|
rs17689918
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Mixed anxiety and depressive disorder
|
|
0.010 |
GeneticVariation |
BEFREE |
We assess the effects of CRHR1 variant (rs17689918)-by-environment interactions on emotionality and behavioral traits, including anxiety, depression, aggression and antisocial behaviors.
|
29772307 |
2018 |
|
rs242948
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Infantile Spasm
|
|
0.010 |
GeneticVariation |
BEFREE |
Under the assumption of the dominant model, the selected five SNPs, rs4458044, rs171440, rs17689966, rs28364026 and rs242948, showed no association with the risk of infantile spasms and the effectiveness of adrenocorticotropic hormone treatment.
|
25954915 |
2015 |
|
rs242948
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
West Syndrome
|
|
0.010 |
GeneticVariation |
BEFREE |
Under the assumption of the dominant model, the selected five SNPs, rs4458044, rs171440, rs17689966, rs28364026 and rs242948, showed no association with the risk of infantile spasms and the effectiveness of adrenocorticotropic hormone treatment.
|
25954915 |
2015 |
|
rs242941
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Major Depressive Disorder
|
|
0.030 |
GeneticVariation |
BEFREE |
To investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.
|
23157339 |
2013 |
|
rs242941
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Alzheimer's Disease
|
|
0.010 |
GeneticVariation |
BEFREE |
To investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.
|
23157339 |
2013 |
|
rs242941
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Depressive disorder
|
|
0.030 |
GeneticVariation |
BEFREE |
To investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.
|
23157339 |
2013 |
|
rs242941
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Depressed mood
|
|
0.020 |
GeneticVariation |
BEFREE |
To investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.
|
23157339 |
2013 |
|
rs242941
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Mental Depression
|
|
0.020 |
GeneticVariation |
BEFREE |
To investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.
|
23157339 |
2013 |
|
rs1876831
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Depressive Symptoms
|
|
0.010 |
GeneticVariation |
BEFREE |
To determine if single nucleotide polymorphisms of the corticotrophin-releasing hormone binding protein (CRHBP, rs10055255) and CRH receptor type 1 (CRHR1, rs1876831) were associated with posttraumatic stress disorder (PTSD) and depressive symptoms following medical-surgical intensive care unit (ICU) hospitalization.
|
24075295 |
2014 |
|
rs1876831
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Post-Traumatic Stress Disorder
|
|
0.010 |
GeneticVariation |
BEFREE |
To determine if single nucleotide polymorphisms of the corticotrophin-releasing hormone binding protein (CRHBP, rs10055255) and CRH receptor type 1 (CRHR1, rs1876831) were associated with posttraumatic stress disorder (PTSD) and depressive symptoms following medical-surgical intensive care unit (ICU) hospitalization.
|
24075295 |
2014 |
|
rs173365
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Panic Disorder
|
|
0.010 |
GeneticVariation |
BEFREE |
To confirm the association of CRHR1 and CRHR2 with MDD and PD, we investigated 12 single nucleotide polymorphisms (SNPs) (rs4076452, rs7209436, rs110402, rs242924, rs242940, and rs173365 for CRHR1 and rs4722999, rs3779250, rs2267710, rs1076292, rs2284217, and rs226771 for CRHR2) in MDD patients (n = 173), PD patients (n = 180), and healthy controls (n = 285).
|
22467522 |
2012 |
|
rs4792887
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Depressed mood
|
|
0.010 |
GeneticVariation |
BEFREE |
To comprehensively map the genetic variation in CRHR1 in relation to suicidality and depression, as a follow-up to our initial report on SNP rs4792887, we analyzed six new single nucleotide polymorphisms (SNPs), in an extended sample of family trios (n = 672) with suicide attempter offspring, by using family-based association tests.
|
19220485 |
2009 |
|
rs4792887
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Mental Depression
|
|
0.010 |
GeneticVariation |
BEFREE |
To comprehensively map the genetic variation in CRHR1 in relation to suicidality and depression, as a follow-up to our initial report on SNP rs4792887, we analyzed six new single nucleotide polymorphisms (SNPs), in an extended sample of family trios (n = 672) with suicide attempter offspring, by using family-based association tests.
