|
rs1042714
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In a prospective follow-up study we screened 970 hypertensive patients of Caucasian descent for the Gly16Arg, Gln27Glu, and Thr164Ile beta(2)AR polymorphisms and left ventricular echocardiographic hypertrophy and assigned selected patients to enalapril or atenolol to assess left ventricular hypertrophy regression after 2-year follow-up.
|
17178264 |
2006 |
|
rs104894503
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In HCM attributable to the Asp175Asn mutation in the alpha-tropomyosin gene, myocardial oxidative metabolism and FFA metabolism are increased and inversely related to LV hypertrophy at both the whole heart and regional level.
|
17556170 |
2007 |
|
rs104894503
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We studied 140 carriers (G+) of the TPM1-Asp175Asn or MYBPC3-Gln1061X pathogenic variants for HCM: The G+/LVH+ group (n = 98) consisted of mutation carriers with LVH and the G+/LVH- group (n = 42) without LVH.
|
30497761 |
2019 |
|
rs10500279
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Common variants in RYR1 are associated with left ventricular hypertrophy assessed by electrocardiogram.
|
21828061 |
2012 |
|
rs1050606
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the luciferase experiment, ANXA5 rs1050606 had the most promoter activity in myocardial cells (P < .001).These results showed that ANXA5 rs1050606 was significantly associated with LVH in Chinese EH patients, likely via influencing ANXA5 expression in serum and in myocardial cells.
|
29095261 |
2017 |
|
rs1060501439
|
|
A |
0.700 |
GeneticVariation |
CLINVAR |
|
|
|
|
rs11053646
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The genotype frequencies of intron 4 G>A and 3'UTR T>C were not significantly different between the LVH+ and LVH- groups (both P>0.05), however, frequencies of 501G>C were significantly different between those two groups (P=0.007).
|
24480971 |
2014 |
|
rs1137101
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results suggest that the Gln223Arg polymorphism of the leptin receptor is significantly associated with plasma leptin levels and left ventricular hypertrophy in hypertension.
|
24485307 |
2013 |
|
rs11549465
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The distribution differences of gene frequencies for rs11549465, rs11549467 and rs1957757 in HIF1A single nucleotide gene polymorphisms for LVH (+) and LVH (-) were statistically significant (p<0.05).
|
31599436 |
2019 |
|
rs11549467
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The distribution differences of gene frequencies for rs11549465, rs11549467 and rs1957757 in HIF1A single nucleotide gene polymorphisms for LVH (+) and LVH (-) were statistically significant (p<0.05).
|
31599436 |
2019 |
|
rs1178625972
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In a prospective follow-up study we screened 970 hypertensive patients of Caucasian descent for the Gly16Arg, Gln27Glu, and Thr164Ile beta(2)AR polymorphisms and left ventricular echocardiographic hypertrophy and assigned selected patients to enalapril or atenolol to assess left ventricular hypertrophy regression after 2-year follow-up.
|
17178264 |
2006 |
|
rs1217691063
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Sign of these predictive effects is opposite: subjects with MTHFR 677C>T polymorphism have lower likelihood of renal insufficiency; differently, wild-type MTHFR genotype subjects have lower GFR and greater hsCRP, iPTH, RRI, and LVH.
|
23534584 |
2013 |
|
rs121908596
|
|
T |
0.700 |
GeneticVariation |
CLINVAR |
Mutation and phenotypic spectrum in patients with cardio-facio-cutaneous and Costello syndrome.
|
18042262 |
2008 |
|
rs1267969615
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Angiotensinogen gene M235T polymorphism is associated with the variability in left ventricular hypertrophy induced by endurance training, with athletes homozygous for the T allele having the largest hearts.
|
10440164 |
1999 |
|
rs1267969615
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Polymorphism of the AGT M235T gene but not ACE I/D gene is associated with greater LVMi and relative wall thickness, indicating more concentric LVH, in Chinese peritoneal dialysis patients.
|
12675870 |
2003 |
|
rs1267969615
|
|
|
0.050 |
GeneticVariation |
BEFREE |
There are controversies concerning the association of angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism with left ventricular hypertrophy (LVH), and the unclear association between angiotensinogen (ATG) M235T polymorphism and LVH.
|
10646957 |
2000 |
|
rs1267969615
|
|
|
0.050 |
GeneticVariation |
BEFREE |
These results suggest an association of combined angiotensin I-converting enzyme gene I/D polymorphism genotypes, and angiotensinogen gene M235T polymorphism genotypes with left ventricular hypertrophy due to long-term athletic training.
|
11737220 |
2001 |
|
rs1267969615
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The angiotensinogen T174M and M235T and the AT1-receptor A1166C polymorphisms were related to the change in LVH during antihypertensive treatment with an AT1-receptor antagonist; of these angiotensinogen T174M was the most powerful.
|
11910301 |
2002 |
|
rs1277204441
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In a prospective follow-up study we screened 970 hypertensive patients of Caucasian descent for the Gly16Arg, Gln27Glu, and Thr164Ile beta(2)AR polymorphisms and left ventricular echocardiographic hypertrophy and assigned selected patients to enalapril or atenolol to assess left ventricular hypertrophy regression after 2-year follow-up.
|
17178264 |
2006 |
|
rs1333049
|
|
|
0.010 |
GeneticVariation |
BEFREE |
There was no association between rs1333049 genotype and echocardiographic phenotype (left ventricular hypertrophy, systolic dysfunction, diastolic dysfunction, inducible ischemia, exercise capacity, mitral annular calcification, and aortic plaque).
|
19171343 |
2009 |
|
rs1349963459
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of this study was to test the association between a functional polymorphism Glu37Asp (rs2296545) of the renalase gene and left ventricular hypertrophy in a large cohort of patients with aortic stenosis.
|
29065134 |
2017 |
|
rs1415088003
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In conclusion, our results suggest an association between LVH and the C825T allele of the G-protein beta3 subunit gene.
|
11768721 |
2001 |
|
rs142000963
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The c.1930C > T (R644C) missense mutation has previously been reported in eight unrelated patients with variable features including left ventricular hypertrophy, limb girdle muscle weakness, dilated cardiomyopathy and atypical progeria.
|
18478590 |
2008 |
|
rs1436109
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Genetic variation in NCAM1 contributes to left ventricular wall thickness in hypertensive families.
|
21212386 |
2011 |
|
rs148158093
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Fabry disease presenting as apical left ventricular hypertrophy in a patient carrying the missense mutation R118C.
|
24661928 |
2014 |