|
Limb ischemia
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The expression of OGN was decreased in a limb ischaemia mouse model.
|
28069703 |
2017 |
|
Anorexia
|
0.010 |
Biomarker
|
disease |
BEFREE |
Notably, mimecan-MBP also induced anorexia in A(y)/a and db/db mice.
|
26870797 |
2015 |
|
Heart failure
|
0.010 |
Biomarker
|
disease |
BEFREE |
In human heart failure, osteoglycin is a promising biomarker for ischemic heart failure.
|
25520363 |
2015 |
|
Congestive heart failure
|
0.010 |
Biomarker
|
disease |
BEFREE |
In human heart failure, osteoglycin is a promising biomarker for ischemic heart failure.
|
25520363 |
2015 |
|
Myocardial Infarction
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Adenoviral overexpression of osteoglycin in wild-type mice significantly improved collagen quality, thereby blunting cardiac dilatation and dysfunction after MI.
|
25520363 |
2015 |
|
Cardiac dilatation
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Adenoviral overexpression of osteoglycin in wild-type mice significantly improved collagen quality, thereby blunting cardiac dilatation and dysfunction after MI.
|
25520363 |
2015 |
|
Follicular thyroid carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Four proteins showed significant differences between FA and FTC (peroxisomal proliferator-activated receptor-γ, serum deprivation response protein, osteoglycin, and dipeptidase 1).
|
23751876 |
2013 |
|
Cervical Squamous Cell Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
A differential protein pattern for SCC was, e.g. over-expressed (OE) eukaryotic translation initiation factor 3-2β, neutrophil cytosolic factor 2, annexin A6 (ANXA6), for SVC it was OE cathepsin D, γ-catenin, RAB2A, for both cancers it was OE apolipoprotein E, tropomyosin 3, HSPA8, and underexpressed cytokeratin 13, osteoglycin.
|
21137014 |
2010 |
|
Non-Small Cell Lung Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
This is the first study showing that mimecan could serve as an excellent pathological biomarker to distinguish NSCLCs from SCLCs.
|
19787221 |
2009 |
|
Malignant neoplasm of lung
|
0.010 |
Biomarker
|
disease |
BEFREE |
Therefore, we hypothesize that mimecan could serve as a biomarker for differentiating various histological types of lung cancers.
|
19787221 |
2009 |
|
Hypertensive disease
|
0.010 |
Biomarker
|
group |
BEFREE |
Taken together, these data implicate Ogn as a key regulator of LVM in rats, mice and humans, and suggest that Ogn modifies the hypertrophic response to extrinsic factors such as hypertension and aortic stenosis.
|
18443592 |
2008 |
|
Adenoma
|
0.010 |
AlteredExpression
|
group |
LHGDN |
All adenoma and cancer tissues did not express mimecan, but all normal mucosa did (P < 0.01).
|
17895523 |
2007 |
|
Glaucoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Mimecan and activinA, which have been shown to be upregulated in models of glaucoma, were both found to be elevated in POAG TM.
|
16565384 |
2006 |
|
Glaucoma, Primary Open Angle
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Mimecan and activinA, which have been shown to be upregulated in models of glaucoma, were both found to be elevated in POAG TM.
|
16565384 |
2006 |