Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs12936511
rs12936511
Entrez Id: 1394;100128977;104909134
Gene Symbol: CRHR1;MAPT-AS1;LINC02210-CRHR1
CRHR1;MAPT-AS1;LINC02210-CRHR1
CUI: C0011581
Disease:
Depressive disorder
0.010 GeneticVariation BEFREE Thus, while the characteristics of the suicide female attempters remained undetermined, the male suicidal offspring had increased depression intensity related to main genetic effects by exonic SNP rs12936511 and homozygous non-CGC haplotypes. 19220485 2009
dbSNP: rs12944712
rs12944712
Entrez Id: 1394;104909134
Gene Symbol: CRHR1;LINC02210-CRHR1
CRHR1;LINC02210-CRHR1
CUI: C0038436
Disease:
Post-Traumatic Stress Disorder
0.010 GeneticVariation BEFREE Results indicated that multiple SNPs were associated with acute symptoms at a univariate level, and after correction for multiple testing, rs12944712 was significantly related to acute PTSD symptoms. 21508513 2011
dbSNP: rs12944712
rs12944712
Entrez Id: 1394;104909134
Gene Symbol: CRHR1;LINC02210-CRHR1
CRHR1;LINC02210-CRHR1
CUI: C1269683
Disease:
Major Depressive Disorder
0.010 GeneticVariation BEFREE The sample was subdivided according to sex and smoking status RESULTS: Among nonsmokers, there were nominal associations between MDD and all tested SNPs (rs12944712, P=0.042; rs110402, P=0.031, and rs878886, P=0.040), regardless of sex. 27544317 2016
dbSNP: rs12944712
rs12944712
Entrez Id: 1394;104909134
Gene Symbol: CRHR1;LINC02210-CRHR1
CRHR1;LINC02210-CRHR1
CUI: C0008060
Disease:
child abuse behavior
0.010 GeneticVariation BEFREE FKBP5 (rs1360780) and CRHR1 (rs12944712) polymorphisms significantly interacted with child abuse and adult stress to predict increases in physical health ailments over 3 years. 24099078 2014
dbSNP: rs1396862
rs1396862
Entrez Id: 1394;100128977;104909134
Gene Symbol: CRHR1;MAPT-AS1;LINC02210-CRHR1
CRHR1;MAPT-AS1;LINC02210-CRHR1
CUI: C0030567
Disease:
Parkinson Disease
0.700 GeneticVariation GWASDB Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database. 22438815 2012
dbSNP: rs1396862
rs1396862
Entrez Id: 1394;100128977;104909134
Gene Symbol: CRHR1;MAPT-AS1;LINC02210-CRHR1
CRHR1;MAPT-AS1;LINC02210-CRHR1
CUI: C4528257
Disease:
Corpuscular Hemoglobin Concentration Mean
0.700 GeneticVariation GWASDB Seventy-five genetic loci influencing the human red blood cell. 23222517 2012
dbSNP: rs16940655
rs16940655
Entrez Id: 1394;100128977;104909134
Gene Symbol: CRHR1;MAPT-AS1;LINC02210-CRHR1
CRHR1;MAPT-AS1;LINC02210-CRHR1
CUI: C0525045
Disease:
Mood Disorders
0.010 GeneticVariation BEFREE By single marker analysis we have found an association of rs28536160 of AVPR1b and rs4076452 and rs16940655 of CRHR1 with mood disorders (P=0.036, 0.0013, and 0.003, respectively). 23962971 2013
dbSNP: rs16940665
rs16940665
Entrez Id: 1394;100128977;104909134
Gene Symbol: CRHR1;MAPT-AS1;LINC02210-CRHR1
CRHR1;MAPT-AS1;LINC02210-CRHR1
CUI: C0030567
Disease:
