|
rs10859871
|
|
C |
0.850 |
GeneticVariation |
GWASDB |
In addition, we establish an association of rs13394619 in GREB1 at 2p25.1 with endometriosis and identify a newly associated locus at 12q22 near VEZT (rs10859871).
|
23104006 |
2012 |
|
rs10859871
|
|
|
0.850 |
GeneticVariation |
BEFREE |
In addition, we establish an association of rs13394619 in GREB1 at 2p25.1 with endometriosis and identify a newly associated locus at 12q22 near VEZT (rs10859871).
|
23104006 |
2012 |
|
rs10859871
|
|
|
0.850 |
GeneticVariation |
BEFREE |
In the present study, an association of rs7521902 (WNT4) and rs10859871 (VEZT) was confirmed in women with endometriosis at the genotypic but not the allelic level.
|
28901453 |
2017 |
|
rs10859871
|
|
|
0.850 |
GeneticVariation |
BEFREE |
Endometriosis risk SNPs (including rs10859871) located within this locus demonstrated evidence for ITALIC! cis-eQTLs on ITALIC!VEZT expression.
|
27005890 |
2016 |
|
rs10859871
|
|
C |
0.850 |
GeneticVariation |
GWASCAT |
In addition, we establish an association of rs13394619 in GREB1 at 2p25.1 with endometriosis and identify a newly associated locus at 12q22 near VEZT (rs10859871).
|
23104006 |
2012 |
|
rs10859871
|
|
|
0.850 |
GeneticVariation |
BEFREE |
Genome-wide and candidate-gene association studies for endometriosis have identified 10 independent risk loci, and of these, nine (rs7521902, rs13394619, rs4141819, rs6542095, rs1519761, rs7739264, rs12700667, rs1537377, and rs10859871) are polymorphic in European populations.
|
26337243 |
2015 |
|
rs10859871
|
|
|
0.850 |
GeneticVariation |
BEFREE |
Meta-analysis with previous data confirmed the rs10859871 </span>SNP as that with the strongest evidence for association with endometriosis (OR = 1.19, 95% CI: 1.15-1.24, P = 7.9 × 10(-20)).
|
25678572 |
2015 |
|
rs7521902
|
|
|
0.850 |
GeneticVariation |
BEFREE |
Genome-wide and candidate-gene association studies for endometriosis have identified 10 independent risk loci, and of these, nine (rs7521902, rs13394619, rs4141819, rs6542095, rs1519761, rs7739264, rs12700667, rs1537377, and rs10859871) are polymorphic in European populations.
|
26337243 |
2015 |
|
rs7521902
|
|
A |
0.850 |
GeneticVariation |
GWASCAT |
Genome-wide association study link novel loci to endometriosis.
|
23472165 |
2013 |
|
rs7521902
|
|
|
0.850 |
GeneticVariation |
BEFREE |
The meta-analysis showed that rs7521902 was associated with endometriosis at a genome-wide significance (p(meta)=2.23×10(-9)) while for rs1250248, a genome-wide significant p(meta) value of 3.89×10(-9) was detected only in association with severe forms.
|
23142796 |
2013 |
|
rs7521902
|
|
A |
0.850 |
GeneticVariation |
GWASCAT |
Genome-wide association meta-analysis identifies new endometriosis risk loci.
|
23104006 |
2012 |
|
rs7521902
|
|
A |
0.850 |
GeneticVariation |
GWASDB |
Genome-wide association meta-analysis identifies new endometriosis risk loci.
|
23104006 |
2012 |
|
rs7521902
|
|
|
0.850 |
GeneticVariation |
BEFREE |
In the present study, an association of rs7521902 (WNT4) and rs10859871 (VEZT) was confirmed in women with endometriosis at the genotypic but not the allelic level.
|
28901453 |
2017 |
|
rs7521902
|
|
|
0.850 |
GeneticVariation |
BEFREE |
No significant association was found between endometriosis and rs7521902 (A/C), rs16826658 (G/T), or rs7515106 (C/T).
