|
rs1202989817
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Endometriosis is not associated with gene mutations for p53codon72, TNF-308 G/A, VEGF-1154G/A, SOD Ala16Val.
|
23167810 |
2013 |
|
rs1457582183
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Endometriosis is not associated with gene mutations for p53codon72, TNF-308 G/A, VEGF-1154G/A, SOD Ala16Val.
|
23167810 |
2013 |
|
rs372201428
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Endometriosis is not associated with gene mutations for p53codon72, TNF-308 G/A, VEGF-1154G/A, SOD Ala16Val.
|
23167810 |
2013 |
|
rs4880
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Endometriosis is not associated with gene mutations for p53codon72, TNF-308 G/A, VEGF-1154G/A, SOD Ala16Val.
|
23167810 |
2013 |
|
rs763000109
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Endometriosis is not associated with gene mutations for p53codon72, TNF-308 G/A, VEGF-1154G/A, SOD Ala16Val.
|
23167810 |
2013 |
|
rs10859871
|
|
|
0.850 |
GeneticVariation |
BEFREE |
Endometriosis risk SNPs (including rs10859871) located within this locus demonstrated evidence for ITALIC! cis-eQTLs on ITALIC!VEZT expression.
|
27005890 |
2016 |
|
rs1042522
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Arg72Pro p53 polymorphism in Italian women: no association with endometriosis.
|
17412337 |
2007 |
|
rs1131691014
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Arg72Pro p53 polymorphism in Italian women: no association with endometriosis.
|
17412337 |
2007 |
|
rs878854066
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Arg72Pro p53 polymorphism in Italian women: no association with endometriosis.
|
17412337 |
2007 |
|
rs2292596
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A cross-sectional comparative study among women who underwent surgical treatment for endometriosis revealed that frequency of the Ala/Ala genotype at aryl hydrocarbon receptor repressor (AHRR) Pro185Ala polymorphism was three times higher (27.6% vs. 9.9%) in the younger group (<or=30 years) than in the older group (>30 years).
|
19501819 |
2009 |
|
rs12030576
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A known dysmenorrhea signal near NGF replicated in our data (rs12030576; P = 1.1 × 10<sup>-19</sup>) and was associated with RP4-663N10.1 expression, a putative lncRNA enhancer of NGF, while a novel dysmenorrhea signal in the IL1 locus (rs80111889; P = 1.9 × 10<sup>-16</sup>) contained SNPs previously associated with endometriosis, and GWAS SNPs were most significantly associated with IL1A expression.
|
29855537 |
2018 |
|
rs80111889
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A known dysmenorrhea signal near NGF replicated in our data (rs12030576; P = 1.1 × 10<sup>-19</sup>) and was associated with RP4-663N10.1 expression, a putative lncRNA enhancer of NGF, while a novel dysmenorrhea signal in the IL1 locus (rs80111889; P = 1.9 × 10<sup>-16</sup>) contained SNPs previously associated with endometriosis, and GWAS SNPs were most significantly associated with IL1A expression.
|
29855537 |
2018 |
|
rs1250248
|
|
|
0.030 |
GeneticVariation |
BEFREE |
A non-significant trend towards the association of rs1250248 with moderate/severe endometriosis was observed (odds ratio 1.18, 95% confidence interval 0.97-1.44).
|
23315067 |
2013 |
|
rs7574865
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A single-polymorphism analysis revealed that the TT genotype of the rs7574865/T > G polymorphism was significantly more frequent in women with minimal or mild endometriosis than in the controls (10% vs. 5%, p = 0.047).
|
30887509 |
2019 |
|
rs16826658
|
|
|
0.750 |
GeneticVariation |
BEFREE |
A SNP, rs16826658, in the LD block including WNT4 on chromosome 1p36, which is considered to play an important role in the development of the female genital tract, revealed a possible association with endometriosis (P = 1.66 x 10(-6), odds ratio = 1.20).
|
20601957 |
2010 |
|
rs3798573
|
|
|
0.010 |
GeneticVariation |
BEFREE |
According to the genotypes and the patients' histories, we found that the ESR1 polymorphism rs3798573 A/G was associated with risk of endometriosis and infertile endometriosis in Han women from central China.
|
23177411 |
2013 |
|
rs3918242
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Additionally, we performed two meta-analyses for MMP9 rs3918242 polymorphism in endometriosis/adenomyosis and preeclampsia but found no association with either disorder.
|
29309889 |
2018 |
|
rs9434741
|
|
|
0.010 |
GeneticVariation |
BEFREE |
After correction for multiple comparisons, rs9434741 (CHD5) remained significantly associated with endometriosis (p<0.01).
|
22910690 |
2012 |
|
rs3756712
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Although no association has been found between ED risk and the allele frequencies of rs3756712 locus (a marginal P=0.066, OR=1.27, 95% CI=0.98-1.65), but in a dominant model, increased endometriosis risk was significantly associated with rs3756712 polymorphism (OR=1.54, 95% CI=1.11-2.17).
|
23137875 |
2013 |
|
rs1056836
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Although no association was found between serum PCB TEQ level and advanced endometriosis in any stratum of CYP1B1 Leu432Val polymorphism, a statistically significant interaction was found (P for interaction = 0.05).
|
17449539 |
2007 |
|
rs17561
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Although the exact mechanism through which this SNP alters risk of ovarian cancer is not clearly understood, rs17561 has also been associated with risk of endometriosis, an epidemiologic risk factor for ovarian cancer.
|
24272484 |
2014 |
|
rs4783689
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Although this study was limited by sample size, the E-cadherin gene polymorphism rs4783689 was marginally associated with endometriosis in the Japanese population, suggesting that E-cadherin might be involved in genetic susceptibility to endometriosis.
|
22434855 |
2012 |
|
rs4986790
|
|
|
0.010 |
GeneticVariation |
BEFREE |
An association of G allele, GG, and AG genotype of TLR4 A896G polymorphism was seen in cases of endometriosis.
|
21214494 |
2011 |
|
rs11651755
|
|
|
0.010 |
GeneticVariation |
BEFREE |
As rs11651755 in HNF1B modified both the ovarian cancer risk and also the risk for endometriosis, HNF1B may be causally involved in the pathogenetic pathway leading from endometriosis to ovarian cancer.
|
28214017 |
2017 |
|
rs3820282
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Association mapping results from 7,090 individuals (2,594 cases and 4,496 controls) supported rs3820282 as the SNP with the strongest association for endometriosis risk (P = 1.84 × 10−5, OR = 1.244 (1.126-1.375)).
|
28171565 |
2016 |