|
19220485 |
2009 |
|
rs4792887
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Depressive disorder
|
|
0.010 |
GeneticVariation |
BEFREE |
To comprehensively map the genetic variation in CRHR1 in relation to suicidality and depression, as a follow-up to our initial report on SNP rs4792887, we analyzed six new single nucleotide polymorphisms (SNPs), in an extended sample of family trios (n = 672) with suicide attempter offspring, by using family-based association tests.
|
19220485 |
2009 |
|
rs12936511
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Mental Depression
|
|
0.010 |
GeneticVariation |
BEFREE |
Thus, while the characteristics of the suicide female attempters remained undetermined, the male suicidal offspring had increased depression intensity related to main genetic effects by exonic SNP rs12936511 and homozygous non-CGC haplotypes.
|
19220485 |
2009 |
|
rs12936511
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Depressed mood
|
|
0.010 |
GeneticVariation |
BEFREE |
Thus, while the characteristics of the suicide female attempters remained undetermined, the male suicidal offspring had increased depression intensity related to main genetic effects by exonic SNP rs12936511 and homozygous non-CGC haplotypes.
|
19220485 |
2009 |
|
rs12936511
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Depressive disorder
|
|
0.010 |
GeneticVariation |
BEFREE |
Thus, while the characteristics of the suicide female attempters remained undetermined, the male suicidal offspring had increased depression intensity related to main genetic effects by exonic SNP rs12936511 and homozygous non-CGC haplotypes.
|
19220485 |
2009 |
|
rs242941
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Asthma attack
|
|
0.010 |
GeneticVariation |
BEFREE |
Thus, CRHR1 gene SNP rs242941 polymorphism is associated with better response to systemic corticosteroid during acute exacerbation of asthma.
|
25712009 |
2015 |
|
rs7209436
|
CRHR1;LINC02210-CRHR1
|
Irritable Bowel Syndrome
|
|
0.030 |
GeneticVariation |
BEFREE |
Three CRH-R1 SNPS (rs110402, rs242924, and rs7209436) were genotyped using salivary DNA from IBS and healthy control subjects (HCs).
|
27497153 |
2016 |
|
rs110402
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Alcoholic Intoxication, Chronic
|
|
0.010 |
GeneticVariation |
BEFREE |
This study examined the influence of an intronic CRHR1 gene variant, rs110402, on brain responses to negative emotional words, negative emotional traits, and alcohol use in adolescents and young adults at high risk for alcoholism.
|
24623788 |
2014 |
|
rs110402
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
child abuse behavior
|
|
0.030 |
GeneticVariation |
BEFREE |
This study examined the contributions of a polymorphism of the corticotropin-releasing hormone receptor type I (CRHR1) gene (rs110402) and a history of child maltreatment--alone and in interaction--to patterns of cortisol reactivity in adolescents.
|
24703172 |
2014 |
|
rs242941
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Perinatal depression in mother
|
|
0.010 |
GeneticVariation |
BEFREE |
There was no statistically significant association of perinatal depression for CRHR1 rs242941 and GR rs41423247 (BclI).
|
26518448 |
2015 |
|
rs242924
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Irritable Bowel Syndrome
|
|
0.020 |
GeneticVariation |
BEFREE |
The TT genotype of rs7209436 (P = 0.01) and rs242924 (P = 0.02) was significantly more common in patients with IBS than in controls.
|
22957021 |
2012 |
|
rs7209436
|
CRHR1;LINC02210-CRHR1
|
Irritable Bowel Syndrome
|
|
0.030 |
GeneticVariation |
BEFREE |
The TT genotype of rs7209436 (P = 0.01) and rs242924 (P = 0.02) was significantly more common in patients with IBS than in controls.
|
22957021 |
2012 |
|
rs173365
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Major Depressive Disorder
|
|
0.010 |
GeneticVariation |
BEFREE |
The T-A-T-G-G haplotype consisting of rs7209436 and rs173365 in CRHR1 was positively associated with MDD.
|
22467522 |
2012 |