|
rs2070074
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Compared with endometriosis cases without the N314D allele, those cases with the allele tended to have more advanced disease and a family history of endometriosis.
|
9238674 |
1996 |
|
rs2070074
|
|
|
0.050 |
GeneticVariation |
BEFREE |
There were no significant differences observed in the N314D mutation frequency between women with endometriosis (18%) and controls (17%).
|
9714048 |
1998 |
|
rs2070074
|
|
|
0.050 |
GeneticVariation |
BEFREE |
We conclude that the galactose-1-phosphate uridyl transferase N314D polymorphism is unlikely to be associated with endometriosis in the UK population.
|
10508229 |
1999 |
|
rs2070074
|
|
|
0.050 |
GeneticVariation |
BEFREE |
To investigate a possible association between the carrier frequency of the N314D mutation in the galactose-1-phosphate uridyl transferase (GALT) gene and endometriosis and linkage to the short arm of chromosome 9, where the GALT gene resides.
|
11704127 |
2001 |
|
rs5498
|
|
|
0.050 |
GeneticVariation |
BEFREE |
In contrast, the allele and genotype frequencies of the E/K469 polymorphism did not differ significantly between endometriosis and control groups.
|
12529420 |
2003 |
|
rs1799969
|
|
|
0.040 |
GeneticVariation |
BEFREE |
While the functional correlate of the G/R241 polymorphism remains unclear, this finding indicates that a genetic polymorphism in the ICAM-1 gene domain may contribute to the susceptibility to endometriosis.
|
12529420 |
2003 |
|
rs1801282
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Association of peroxisome proliferator-activated receptor gamma 2 Pro-12-Ala polymorphism with endometriosis.
|
15136115 |
2004 |
|
rs1805192
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Association of peroxisome proliferator-activated receptor gamma 2 Pro-12-Ala polymorphism with endometriosis.
|
15136115 |
2004 |
|
rs1232898090
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of peroxisome proliferator-activated receptor gamma 2 Pro-12-Ala polymorphism with endometriosis.
|
15136115 |
2004 |
|
rs1799864
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We have used real-time PCR and FRET technologies to genotype and evaluate the variants CCR5-Delta32 and CCR2-V64I, as susceptibility factors in a cohort of Spanish women with endometriosis.
|
14981141 |
2004 |
|
rs605059
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Evidence for association between the Ser312Gly polymorphism in HSD17B1 and endometriosis was found in a Japanese population.
|
15640252 |
2005 |
|
rs700519
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Here, we evaluated whether the risk and severity of endometriosis are associated with polymorphisms in estradiol-synthesizing enzyme genes: the Ser312Gly polymorphism in 17-beta-hydroxysteroid dehydrogenase type 1 (HSD17B1) and the Arg264Cys polymorphism in cytochrome P450, subfamily XIX (CYP19).
|
15640252 |
2005 |
|
rs500760
|
|
|
0.010 |
GeneticVariation |
BEFREE |
TDT showed weak evidence of allelic association between endometriosis and rs500760 (P = 0.027) but not in the expected direction.
|
16126772 |
2005 |
|
rs2070074
|
|
|
0.050 |
GeneticVariation |
BEFREE |
These findings suggest that Q188R and N314D mutations are not likely to be associated with an increased risk of endometriosis among Chinese Women.
|
16416427 |
2006 |
|
rs5498
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Our results suggest that the IL-6 -634C/G and ICAM-1 469K/E polymorphisms synergistically affect the susceptibility for endometriosis in the Japanese population.
|
16938116 |
2006 |
|
rs75391579
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These findings suggest that Q188R and N314D mutations are not likely to be associated with an increased risk of endometriosis among Chinese Women.
|
16416427 |
2006 |
|
rs9340773
|
|
|
0.010 |
GeneticVariation |
BEFREE |
DNA samples from endometriosis lesions and control tissues from the same collectives were also analyzed for the exonic G229A polymorphism.
|
16388018 |
2006 |
|
rs1042522
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Arg72Pro p53 polymorphism in Italian women: no association with endometriosis.
|
17412337 |
2007 |
|
rs1131691014
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Arg72Pro p53 polymorphism in Italian women: no association with endometriosis.
|
17412337 |
2007 |
|
rs878854066
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Arg72Pro p53 polymorphism in Italian women: no association with endometriosis.
|
17412337 |
2007 |
|
rs25487
|
|
|
0.030 |
GeneticVariation |
BEFREE |
We concluded that XRCC1 Arg399Gln polymorphism is associated with higher susceptibility to endometriosis and XRCC1 Arg399Gln polymorphism might be a useful biomarker for endometriosis.
|
18442016 |
2007 |
|
rs1048943
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Neither CYP1A1 Ile462Val and CYP1B1 Leu432Val polymorphisms (genotypes with versus genotypes without the minor allele) nor serum dioxin and PCB toxic equivalency (TEQ) levels (low versus high) were independently associated with either early or advanced endometriosis risk.
|
17449539 |
2007 |
|
rs1056836
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Although no association was found between serum PCB TEQ level and advanced endometriosis in any stratum of CYP1B1 Leu432Val polymorphism, a statistically significant interaction was found (P for interaction = 0.05).
|
17449539 |
2007 |
|
rs700518
|
|
|
0.010 |
GeneticVariation |
BEFREE |
CYP19 115T>C, 240G>A, and 1531C>T polymorphisms and [TTTA]n tetranucleotide repeat polymorphisms in the CYP19 gene and their haplotypes were not significantly associated with the risk of endometriosis.
|
17687621 |
2007 |
|
rs3025039
|
|
|
0.040 |
GeneticVariation |
BEFREE |
To further investigate the reported association between VEGF variants and endometriosis, we tested the four VEGF polymorphisms (-2578 A/C, rs699947; -460 T/C, rs833061; +405 G/C, rs2010963 and +936 C/T, rs3025039) in a large Australian sample of 958 familial endometriosis cases and 959 controls.
|
18650217 |
2008 |