Parkinson Disease
0.700 GeneticVariation GWASDB Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database. 22438815 2012
dbSNP: rs16940665
rs16940665
Entrez Id: 1394;100128977;104909134
Gene Symbol: CRHR1;MAPT-AS1;LINC02210-CRHR1
CRHR1;MAPT-AS1;LINC02210-CRHR1
CUI: C4528257
Disease:
Corpuscular Hemoglobin Concentration Mean
0.700 GeneticVariation GWASDB Seventy-five genetic loci influencing the human red blood cell. 23222517 2012
dbSNP: rs16940665
rs16940665
Entrez Id: 1394;100128977;104909134
Gene Symbol: CRHR1;MAPT-AS1;LINC02210-CRHR1
CRHR1;MAPT-AS1;LINC02210-CRHR1
CUI: C0030567
Disease:
Parkinson Disease
0.700 GeneticVariation GWASDB Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease. 21738487 2011
dbSNP: rs16940668
rs16940668
Entrez Id: 1394;100128977;104909134
Gene Symbol: CRHR1;MAPT-AS1;LINC02210-CRHR1
CRHR1;MAPT-AS1;LINC02210-CRHR1
CUI: C0030567
Disease:
Parkinson Disease
0.700 GeneticVariation GWASDB Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease. 21738487 2011
dbSNP: rs16940674
rs16940674
Entrez Id: 1394;100128977;104909134
Gene Symbol: CRHR1;MAPT-AS1;LINC02210-CRHR1
CRHR1;MAPT-AS1;LINC02210-CRHR1
CUI: C4528257
Disease:
Corpuscular Hemoglobin Concentration Mean
0.700 GeneticVariation GWASDB Seventy-five genetic loci influencing the human red blood cell. 23222517 2012
dbSNP: rs16940674
rs16940674
Entrez Id: 1394;100128977;104909134
Gene Symbol: CRHR1;MAPT-AS1;LINC02210-CRHR1
CRHR1;MAPT-AS1;LINC02210-CRHR1
CUI: C0030567
Disease:
Parkinson Disease
0.700 GeneticVariation GWASDB Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease. 21738487 2011
dbSNP: rs16940676
rs16940676
Entrez Id: 1394;100128977;104909134
Gene Symbol: CRHR1;MAPT-AS1;LINC02210-CRHR1
CRHR1;MAPT-AS1;LINC02210-CRHR1
CUI: C0030567
Disease:
Parkinson Disease
0.700 GeneticVariation GWASDB Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease. 21738487 2011
dbSNP: rs16940677
rs16940677
Entrez Id: 1394;100128977;104909134
Gene Symbol: CRHR1;MAPT-AS1;LINC02210-CRHR1
CRHR1;MAPT-AS1;LINC02210-CRHR1
CUI: C0030567
Disease:
Parkinson Disease
0.700 GeneticVariation GWASDB Genome-wide mapping of IBD segments in an Ashkenazi PD cohort identifies associated haplotypes. 24842889 2014
dbSNP: rs173365
rs173365
Entrez Id: 1394;100128977;104909134
Gene Symbol: CRHR1;MAPT-AS1;LINC02210-CRHR1
CRHR1;MAPT-AS1;LINC02210-CRHR1
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic
0.010 GeneticVariation BEFREE In block 2, rs17689966 (P = 0.018) showed significant and rs173365 (P = 0.026) showed nominally significant, gene × environment (G × E) effects on alcoholism status. 23473364 2013
dbSNP: rs173365
rs173365
Entrez Id: 1394;100128977;104909134
Gene Symbol: CRHR1;MAPT-AS1;LINC02210-CRHR1
CRHR1;MAPT-AS1;LINC02210-CRHR1
CUI: C1269683
Disease:
Major Depressive Disorder
0.010 GeneticVariation BEFREE The T-A-T-G-G haplotype consisting of rs7209436 and rs173365 in CRHR1 was positively associated with MDD. 22467522 2012
