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rs1042752
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found that rs1042752-located in the 3'-UTR of POU2AF1, which plays a vital role in lymphomagenesis-was significantly associated with lymphoma risk in a case-control study with 793 patients and 939 controls.
|
28345816 |
2017 |
|
rs10494879
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Five hundred patients with aggressive NHL treated with CHOP/CHOEP were analyzed for IL-10 gene polymorphisms, including distal loci -7400InDel, -6752AT (rs6676671), and -6208CG (rs10494879) in comparison with proximal loci -3538AT (rs1800890), -1087AG (rs1800896), and -597AC (rs1800872) according to the incidence and outcome of the lymphoma.
|
18559596 |
2008 |
|
rs1057519781
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Activation of IGF-1R pathway and NPM-ALK G1269A mutation confer resistance to crizotinib treatment in NPM-ALK positive lymphoma.
|
31177400 |
2019 |
|
rs1131691014
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Through searching PubMed databases (or hand searching) up to April 2012 using the following MeSH terms and keywords: "p53", "codon 72" "polymorphism" and "leukemia", or "lymphoma", or "myeloma", thirteen were identified as eligible articles in this meta-analysis for p53 Arg72Pro polymorphism (2,731 cases and 7, 356 controls), including nine studies on leukemia (1,266 cases and 4, 474 controls), three studies on lymphoma (1,359 cases and 2,652 controls), and one study on myeloma.
|
23029260 |
2012 |
|
rs11466782
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The ADAM19 rs11466782 SNP was associated with an increased risk of lymphoma (OR, 1.73; 95% CI, 1.28-2.35; Padditive=0.0004), and the ICAM3 rs2304240 (OR, 0.67; 95% CI, 0.52-0.86; Padditive=0.002) and the PTGDR rs708486 SNPs (OR, 0.75; 95% CI, 0.63-0.90; Padditive=0.002) were associated with reduced risk of lymphoma.
|
21239057 |
2011 |
|
rs11547328
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We propose that similarly to typical human MCL and its blastoid or cyclin-D1 variants that correspond to the same genetic entity, MCL-like lymphomas of c-myc-3'RR/ p53+/- mice and c-myc-3'RR/Cdk4(R24C) mice represent a spectrum of the same entity.
|
22592113 |
2012 |
|
rs121913105
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Constitutive phosphorylation of c-Cbl by the K650M mutant appeared to be related to the intracellular retention of the receptor.
|
17509076 |
2007 |
|
rs121913237
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Using a bone marrow transplant model, we previously showed that ∼ 95% of animals receiving Nras G12D/+ bone marrow cells develop chronic myelomonocytic leukemia (CMML), while ∼ 8% of recipients develop acute T-cell lymphoblastic leukemia/lymphoma [TALL] (TALL-het).
|
21586752 |
2011 |
|
rs121913482
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Internalization of the R248C and Y373C mutant receptors, which form stable disulfide-bonded dimers at the cell surface was less efficient than the wild-type, whereas ubiquitylation was markedly increased but apparently independent of the E3 ubiquitin-ligase casitas B-lineage lymphoma (c-Cbl).
|
17509076 |
2007 |
|
rs121913485
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Internalization of the R248C and Y373C mutant receptors, which form stable disulfide-bonded dimers at the cell surface was less efficient than the wild-type, whereas ubiquitylation was markedly increased but apparently independent of the E3 ubiquitin-ligase casitas B-lineage lymphoma (c-Cbl).
|
17509076 |
2007 |
|
rs121913503
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The test evaluates the expression of 20 genes, including 17 markers relevant to T-cell immunology and lymphoma biopathology, one EBV-related transcript, and variants of RHOA (G17V) and IDH2 (R172K/T).
|
31488561 |
2019 |
|
rs121913529
|
|
|
0.010 |
GeneticVariation |
BEFREE |
MYC-, K-ras(G12D)- or MYC/K-ras(G12D</span>)-induced lymphomas exhibited sustained regression upon the inactivation of either or both oncogenes.
