|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
Obesity risk is associated with carbohydrate intake in women carrying the Gln27Glu beta2-adrenoceptor polymorphism.
|
12888635 |
2003 |
|
Labor Pain
|
|
0.010 |
GeneticVariation
|
BEFREE |
Labor pain more rapidly became severe in parturients heterozygous or homozygous for the G allele at rs1042714 in the ADRB2 gene.
|
24714117 |
2014 |
|
Diabetes
|
|
0.010 |
GeneticVariation
|
BEFREE |
Gln27Glu variant of the beta2-adrenergic receptor gene is not associated with obesity and diabetes in Japanese-Americans.
|
11288039 |
2001 |
|
Hypertriglyceridemia
|
|
0.020 |
GeneticVariation
|
BEFREE |
Gln27Glu beta2-adrenergic receptor variant is associated with hypertriglyceridemia and the development of fatty liver.
|
11718682 |
2001 |
|
Asthma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Gln/Glu27 polymorphism might be a contributor to asthma susceptibility for adults.
|
24992184 |
2014 |
|
Acute Chest Syndrome
|
|
0.020 |
GeneticVariation
|
BEFREE |
Gln27Glu polymorphism of ADRB2 influences exercise-induced vascular adaptation in patients with ACS.
|
28235084 |
2017 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
A total of 107 unrelated overweight/obese individuals were genotyped for two ADRB2 non-synonymous polymorphisms: Arg16Gly (rs1042713) and Gln27Glu (rs1042714).
|
29331538 |
2018 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
Additionally, for the polymorphic sites of BAR-2 (Arg16Gly and Gln27Glu) a significant effect on obesity risk was seen.
|
12395215 |
2002 |
|
Metabolic Syndrome X
|
|
0.010 |
GeneticVariation
|
BEFREE |
ADRB2 haplotypes (comprising rs1042711, rs1801704, rs1042713 and rs1042714 in that order), genotyping and statistical analysis to evaluate associations with continuous variables and traits related to IR and MS in a PCOS population.
|
22900502 |
2013 |
|
Polycystic Ovary Syndrome
|
|
0.010 |
GeneticVariation
|
BEFREE |
ADRB2 haplotypes (comprising rs1042711, rs1801704, rs1042713 and rs1042714 in that order), genotyping and statistical analysis to evaluate associations with continuous variables and traits related to IR and MS in a PCOS population.
|
22900502 |
2013 |
|
Intraocular pressure disorder
|
|
0.010 |
GeneticVariation
|
BEFREE |
After adjusting for sex, family history of glaucoma, and use of systemic beta-blockers, subjects with the CC genotype at coding single-nucleotide polymorphism rs1042714 in the ADRB2 gene were significantly more likely to experience an IOP decrease of 20% or more (odds ratio, 2.00; 95% confidence interval, 1.00-4.02).
|
18625943 |
2008 |
|
Hypertensive disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
Among 29 candidate single-nucleotide polymorphisms, rs7897633-A in PRKG1, rs434082-A in SLC8A1 and rs1042714-G in ADRB2 were significantly associated with salt-sensitive hypertension.
|
28446801 |
2017 |
|
Hypertensive disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
As Black Americans have an increased risk of hypertension, we evaluated associations between beta(1)-AR (Arg389Gly) and beta(2)-AR (Arg16Gly, Gln27Glu) gene variants and cardiovascular reactivity in 500 Black youth.
|
20374546 |
2010 |
|
Obesity
|
|
0.100 |
GeneticVariation
|
BEFREE |
As there is a high prevalence of obesity in Tonga, we aimed to determine the distribution of the beta2 adrenoceptor gene Gln(27)Glu polymorphism and to assess its relevance to obesity and to Type II diabetes, known to be prevalent in that population.
|
12605574 |
2003 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.040 |
GeneticVariation
|
BEFREE |
As there is a high prevalence of obesity in Tonga, we aimed to determine the distribution of the beta2 adrenoceptor gene Gln(27)Glu polymorphism and to assess its relevance to obesity and to Type II diabetes, known to be prevalent in that population.
|
12605574 |
2003 |
|
Asthma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Asthmatics heterozygous for Gln/Glu27 had significantly later asthma onsets than those homozygous for Gln27.
|
10524541 |
1999 |
|
Coronary Artery Disease
|
|
0.050 |
GeneticVariation
|
BEFREE |
beta1AR (Ser49Gly, Arg389Gly) and beta2AR (Gly16Arg, Gln27Glu) SNPs were genotyped in a case-control study comparing 107 patients with CAD and aborted SCD due to VA with 287 CAD control subjects and 101 healthy control subjects.
|
18534365 |
2008 |
|
Ventricular arrhythmia
|
|
0.010 |
GeneticVariation
|
BEFREE |
beta1AR (Ser49Gly, Arg389Gly) and beta2AR (Gly16Arg, Gln27Glu) SNPs were genotyped in a case-control study comparing 107 patients with CAD and aborted SCD due to VA with 287 CAD control subjects and 101 healthy control subjects.
|
18534365 |
2008 |
|
Cerebrovascular accident
|
|
0.020 |
GeneticVariation
|
BEFREE |
Carriers of the Glu allele of the Gln27Glu polymorphism showed an elevated systolic and diastolic BP, mean arterial pressure, total peripheral resistance index, and a lower stroke volume in EA.
|
12441217 |
2002 |
|
Coronary heart disease
|
|
0.030 |
GeneticVariation
|
BEFREE |
Cigarette smoking, carrier state of A or G allele of 46A>G and 79C>G polymorphisms of beta2-adrenergic receptor gene, and the risk of coronary artery disease.
|
18473266 |
2008 |
|
Coronary Arteriosclerosis
|
|
0.020 |
GeneticVariation
|
BEFREE |
Cigarette smoking, carrier state of A or G allele of 46A>G and 79C>G polymorphisms of beta2-adrenergic receptor gene, and the risk of coronary artery disease.
|
18473266 |
2008 |
|
Hypertensive disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
Common Arg16Gly and Gln27Glu polymorphisms of the beta(2)-adrenergic receptor (beta(2)AR) have been associated with hypertension and coronary disease.
|
15797659 |
2005 |
|
Coronary Artery Disease
|
|
0.050 |
GeneticVariation
|
BEFREE |
Common Arg16Gly and Gln27Glu polymorphisms of the beta(2)-adrenergic receptor (beta(2)AR) have been associated with hypertension and coronary disease.
|
15797659 |
2005 |
|
Coronary heart disease
|
|
0.030 |
GeneticVariation
|
BEFREE |
Common Arg16Gly and Gln27Glu polymorphisms of the beta(2)-adrenergic receptor (beta(2)AR) have been associated with hypertension and coronary disease.
|
15797659 |
2005 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.040 |
GeneticVariation
|
BEFREE |
Common variants in the beta2-(Gln27Glu) and beta3-(Trp64Arg)--adrenoceptor genes are associated with elevated serum NEFA concentrations and type II diabetes.
|
11380082 |
2001 |