Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1060501439
rs1060501439
A 0.700 GeneticVariation CLINVAR

dbSNP: rs397516037
rs397516037
A 0.700 CausalMutation CLINVAR

dbSNP: rs768079285
rs768079285
A 0.700 GeneticVariation CLINVAR

dbSNP: rs869312687
rs869312687
G 0.700 CausalMutation CLINVAR

dbSNP: rs4762
rs4762
AGT
0.030 GeneticVariation BEFREE 1.The relationship between the angiotensinogen (AGT) T174M, angiotensin converting enzyme (ACE) insertion/deletion (I/D) and the angiotensin II type 1 receptor (AT1) genetic markers and left ventricular hypertrophy was examined in normal subjects and those with aortic stenosis.2. 8800593

1996

dbSNP: rs699
rs699
AGT
0.060 GeneticVariation BEFREE Angiotensinogen gene M235T polymorphism is associated with the variability in left ventricular hypertrophy induced by endurance training, with athletes homozygous for the T allele having the largest hearts. 10440164

1999

dbSNP: rs1267969615
rs1267969615
ACE
0.050 GeneticVariation BEFREE Angiotensinogen gene M235T polymorphism is associated with the variability in left ventricular hypertrophy induced by endurance training, with athletes homozygous for the T allele having the largest hearts. 10440164

1999

dbSNP: rs699
rs699
AGT
0.060 GeneticVariation BEFREE There are controversies concerning the association of angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism with left ventricular hypertrophy (LVH), and the unclear association between angiotensinogen (ATG) M235T polymorphism and LVH. 10646957

2000

dbSNP: rs1267969615
rs1267969615
ACE
0.050 GeneticVariation BEFREE There are controversies concerning the association of angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism with left ventricular hypertrophy (LVH), and the unclear association between angiotensinogen (ATG) M235T polymorphism and LVH. 10646957

2000

dbSNP: rs699
rs699
AGT
0.060 GeneticVariation BEFREE These results suggest an association of combined angiotensin I-converting enzyme gene I/D polymorphism genotypes, and angiotensinogen gene M235T polymorphism genotypes with left ventricular hypertrophy due to long-term athletic training. 11737220

2001

dbSNP: rs1267969615
rs1267969615
ACE
0.050 GeneticVariation BEFREE These results suggest an association of combined angiotensin I-converting enzyme gene I/D polymorphism genotypes, and angiotensinogen gene M235T polymorphism genotypes with left ventricular hypertrophy due to long-term athletic training. 11737220

2001

dbSNP: rs1415088003
rs1415088003
ACE
0.010 GeneticVariation BEFREE In conclusion, our results suggest an association between LVH and the C825T allele of the G-protein beta3 subunit gene. 11768721

2001

dbSNP: rs699
rs699
AGT
0.060 GeneticVariation BEFREE The angiotensinogen T174M and M235T and the AT1-receptor A1166C polymorphisms were related to the change in LVH during antihypertensive treatment with an AT1-receptor antagonist; of these angiotensinogen T174M was the most powerful. 11910301

2002

dbSNP: rs1267969615
rs1267969615
ACE
0.050 GeneticVariation BEFREE The angiotensinogen T174M and M235T and the AT1-receptor A1166C polymorphisms were related to the change in LVH during antihypertensive treatment with an AT1-receptor antagonist; of these angiotensinogen T174M was the most powerful. 11910301

2002

dbSNP: rs4762
rs4762
AGT
0.030 GeneticVariation BEFREE The angiotensinogen T174M and M235T and the AT1-receptor A1166C polymorphisms were related to the change in LVH during antihypertensive treatment with an AT1-receptor antagonist; of these angiotensinogen T174M was the most powerful. 11910301

2002

dbSNP: rs5443
rs5443
0.030 GeneticVariation BEFREE Lack of association of G-protein subunit gene C825T polymorphism with left ventricular hypertrophy in essential hypertension. 12011775

2002

dbSNP: rs5443
rs5443
0.030 GeneticVariation BEFREE The GNB3 C825T gene polymorphism has recently been identified and associated with hypertension, obesity and left ventricular hypertrophy. 12566975

2003

dbSNP: rs699
rs699
AGT
0.060 GeneticVariation BEFREE Polymorphism of the AGT M235T gene but not ACE I/D gene is associated with greater LVMi and relative wall thickness, indicating more concentric LVH, in Chinese peritoneal dialysis patients. 12675870

2003

dbSNP: rs1267969615
rs1267969615
ACE
0.050 GeneticVariation BEFREE Polymorphism of the AGT M235T gene but not ACE I/D gene is associated with greater LVMi and relative wall thickness, indicating more concentric LVH, in Chinese peritoneal dialysis patients. 12675870

2003

dbSNP: rs5443
rs5443
0.030 GeneticVariation BEFREE GNB3 825 C>T is likely to be a significant risk factor for LVH but not for EH in the Emirati population, thereby strengthening the view that LVH is genetically a separate clinical entity. 15614196

2005

dbSNP: rs699
rs699
AGT
0.060 GeneticVariation BEFREE Angiotensinogen M235T and T174M polymorphisms have individually been associated with elevated levels of plasma angiotensinogen, hypertension, and left ventricular hypertrophy. 17145981

2007

dbSNP: rs4762
rs4762
AGT
0.030 GeneticVariation BEFREE Angiotensinogen M235T and T174M polymorphisms have individually been associated with elevated levels of plasma angiotensinogen, hypertension, and left ventricular hypertrophy. 17145981

2007

dbSNP: rs1042714
rs1042714
0.010 GeneticVariation BEFREE In a prospective follow-up study we screened 970 hypertensive patients of Caucasian descent for the Gly16Arg, Gln27Glu, and Thr164Ile beta(2)AR polymorphisms and left ventricular echocardiographic hypertrophy and assigned selected patients to enalapril or atenolol to assess left ventricular hypertrophy regression after 2-year follow-up. 17178264

2006

dbSNP: rs1178625972
rs1178625972
0.010 GeneticVariation BEFREE In a prospective follow-up study we screened 970 hypertensive patients of Caucasian descent for the Gly16Arg, Gln27Glu, and Thr164Ile beta(2)AR polymorphisms and left ventricular echocardiographic hypertrophy and assigned selected patients to enalapril or atenolol to assess left ventricular hypertrophy regression after 2-year follow-up. 17178264

2006

dbSNP: rs1277204441
rs1277204441
ACE
0.010 GeneticVariation BEFREE In a prospective follow-up study we screened 970 hypertensive patients of Caucasian descent for the Gly16Arg, Gln27Glu, and Thr164Ile beta(2)AR polymorphisms and left ventricular echocardiographic hypertrophy and assigned selected patients to enalapril or atenolol to assess left ventricular hypertrophy regression after 2-year follow-up. 17178264

2006