|
rs2230926
|
|
|
0.040 |
GeneticVariation |
BEFREE |
A germline and coding polymorphism (rs2230926) of TNFAIP3 (A20), a central gatekeeper of nuclear factor-kappa B (NF-kB) activation, was recently found associated with primary Sjögren's syndrome (pSS)-associated lymphoma in a French cohort.We aimed to replicate this association.
|
26338037 |
2016 |
|
rs2230926
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Increased prevalence of the rs2230926 mutant variant was detected in both SS-lymphoma and SS-nonlymphoma subgroups compared to HC (8.8% vs. 7.6% vs. 3.6%, <i>p</i> values: 0.04 and 0.03, respectively) in association with higher IgM, LDH serum levels, and PB <i>Bcl-XL</i> transcripts but lower leucocyte and neutrophil counts.
|
30662920 |
2018 |
|
rs113488022
|
|
|
0.030 |
GeneticVariation |
BEFREE |
These cases illustrate the expanding spectrum of BRAF V600E-positive histiocytic and dendritic cell tumors and suggest that attention should be paid to lymphomas for possible coincident presentation of these disorders.
|
25787243 |
2015 |
|
rs113488022
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The presence of the BRAF c.1799T>A V600E mutation was recently described in cases of hairy cell leukemia (HCL) but not in other common lymphomas.
|
23161722 |
2012 |
|
rs113488022
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The BRAF-V600E mutation defines genetically hairy cell leukemia among B-cell leukemias and lymphomas.
|
23349307 |
2013 |
|
rs1217691063
|
|
|
0.030 |
GeneticVariation |
BEFREE |
We have previously reported associations between lymphoma risk and germline polymorphisms in genes of methylenetetrahydrofolate reductase (MTHFR C677T and A1298C) and methionine synthase (MTR A2756G), finding the genotype other than the MTHFR 677CC/1298AA to confer a half-risk compared to the MTHFR 677CC/1298AA and a 3-fold higher risk with the MTR GG genotype than the AA/AG genotypes.
|
15551285 |
2004 |
|
rs1217691063
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Αnalysis according to lymphoma subtype revealed increased frequency of c. 677C > T TT genotype and T allele, as well as reduced prevalence of the c. 1298A > C C allele in the pSS non-MALT group compared to controls and patients without NHL.
|
28779180 |
2017 |
|
rs1217691063
|
|
|
0.030 |
GeneticVariation |
BEFREE |
C677T and A1298C methylenetetrahydrofolate reductase (MTHFR) polymorphisms have been suggested to affect susceptibility to malignant lymphoma, possibly by altering DNA methylation.
|
14535593 |
2004 |
|
rs121913377
|
|
|
0.030 |
GeneticVariation |
BEFREE |
These cases illustrate the expanding spectrum of BRAF V600E-positive histiocytic and dendritic cell tumors and suggest that attention should be paid to lymphomas for possible coincident presentation of these disorders.
|
25787243 |
2015 |
|
rs121913377
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The presence of the BRAF c.1799T>A V600E mutation was recently described in cases of hairy cell leukemia (HCL) but not in other common lymphomas.
|
23161722 |
2012 |
|
rs121913377
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The BRAF-V600E mutation defines genetically hairy cell leukemia among B-cell leukemias and lymphomas.
|
23349307 |
2013 |
|
rs1805087
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Herein we performed a case-control study evaluating the influence of three single nucleotide polymorphisms (SNPs) in XPA, ERCC5 and MTR [rs1800975 (G-4A), rs17655 (Asp1104His) and rs1805087 (A2756G), respectively] in lymphoma risk.
|
23818366 |
2013 |
|
rs1805087
|
|
|
0.030 |
GeneticVariation |
BEFREE |
We have previously reported associations between lymphoma risk and germline polymorphisms in genes of methylenetetrahydrofolate reductase (MTHFR C677T and A1298C) and methionine synthase (MTR A2756G), finding the genotype other than the MTHFR 677CC/1298AA to confer a half-risk compared to the MTHFR 677CC/1298AA and a 3-fold higher risk with the MTR GG genotype than the AA/AG genotypes.
|
15551285 |
2004 |
|
rs1805087
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The results in this meta-analysis suggest no association between the MS A2756G polymorphism and lymphoma risk; however, the GG homozygous and G alleles could decrease the lymphoma risk in Caucasians.
|
28742198 |
2017 |
|
rs1805087
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Our results suggest that the rs1800975, rs17655 and rs1805087 SNPs in DNA repair and synthesis of genes do not seem to play a major role in lymphoma susceptibility.
|
23818366 |
2013 |
|
rs1800872
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Five hundred patients with aggressive NHL treated with CHOP/CHOEP were analyzed for IL-10 gene polymorphisms, including distal loci -7400InDel, -6752AT (rs6676671), and -6208CG (rs10494879) in comparison with proximal loci -3538AT (rs1800890), -1087AG (rs1800896), and -597AC (rs1800872) according to the incidence and outcome of the lymphoma.
|
18559596 |
2008 |
|
rs1800872
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Carriage of two copies of the 'low IL10' haplotype rs1800896_A/rs1800871_T/rs1800872_A was associated with decreased lymphoma risk that varied by number of copies (Ptrend = 0.02).
|
20299965 |
2010 |
|
rs1800896
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Five hundred patients with aggressive NHL treated with CHOP/CHOEP were analyzed for IL-10 gene polymorphisms, including distal loci -7400InDel, -6752AT (rs6676671), and -6208CG (rs10494879) in comparison with proximal loci -3538AT (rs1800890), -1087AG (rs1800896), and -597AC (rs1800872) according to the incidence and outcome of the lymphoma.
|
18559596 |
2008 |
|
rs1800896
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Carriage of two copies of the 'low IL10' haplotype rs1800896_A/rs1800871_T/rs1800872_A was associated with decreased lymphoma risk that varied by number of copies (Ptrend = 0.02).
|
20299965 |
2010 |
|
rs25487
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Lack of association between DNA base excision repair gene XRCC1 Gln399Arg polymorphism and risk of malignant lymphoma in Japan.
|
15104288 |
2004 |
|
rs25487
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In this work, we retrospectively evaluated the influence of an XRCC1 polymorphism (rs25487) on the treatment results in a series of 73 patients with lymphoma subjected to ASCT.
|
21463129 |
2011 |
|
rs662
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We have studied the prevalence of three functional polymorphisms affecting these genes rs1051740 EPHX1, rs1800566 NQO1 and rs662 PON1 in 215 patients with lymphoma and 214 healthy controls.
|
23651475 |
2013 |
|
rs662
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In summary, these findings suggested that PON1 Q192R polymorphism was associated with a reduced risk of the overall cancers, nevertheless, it might increase cancer susceptibility of prostate and lymphoma risk.
|
26028114 |
2015 |
|
rs10190751
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A comparison of 183 patients with follicular lymphoma and 233 population controls revealed an increased lymphoma risk associated with the rs10190751 A genotype causing c-FLIP(R) expression.
|
19439735 |
2009 |
|
rs1042522
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Through searching PubMed databases (or hand searching) up to April 2012 using the following MeSH terms and keywords: "p53", "codon 72" "polymorphism" and "leukemia", or "lymphoma", or "myeloma", thirteen were identified as eligible articles in this meta-analysis for p53 Arg72Pro polymorphism (2,731 cases and 7, 356 controls), including nine studies on leukemia (1,266 cases and 4, 474 controls), three studies on lymphoma (1,359 cases and 2,652 controls), and one study on myeloma.
|
23029260 |
2012 |