Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8567
Gene Symbol: MADD
MADD
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD The onset of apoptosis of neurons induced by ischemia-reperfusion injury is delayed by transient period of hypertension in rats. 12625816

2003

Entrez Id: 25942
Gene Symbol: SIN3A
SIN3A
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Increased binding of stroke-induced long non-coding RNAs to the transcriptional corepressors Sin3A and coREST. 24063527

2013

Entrez Id: 2745
Gene Symbol: GLRX
GLRX
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Localization of glutaredoxin (thioltransferase) in the rat brain and possible functional implications during focal ischemia. 10329397

1999

Entrez Id: 1843
Gene Symbol: DUSP1
DUSP1
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Over-expression of map kinase phosphatase-1 (MKP-1) suppresses neuronal death through regulating JNK signaling in hypoxia/re-oxygenation. 22197701

2012

Entrez Id: 3551
Gene Symbol: IKBKB
IKBKB
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Therapeutic RGD [Influence of electroacupuncture intervention on hippocampal IL-1beta content and I kappa B kinase beta expression in focal cerebral ischemia/reperfusion rats]. 24261295

2013

Entrez Id: 7073
Gene Symbol: TIAL1
TIAL1
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Expression of the RNA-binding protein TIAR is increased in neurons after ischemic cerebral injury. 10700014

2000

Entrez Id: 10804
Gene Symbol: GJB6
GJB6
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Hydrogen supplemented air inhalation reduces changes of prooxidant enzyme and gap junction protein levels after transient global cerebral ischemia in the rat hippocampus. 21718970

2011

Entrez Id: 4747
Gene Symbol: NEFL
NEFL
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Effects of brain ischemia on intermediate filaments of rat hippocampus. 8726968

1996

Entrez Id: 1386
Gene Symbol: ATF2
ATF2
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Persistent phosphorylation of cyclic AMP responsive element-binding protein and activating transcription factor-2 transcription factors following transient cerebral ischemia in rat brain. 10077326

1999

Entrez Id: 90411
Gene Symbol: MCFD2
MCFD2
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Mutations in the MCFD2 gene are predominant among patients with hereditary combined FV and FVIII deficiency (F5F8D) in India. 17610559

2007

Entrez Id: 5764
Gene Symbol: PTN
PTN
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Upregulation of pleiotrophin gene expression in developing microvasculature, macrophages, and astrocytes after acute ischemic brain injury. 9570800

1998

Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Therapeutic RGD Combined preconditioning with hypoxia and GYKI-52466 protects rats from cerebral ischemic injury by HIF-1α/eNOS pathway. 29312485

2017

Entrez Id: 1385
Gene Symbol: CREB1
CREB1
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Persistent phosphorylation of cyclic AMP responsive element-binding protein and activating transcription factor-2 transcription factors following transient cerebral ischemia in rat brain. 10077326

1999

Entrez Id: 3182
Gene Symbol: HNRNPAB
HNRNPAB
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Therapeutic RGD Microarray analysis of the global gene expression profile following hypothermia and transient focal cerebral ischemia. 22366221

2012

Entrez Id: 841
Gene Symbol: CASP8
CASP8
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Therapeutic RGD Hypoxic preconditioning attenuates necroptotic neuronal death induced by global cerebral ischemia via Drp1-dependent signaling pathway mediated by CaMKIIα inactivation in adult rats. 30148677

2019

Entrez Id: 3274
Gene Symbol: HRH2
HRH2
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Postischemic regulation of central histamine receptors. 16181737

2005

Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Therapeutic RGD Propofol prevents autophagic cell death following oxygen and glucose deprivation in PC12 cells and cerebral ischemia-reperfusion injury in rats. 22509406

2012

Entrez Id: 9927
Gene Symbol: MFN2
MFN2
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Mfn2 downregulation in excitotoxicity causes mitochondrial dysfunction and delayed neuronal death. 25147362

2014

Entrez Id: 3312
Gene Symbol: HSPA8
HSPA8
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Assembly of proteins to postsynaptic densities after transient cerebral ischemia. 9425004

1998

Entrez Id: 6558
Gene Symbol: SLC12A2
SLC12A2
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD WNK-Cab39-NKCC1 signaling increases the susceptibility to ischemic brain damage in hypertensive rats. 27798271

2017

Entrez Id: 4602
Gene Symbol: MYB
MYB
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Regulation of ischemic neuronal death by E2F4-p130 protein complexes. 24828495

2014

Entrez Id: 1235
Gene Symbol: CCR6
CCR6
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD Macrophage inflammatory protein-3alpha plays a key role in the inflammatory cascade in rat focal cerebral ischemia. 19428685

2009

Entrez Id: 4313
Gene Symbol: MMP2
MMP2
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Therapeutic RGD Effects of acupuncture at GV20 and ST36 on the expression of matrix metalloproteinase 2, aquaporin 4, and aquaporin 9 in rats subjected to cerebral ischemia/reperfusion injury. 24828425

2014

Entrez Id: 65266
Gene Symbol: WNK4
WNK4
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD WNK-Cab39-NKCC1 signaling increases the susceptibility to ischemic brain damage in hypertensive rats. 27798271

2017

Entrez Id: 2697
Gene Symbol: GJA1
GJA1
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack
0.200 Biomarker RGD The role of connexin 43 and hemichannels correlated with the astrocytic death following ischemia/reperfusion insult. 23328809

2013