|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Leptin/adiponectin imbalance is associated with increased risk of developing obesity and type 2 diabetes mellitus.
|
30841005 |
2019 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.600 |
Biomarker
|
disease |
BEFREE |
In TNFi-treated patients, leptin and resistin significantly increased, whereas no difference was found analyzing adiponectin and adipsin, during the follow-up.Our data may suggest a beneficial effect of IL-1 inhibition on measures of metabolic derangement in RA-associated T2D.
|
30762811 |
2019 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.600 |
Biomarker
|
disease |
BEFREE |
The Effects of Adiponectin and Adiponectin Receptor 1 Levels on Macrovascular Complications Among Patients with Type 2 Diabetes Mellitus.
|
30816670 |
2019 |
|
Kidney Failure, Chronic
|
0.600 |
Biomarker
|
disease |
BEFREE |
The Protective Role of Adiponectin for Lipoproteins in End-Stage Renal Disease Patients: Relationship with Diabetes and Body Mass Index.
|
30911344 |
2019 |
|
Kidney Failure, Chronic
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
In conclusion, higher adiponectin levels are associated with a higher risk of ESRD independent of conventional risk factors, BMI, and metabolic syndrome components.
|
31323071 |
2019 |
|
Obesity
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Obesity is associated to a low-grade inflammation that alters the expression of adiponectin, leptin, IL-6, Monocyte Chemotactic Protein 1 (MCP1), TRAIL, LIGHT/TNFSF14, OPG, and TNFα.
|
31130918 |
2019 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Only FTO rs9939609 A>T polymorphism was associated with obesity and no association was observed with ADIPOQ rs2441666 G>T and ACE rs4340288 DIP.
|
30416093 |
2019 |
|
Obesity
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The aim of this study was to investigate the association between the RANKL and c-Fos gene methylation on obesity with body mass index (BMI), lipid parameters, homeostasis model assessment of insulin resistance (HOMA-IR), plasma leptin, adiponectin and resistin levels.
|
31364017 |
2019 |
|
Obesity
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Psoriasis in obesity: comparison of serum levels of leptin and adiponectin in obese subjects - cases and controls.
|
31090824 |
2019 |
|
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
Pulmonary Hypertension and Obesity: Focus on Adiponectin.
|
30791536 |
2019 |
|
Obesity
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Leptin/adiponectin imbalance is associated with increased risk of developing obesity and type 2 diabetes mellitus.
|
30841005 |
2019 |
|
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
In this study, we investigated the effects of HFD on obesity and insulin resistance in two distinct types of adipose-specific L-PGDS gene knockout (KO) mice: fatty acid binding protein 4 (fabp4, aP2)-Cre/L-PGDS <sup>flox/flox</sup> and adiponectin (AdipoQ)-Cre/L-PGDS <sup>flox/flox</sup> mice.
|
30760783 |
2019 |
|
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
Adiponectin homolog novel osmotin protects obesity/diabetes-induced NAFLD by upregulating AdipoRs/PPARα signaling in ob/ob and db/db transgenic mouse models.
|
30473057 |
2019 |
|
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
We explored the effects of Roux-en-Y gastric bypass (RYGB) on the circulating levels of adiponectin, leptin, and the adiponectin/leptin (Adpn/Lep) ratio in patients with obesity and type 2 diabetes (T2D).
|
31484347 |
2019 |
|
Obesity
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
HDL cholesterol and adiponectin levels were higher in the eutrophic group compared to the obese and excess-weight groups (p<0.01).
|
29856943 |
2019 |
|
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
Adiponectin is an adipokine that improves insulin sensitivity in obesity-related metabolic disorders, including diabetes, but its efficacy is unknown.
|
31048658 |
2019 |
|
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
The therapeutic potential of adiponectin regulation has received interest because of its association with diverse human disease conditions, such as diabetes, obesity, atherosclerosis, and cancer.
|
30672698 |
2019 |
|
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology.
|
31178129 |
2019 |
|
Obesity
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Obesity and diabetes were associated with increased leptin and decreased adiponectin plasma levels, higher protein expression of leptin and IL-6 in SAT, and higher visfatin protein expression in EAT.
|
31533725 |
2019 |
|
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
Adiponectin and PPAR: a setup for intricate crosstalk between obesity and non-alcoholic fatty liver disease.
|
31656991 |
2019 |
|
Obesity
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Low adiponectin levels are commonly observed in human obesity and have been associated with increased pancreatic cancer risk in prospective epidemiologic studies.
|
30745818 |
2019 |
|
Obesity
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Furthermore, adipose tissue from HFSD rats exhibited significantly larger adipocytes, displayed a significant upregulation of leptin and, surprisingly, elevated adiponectin levels, which is in contrast to chronic obesity in humans.
|
29907930 |
2019 |
|
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
Adiponectin plays a role in asthma and obesity, but its effects and mechanism in obesity-related asthma remain elusive.
|
30584969 |
2019 |
|
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
Serum adiponectin concentration was negatively associated with body mass index, waist to hip ratio, low-density lipoprotein cholesterol, total cholesterol, triglycerides, fasting glucose, fasting insulin, homeostatic model assessment of insulin resistance, dyslipidemia and overweight/obesity status (7.76 × 10<sup>-40</sup> ≤ p ≤ 3.00 × 10<sup>-3</sup>).
|
30816311 |
2019 |
|
Obesity
|
0.600 |
Biomarker
|
disease |
BEFREE |
Adiponectin secreted from adipocytes into plasma has anti-aging, anti-obesity and anti-inflammation effects.
|
30474186 |
2019 |