|
25682310 |
2015 |
|
rs7521902
|
|
|
0.850 |
GeneticVariation |
BEFREE |
TaqMan allelic discrimination technique was used to investigate the relationship between endometriosis and four single-nucleotide polymorphisms (rs16826658, rs3820282, rs2235529, and rs7521902) in WNT4 gene.
|
26139156 |
2015 |
|
rs13394619
|
|
|
0.840 |
GeneticVariation |
BEFREE |
Fine mapping results identified a number of SNPs showing stronger association (0.004 < P < 0.032) with endometriosis risk than the original GWAS SNP (rs13394619) (P = 0.034).
|
25788566 |
2015 |
|
rs13394619
|
|
G |
0.840 |
GeneticVariation |
GWASCAT |
In addition, we establish an association of rs13394619 in GREB1 at 2p25.1 with endometriosis and identify a newly associated locus at 12q22 near VEZT (rs10859871).
|
23104006 |
2012 |
|
rs13394619
|
|
|
0.840 |
GeneticVariation |
BEFREE |
Notably, three coding variants in GREB1 (near rs13394619) and CDKN2B-AS1 (near rs1537377) also showed nominally significant associations with endometriosis.
|
26337243 |
2015 |
|
rs13394619
|
|
|
0.840 |
GeneticVariation |
BEFREE |
In addition, we establish an association of rs13394619 in GREB1 at 2p25.1 with endometriosis and identify a newly associated locus at 12q22 near VEZT (rs10859871).
|
23104006 |
2012 |
|
rs13394619
|
|
|
0.840 |
GeneticVariation |
BEFREE |
Is it possible to replicate the genetic association of single nucleotide polymorphisms (SNPs) rs13394619, rs4141819, rs7739264, rs17694933 and rs10859871 in five genetic loci previously identified as associated with endometriosis in an Italian Caucasian population?
|
25678572 |
2015 |
|
rs13394619
|
|
G |
0.840 |
GeneticVariation |
GWASDB |
In addition, we establish an association of rs13394619 in GREB1 at 2p25.1 with endometriosis and identify a newly associated locus at 12q22 near VEZT (rs10859871).
|
23104006 |
2012 |
|
rs10965235
|
|
C |
0.820 |
GeneticVariation |
GWASDB |
Through a genome-wide association study and a replication study using a total of 1,907 Japanese individuals with endometriosis (cases) and 5,292 controls, we identified a significant association of endometriosis with rs10965235 (P = 5.57 x 10(-12), odds ratio = 1.44), which is located in CDKN2BAS on chromosome 9p21, encoding the cyclin-dependent kinase inhibitor 2B antisense RNA.
|
20601957 |
2010 |
|
rs10965235
|
|
C |
0.820 |
GeneticVariation |
GWASCAT |
Through a genome-wide association study and a replication study using a total of 1,907 Japanese individuals with endometriosis (cases) and 5,292 controls, we identified a significant association of endometriosis with rs10965235 (P = 5.57 x 10(-12), odds ratio = 1.44), which is located in CDKN2BAS on chromosome 9p21, encoding the cyclin-dependent kinase inhibitor 2B antisense RNA.
|
20601957 |
2010 |
|
rs10965235
|
|
|
0.820 |
GeneticVariation |
BEFREE |
Our results suggest that the rs10965235 SNP in the CDKN2B-AS gene and the rs16826658 SNP near the WNT4 gene were significantly associated with endometriosis in this Korean population.
|
25154675 |
2014 |
|
rs10965235
|
|
|
0.820 |
GeneticVariation |
BEFREE |
Through a genome-wide association study and a replication study using a total of 1,907 Japanese individuals with endometriosis (cases) and 5,292 controls, we identified a significant association of endometriosis with rs10965235 (P = 5.57 x 10(-12), odds ratio = 1.44), which is located in CDKN2BAS on chromosome 9p21, encoding the cyclin-dependent kinase inhibitor 2B antisense RNA.
|
20601957 |
2010 |