Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.210 Biomarker RGD Post-insult ibuprofen treatment attenuates damage to the serotonergic system after hypoxia-ischemia in the immature rat brain. 23147509

2012

Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.210 Biomarker RGD SMND-309, a novel derivative of salvianolic acid B, protects rat brains ischemia and reperfusion injury by targeting the JAK2/STAT3 pathway. 23764464

2013

Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.210 Biomarker RGD Temporal and spatial differences of multiple protein expression in the ischemic penumbra after transient MCAO in rats. 20417628

2010

Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.210 Therapeutic RGD Epigallocatechin Gallate Extends the Therapeutic Window of Recombinant Tissue Plasminogen Activator Treatment in Ischemic Rats. 26851971

2016

Entrez Id: 27113
Gene Symbol: BBC3
BBC3
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.210 Biomarker RGD Gene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway. 12913114

2003

Entrez Id: 286
Gene Symbol: ANK1
ANK1
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.210 Biomarker RGD Distribution of ankyrin isoforms and their proteolysis after ischemia and reperfusion in rat brain. 9202331

1997

Entrez Id: 1020
Gene Symbol: CDK5
CDK5
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.210 Therapeutic RGD Cdk5 is required for the neuroprotective effect of transforming growth factor-β1 against cerebral ischemia-reperfusion. 28254431

2017

Entrez Id: 581
Gene Symbol: BAX
BAX
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.210 Therapeutic RGD Post-treatment of Bax-inhibiting peptide reduces neuronal death and behavioral deficits following global cerebral ischemia. 21167243

2011

Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.210 Biomarker RGD Ibuprofen protects ischemia-induced neuronal injury via up-regulating interleukin-1 receptor antagonist expression. 15837124

2005

Entrez Id: 1991
Gene Symbol: ELANE
ELANE
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Therapeutic RGD Neutrophil elastase inhibitor attenuates hippocampal neuronal damage after transient forebrain ischemia in rats. 19168036

2009

Entrez Id: 8726
Gene Symbol: EED
EED
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Early activation of nSMase2/ceramide pathway in astrocytes is involved in ischemia-associated neuronal damage via inflammation in rat hippocampi. 24007266

2013

Entrez Id: 4152
Gene Symbol: MBD1
MBD1
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Transient forebrain ischemia alters the mRNA expression of methyl DNA-binding factors in the adult rat hippocampus. 12421618

2002

Entrez Id: 84867
Gene Symbol: PTPN5
PTPN5
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Therapeutic RGD Neuroprotective role of a brain-enriched tyrosine phosphatase, STEP, in focal cerebral ischemia. 24198371

2013

Entrez Id: 2332
Gene Symbol: FMR1
FMR1
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Positive feedback regulation of Akt-FMRP pathway protects neurons from cell death. 22817682

2012

Entrez Id: 1627
Gene Symbol: DBN1
DBN1
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Changes in drebrin, MAP2 (postsynaptic marker) and synaptophysin (presynaptic marker) in rat brains were examined after 20 min of transient cerebral ischemia. 8583659

1995

Entrez Id: 5328
Gene Symbol: PLAU
PLAU
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Combination therapy of 17beta-estradiol and recombinant tissue plasminogen activator for experimental ischemic stroke. 19952306

2010

Entrez Id: 27018
Gene Symbol: BEX3
BEX3
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Co-induction of p75NTR and p75NTR-associated death executor in neurons after zinc exposure in cortical culture or transient ischemia in the rat. 11124986

2000

Entrez Id: 84557
Gene Symbol: MAP1LC3A
MAP1LC3A
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Therapeutic RGD Propofol prevents autophagic cell death following oxygen and glucose deprivation in PC12 cells and cerebral ischemia-reperfusion injury in rats. 22509406

2012

Entrez Id: 6194
Gene Symbol: RPS6
RPS6
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Roles of Sestrin2 and Ribosomal Protein S6 in Transient Global Ischemia-Induced Hippocampal Neuronal Injury. 26556340

2015

Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Differential expression of small heat shock proteins in reactive astrocytes after focal ischemia: possible role of beta-adrenergic receptor. 10559386

1999

Entrez Id: 84867
Gene Symbol: PTPN5
PTPN5
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Neuroprotective role of a brain-enriched tyrosine phosphatase, STEP, in focal cerebral ischemia. 24198371

2013

Entrez Id: 7225
Gene Symbol: TRPC6
TRPC6
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Therapeutic RGD Neuroprotective effect of resveratrol on ischemia/reperfusion injury in rats through TRPC6/CREB pathways. 23435869

2013

Entrez Id: 65125
Gene Symbol: WNK1
WNK1
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD WNK-Cab39-NKCC1 signaling increases the susceptibility to ischemic brain damage in hypertensive rats. 27798271

2017

Entrez Id: 857
Gene Symbol: CAV1
CAV1
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Therapeutic RGD Caveolin-1 regulates nitric oxide-mediated matrix metalloproteinases activity and blood-brain barrier permeability in focal cerebral ischemia and reperfusion injury. 22007835

2012

Entrez Id: 3181
Gene Symbol: HNRNPA2B1
HNRNPA2B1
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Histochemical mapping of hnRNP A2/B1 in rat brain after ischemia-reperfusion insults. 20421594

2010