| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
amyloid beta precursor protein | 0.422 | 0.846 | 4.7E-02 |
|
disease | 0.700 | strong | 0.964 | 8 | 0 | 1993 | 2020 | ||||||||
|
microtubule associated protein tau | 0.446 | 0.923 | 6.0E-03 |
|
disease | 0.500 | None | 0.992 | 18 | 0 | 1995 | 2020 | ||||||||
|
granulin precursor | 0.435 | 0.846 | 7.0E-02 |
|
disease | 0.500 | None | 1.000 | 16 | 0 | 2006 | 2019 | ||||||||
|
prion protein | 0.445 | 0.923 | 6.3E-04 |
|
disease | 0.500 | strong | 0.958 | 5 | 0 | 1991 | 2019 | ||||||||
|
presenilin 2 | 0.550 | 0.654 | 5.4E-04 |
|
disease | 0.500 | strong | 1.000 | 1 | 0 | 1997 | 2018 | ||||||||
|
apolipoprotein E | 0.338 | 0.962 | 1.9E-03 |
|
disease | 0.200 | None | 0.916 | 25 | 0 | 1994 | 2020 | ||||||||
|
presenilin 1 | 0.469 | 0.846 | 0.97 |
|
disease | 0.200 | None | 0.983 | 10 | 0 | 1990 | 2019 | ||||||||
|
synuclein alpha | 0.427 | 0.885 | 0.88 |
|
disease | 0.200 | None | 0.986 | 8 | 0 | 1998 | 2019 | ||||||||
|
valosin containing protein | 0.469 | 0.923 | 1.00 |
|
disease | 0.200 | None | 0.958 | 4 | 0 | 2005 | 2019 | ||||||||
|
leucine rich repeat kinase 2 | 0.510 | 0.808 | 2.6E-30 |
|
disease | 0.200 | None | 0.812 | 2 | 0 | 2005 | 2019 | ||||||||
|
integral membrane protein 2B | 0.617 | 0.654 | 0.63 |
|
disease | 0.200 | None | 0.966 | 2 | 0 | 1999 | 2019 | ||||||||
|
charged multivesicular body protein 2B | 0.543 | 0.731 | 4.6E-06 |
|
disease | 0.190 | None | 1.000 | 3 | 0 | 2005 | 2016 | ||||||||
|
FMRP translational regulator 1 | 0.473 | 0.769 | 0.65 |
|
disease | 0.160 | None | 1.000 | 2 | 0 | 2007 | 2014 | ||||||||
|
PTEN induced kinase 1 | 0.516 | 0.769 | 1.9E-10 |
|
disease | 0.150 | None | 1.000 | 1 | 0 | 2005 | 2019 | ||||||||
|
serpin family I member 1 | 0.631 | 0.462 | 2.7E-02 |
|
disease | 0.140 | None | 1.000 | 2 | 0 | 2004 | 2018 | ||||||||
|
ataxin 2 | 0.482 | 0.808 | 0.85 |
|
disease | 0.130 | None | 1.000 | 1 | 0 | 1994 | 2017 | ||||||||
|
ATP binding cassette subfamily D member 1 | 0.563 | 0.731 | 1.00 |
|
disease | 0.120 | None | 1.000 | 1 | 0 | 2007 | 2013 | ||||||||
|
junctophilin 3 | 0.608 | 0.538 | 1.00 |
|
disease | 0.120 | None | 1.000 | 1 | 0 | 2007 | 2012 | ||||||||
|
SPG21 abhydrolase domain containing, maspardin | 0.695 | 0.500 | 6.6E-04 |
|
disease | 0.110 | None | 1.000 | 1 | 0 | 2003 | 2003 | ||||||||
|
TAR DNA binding protein | 0.493 | 0.808 | 0.99 |
|
disease | 0.100 | None | 0.935 | 4 | 0 | 2007 | 2020 | ||||||||
|
C-reactive protein | 0.299 | 0.962 | 3.7E-03 |
|
disease | 0.100 | None | 1.000 | 2 | 0 | 2006 | 2020 | ||||||||
|
brain derived neurotrophic factor | 0.345 | 0.923 | 0.66 |
|
disease | 0.100 | None | 1.000 | 1 | 0 | 2007 | 2020 | ||||||||
|
interleukin 1 beta | 0.276 | 0.962 | 0.13 |
|
disease | 0.100 | None | 0.800 | 1 | 0 | 1993 | 2012 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.100 | None | 0.867 | 1 | 0 | 1993 | 2020 | ||||||||
|
insulin like growth factor 1 | 0.318 | 0.885 | 0.27 |
|
disease | 0.080 | None | 0.875 | 1 | 0 | 2002 | 2019 |