|
Post-Traumatic Stress Disorder
|
0.020 |
Biomarker
|
disease |
BEFREE |
152 female inbred DBA/2 J mice were submitted to an inescapable footshock paradigm to induce a PTSD-like condition (PTSDLC) and to a paradigm of locomotor sensitization to ethanol.
|
30986492 |
2019 |
|
beta Thalassemia
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
beta thalassemia (beta thal) in DBA/2J mice is a consequence of the spontaneous and complete deletion of the beta major globin gene.
|
8562946 |
1996 |
|
beta^+^ Thalassemia
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
beta thalassemia (beta thal) in DBA/2J mice is a consequence of the spontaneous and complete deletion of the beta major globin gene.
|
8562946 |
1996 |
|
Ductal plate malformation
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
DBA/2J (D2), CD-1, BALB/c and Mus mus castaneus (CAST), express the DPM.
|
10749984 |
2000 |
|
Glaucoma, Open-Angle
|
0.040 |
Biomarker
|
disease |
BEFREE |
DBA/2J (D2) mice develop a form of pigmentary glaucoma involving iris pigment dispersion (IPD) and iris stromal atrophy (ISA).
|
11743578 |
2002 |
|
Liver carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
DBA/2J animals were 3-fold more sensitive to AFB(1)-induced HCC and significantly more sensitive to AFB(1) acute toxicity than were C57BL/6J animals.
|
12907637 |
2003 |
|
Glaucoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
DBA/2J (D2) mice develop an age-related form of glaucoma.
|
16827931 |
2006 |
|
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
DBA/1J mice with CIA that received IL-17-/- donor bone marrow showed potently inhibited development and severity of clinical arthritis as compared with CIA mice that received WT bone marrow.
|
23114425 |
2012 |
|
Diabetic Nephropathy
|
0.040 |
Biomarker
|
disease |
BEFREE |
DBA/2J mice are susceptible to diabetic nephropathy and diabetic exacerbation of IOP elevation.
|
25207540 |
2014 |
|
arthritis symptoms
|
0.010 |
Biomarker
|
disease |
BEFREE |
DBA/1J mice were immunized with chicken type II collagen and then treated intraperitoneally with rhIL-21R-Fc, which was initiated after the onset of arthritis symptoms in 20% of the cohort.
|
25447400 |
2015 |
|
Reflex Epilepsy, Audiogenic
|
0.010 |
Biomarker
|
disease |
BEFREE |
DBA mice exhibit seizure-induced respiratory arrest (S-IRA), leading to cardiac arrest and subsequent sudden death after generalized audiogenic seizures (AGSs).
|
26272185 |
2017 |
|
AICARDI-GOUTIERES SYNDROME
|
0.010 |
Biomarker
|
disease |
BEFREE |
DBA mice exhibit seizure-induced respiratory arrest (S-IRA), leading to cardiac arrest and subsequent sudden death after generalized audiogenic seizures (AGSs).
|
26272185 |
2017 |
|
Intraocular pressure disorder
|
0.100 |
Biomarker
|
disease |
BEFREE |
DBA/2J mice exhibit elevated intraocular pressure, progressive degeneration of their retinal ganglion cells, and optic neuropathy that resembles glaucoma.
|
28540323 |
2017 |
|
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
DBA/1JJmsSlc control mice (n = 5) and DBA/1JJmsSlc collagen-induced arthritis mouse model (arthritis mice; n = 5) were used.
|
28573874 |
2018 |
|
Glaucoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
DBA/2J mice that develop glaucoma with age were also acquired.
|
29294337 |
2018 |
|
Diabetic Nephropathy
|
0.040 |
Biomarker
|
disease |
BEFREE |
DBA/2J mice (a well-characterized model of DKD) and glucose 6-phosphate dehydrogenase (G6PD) deficient mice (a model of impaired antioxidant function) were evaluated.Diabetes was induced by streptozotocin.
|
29979777 |
2018 |
|
Periodontitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
DBA/J1 mouse model of periodontitis with RA was created by local colonization of Porphyromonas gingivalis (Pg) and injection of collagen.
|
31737959 |
2020 |
|
Congenital hypoplastic anemia
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
A 7 year old girl is described with congenital hypoplastic anaemia (Diamond-Blackfan anaemia, DBA) and an apparently balanced reciprocal translocation, 46,XX,t(X;19)(p21;q13).
|
9321770 |
1997 |
|
Post-Traumatic Stress Disorder
|
0.020 |
Biomarker
|
disease |
BEFREE |
A global analysis of the behavioral profile of the two mouse strains based on observed and expected numbers of significant behavioral outcomes indicated that C3HLRI mice showed significantly more often fear- and stress-related PTSD-like behaviors than DBA/2J controls.
|
31805289 |
2020 |
|
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
A mouse model of DBA/1JJmsSlc collagen-induced arthritis was treated with Th2 or Th17 cell inhibitor, and transepidermal water loss (TEWL) and the expression of markers associated with allergic reaction and inflammation were evaluated.
|
30828078 |
2019 |
|
Influenza A
|
0.020 |
Biomarker
|
disease |
BEFREE |
Additionally, an influenza A virus matrix 2 protein-based antigen displayed on these rOMVs resulted in 100% survival against a lethal challenge with two influenza A virus strains (H1N1 and H3N2) in mice with different genetic backgrounds (BALB/c, C57BL/6, and DBA/2J).
|
28215994 |
2017 |
|
Down Syndrome
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
After adjusting for confounders (age, level of ID, history of falls, comorbidities and number of non-DBI medications, Down syndrome (grip strength only) and gender (timed up and go and Barthel Index)), neither grip strength nor timed up and go were significantly associated with DBI, DBA or DBS score > 0 (p > 0.05).
|
31234775 |
2019 |
|
Complete Trisomy 21 Syndrome
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
After adjusting for confounders (age, level of ID, history of falls, comorbidities and number of non-DBI medications, Down syndrome (grip strength only) and gender (timed up and go and Barthel Index)), neither grip strength nor timed up and go were significantly associated with DBI, DBA or DBS score > 0 (p > 0.05).
|
31234775 |
2019 |
|
Arthritis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Alpha-mangostin: Anti-inflammatory and antioxidant effects on established collagen-induced arthritis in DBA/1J mice.
|
30557668 |
2019 |
|
Dermatologic disorders
|
0.010 |
Biomarker
|
group |
BEFREE |
Although IMQ-induced expression shifts mirrored psoriasis, responses in BALB/c, 129/SvJ, DBA, and MOLF mice were more consistent with other human skin conditions (e.g., wounds or infections).
|
28279190 |
2017 |