dbSNP: rs173365
rs173365
Entrez Id: 1394;100128977;104909134
Gene Symbol: CRHR1;MAPT-AS1;LINC02210-CRHR1
CRHR1;MAPT-AS1;LINC02210-CRHR1
CUI: C0030319
Disease:
Panic Disorder
0.010 GeneticVariation BEFREE To confirm the association of CRHR1 and CRHR2 with MDD and PD, we investigated 12 single nucleotide polymorphisms (SNPs) (rs4076452, rs7209436, rs110402, rs242924, rs242940, and rs173365 for CRHR1 and rs4722999, rs3779250, rs2267710, rs1076292, rs2284217, and rs226771 for CRHR2) in MDD patients (n = 173), PD patients (n = 180), and healthy controls (n = 285). 22467522 2012
dbSNP: rs17425752
rs17425752
Entrez Id: 1394;100128977;104909134
Gene Symbol: CRHR1;MAPT-AS1;LINC02210-CRHR1
CRHR1;MAPT-AS1;LINC02210-CRHR1
CUI: C0030567
Disease:
Parkinson Disease
0.700 GeneticVariation GWASDB Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease. 21738487 2011
dbSNP: rs17689471
rs17689471
Entrez Id: 1394;100128977;104909134
Gene Symbol: CRHR1;MAPT-AS1;LINC02210-CRHR1
CRHR1;MAPT-AS1;LINC02210-CRHR1
CUI: C4528257
Disease:
Corpuscular Hemoglobin Concentration Mean
0.700 GeneticVariation GWASDB Seventy-five genetic loci influencing the human red blood cell. 23222517 2012
dbSNP: rs17689653
rs17689653
Entrez Id: 1394;100128977;104909134
Gene Symbol: CRHR1;MAPT-AS1;LINC02210-CRHR1
CRHR1;MAPT-AS1;LINC02210-CRHR1
CUI: C4528257
Disease:
Corpuscular Hemoglobin Concentration Mean
0.700 GeneticVariation GWASDB Seventy-five genetic loci influencing the human red blood cell. 23222517 2012
dbSNP: rs17689824
rs17689824
Entrez Id: 1394;100128977;104909134
Gene Symbol: CRHR1;MAPT-AS1;LINC02210-CRHR1
CRHR1;MAPT-AS1;LINC02210-CRHR1
CUI: C4528257
Disease:
Corpuscular Hemoglobin Concentration Mean
0.700 GeneticVariation GWASDB Seventy-five genetic loci influencing the human red blood cell. 23222517 2012
dbSNP: rs17689882
rs17689882
Entrez Id: 1394;100128977;104909134
Gene Symbol: CRHR1;MAPT-AS1;LINC02210-CRHR1
CRHR1;MAPT-AS1;LINC02210-CRHR1
CUI: C4528257
Disease:
Corpuscular Hemoglobin Concentration Mean
0.700 GeneticVariation GWASDB Seventy-five genetic loci influencing the human red blood cell. 23222517 2012
dbSNP: rs17689882
rs17689882
Entrez Id: 1394;100128977;104909134
Gene Symbol: CRHR1;MAPT-AS1;LINC02210-CRHR1
CRHR1;MAPT-AS1;LINC02210-CRHR1
CUI: C0086132
Disease:
Depressive Symptoms
0.010 GeneticVariation BEFREE Specifically, we found that the impact of childhood maltreatment on adult depressive symptoms was significantly higher in individuals (i) with two copies of the CRHR1 TAT haplotype, and (ii) homozygous for the G allele of rs17689882. 22748421 2013
dbSNP: rs17689918
rs17689918
Entrez Id: 1394;100128977;104909134
Gene Symbol: CRHR1;MAPT-AS1;LINC02210-CRHR1
CRHR1;MAPT-AS1;LINC02210-CRHR1
CUI: C4528257
Disease:
Corpuscular Hemoglobin Concentration Mean
0.700 GeneticVariation GWASDB Seventy-five genetic loci influencing the human red blood cell. 23222517 2012