|
18461184 |
2008 |
|
rs1257715362
|
|
|
0.010 |
GeneticVariation |
BEFREE |
PCR-SSCP and direct DNA sequencing of exons 2 to 14 of p73 revealed a missense mutation in one primary lymphoma: a G-to-A transition, with Glu291Lys change.
|
11461077 |
2001 |
|
rs13181
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To investigate the relationship between DNA repair and NHL we analysed polymorphisms in XPD (R156R, D312N, K751Q) using DNA collected in a UK population-based case-control study of lymphoma.
|
19736055 |
2009 |
|
rs1346044
|
|
|
0.010 |
GeneticVariation |
BEFREE |
WRN Cys1367Arg was associated with decreased risk of NHL overall (OR: 0.71; 95% CI: 0.56-0.91; P=0.007) and DLBCL (OR: 0.66; 95% CI: 0.45-0.95; P=0.024), as well as follicular and marginal zone lymphomas.
|
16738949 |
2006 |
|
rs1351687973
|
|
|
0.010 |
GeneticVariation |
BEFREE |
PCR-SSCP and direct DNA sequencing of exons 2 to 14 of p73 revealed a missense mutation in one primary lymphoma: a G-to-A transition, with Glu291Lys change.
|
11461077 |
2001 |
|
rs1353428252
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The test evaluates the expression of 20 genes, including 17 markers relevant to T-cell immunology and lymphoma biopathology, one EBV-related transcript, and variants of RHOA (G17V) and IDH2 (R172K/T).
|
31488561 |
2019 |
|
rs138228187
|
|
|
0.010 |
GeneticVariation |
BEFREE |
TIRAP p.R81C is a novel lymphoma risk variant which enhances cell proliferation <i>via</i> NF-κB mediated signaling in B-cells.
|
30381301 |
2019 |
|
rs1555525126
|
|
|
0.010 |
GeneticVariation |
BEFREE |
PCR-SSCP and direct DNA sequencing of exons 2 to 14 of p73 revealed a missense mutation in one primary lymphoma: a G-to-A transition, with Glu291Lys change.
|
11461077 |
2001 |
|
rs1695
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Pooled results showed that the GSTT1 null polymorphism might increase the risk of lymphoma (odds ratio [OR] 2.26, 95% confidence interval [CI] 1.20, 4.24; p = 0.01; random-effects model), whereas the impact of GSTM1 and GSTP1 Ile105Val polymorphisms was not significant.
|
22734843 |
2013 |
|
rs17655
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results suggest that the rs1800975, rs17655 and rs1805087 SNPs in DNA repair and synthesis of genes do not seem to play a major role in lymphoma susceptibility.
|
23818366 |
2013 |
|
rs1799793
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To investigate the relationship between DNA repair and NHL we analysed polymorphisms in XPD (R156R, D312N, K751Q) using DNA collected in a UK population-based case-control study of lymphoma.
|
19736055 |
2009 |
|
rs1800871
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Carriage of at least one copy of the T allele for the IL10 rs1800871</span> (as compared to no copies) was associated with decreased AIDS-NHL risk specific to lymphomas arising from the CNS (CC vs. CT/TT: OR = 0.3; 95% CI 0.1, 0.7) but not systemically (CC vs. CT/TT: OR = 1.0; 95% CI 0.5, 1.9) (Pheterogeneity = 0.03).
|
20299965 |
2010 |
|
rs1800890
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Five hundred patients with aggressive NHL treated with CHOP/CHOEP were analyzed for IL-10 gene polymorphisms, including distal loci -7400InDel, -6752AT (rs6676671), and -6208CG (rs10494879) in comparison with proximal loci -3538AT (rs1800890), -1087AG (rs1800896), and -597AC (rs1800872) according to the incidence and outcome of the lymphoma.
|
18559596 |
2008 |
|
rs1800975
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results suggest that the rs1800975, rs17655 and rs1805087 SNPs in DNA repair and synthesis of genes do not seem to play a major role in lymphoma susceptibility.
|
23818366 |
2013 |