|
Acute myocardial infarction
|
0.080 |
Biomarker
|
disease |
BEFREE |
Serum adiponectin in both groups and salivary adiponectin in patients with AMI decreased with increasing body mass index.
|
27549083 |
2017 |
|
Acute myocardial infarction
|
0.080 |
AlteredExpression
|
disease |
BEFREE |
The present results support the hypothesis that high rather than low levels of adiponectin predict mortality after acute myocardial infarction.
|
28185529 |
2017 |
|
Acute myocardial infarction
|
0.080 |
Biomarker
|
disease |
BEFREE |
Previous studies suggested that adiponectin (APN) could ameliorate ischemia/reperfusion injury and endothelial dysfunction in patients with acute myocardial infarction.
|
30779470 |
2019 |
|
Acute myocardial infarction
|
0.080 |
Biomarker
|
disease |
BEFREE |
We confirmed that the plasma sP‑selectin levels were increased in patients with obesity (particularly pericardial obesity) and hyperlipidemia, positively correlated with plasma tumor necrosis factor (TNF)‑α and strongly negatively correlated with adiponectin in all patients regardless of AMI status.
|
25384966 |
2015 |
|
Acute myocardial infarction
|
0.080 |
Biomarker
|
disease |
BEFREE |
The mechanism of exogenous adiponectin in the prevention of no-reflow phenomenon in type 2 diabetic patients with acute myocardial infarction during PCI treatment.
|
29687877 |
2018 |
|
Acute myocardial infarction
|
0.080 |
Biomarker
|
disease |
BEFREE |
The most informative biochemical parameters associated with the development of diabetes at 1 year after MI were adiponectin, retinol protein, ghrelin, tumor necrosis factor α, and plasminogen activator inhibitor.
|
28261283 |
2017 |
|
Acute myocardial infarction
|
0.080 |
Biomarker
|
disease |
BEFREE |
Administration of intracoronary adiponectin could be a useful adjunctive therapy for acute myocardial infarction.
|
20332381 |
2010 |
|
Acute myocardial infarction
|
0.080 |
Biomarker
|
disease |
BEFREE |
To investigate the correlations of acute myocardial infarction (AMI) complicated by cerebral infarction with insulin resistance, adiponectin and high-mobility group box 1 (HMGB1).
|
31173318 |
2019 |
|
Acute pancreatitis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Low serum adiponectin levels are associated with systemic organ failure in acute pancreatitis.
|
19696691 |
2009 |
|
Acute respiratory distress
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Adiponectin gene polymorphisms and acute respiratory distress syndrome susceptibility and mortality.
|
24586568 |
2014 |
|
Adenocarcinoma
|
0.020 |
AlteredExpression
|
group |
BEFREE |
We characterized the expressions of adiponectin and several of its downstream targets in paired samples of tumor tissue and adjacent noncancerous mucosa in 60 surgical patients with colorectal adenocarcinomas.
|
24636346 |
2014 |
|
Adenocarcinoma
|
0.020 |
Biomarker
|
group |
LHGDN |
Globular adiponectin, acting via adiponectin receptor-1, inhibits leptin-stimulated oesophageal adenocarcinoma cell proliferation.
|
18313838 |
2008 |
|
Adenocarcinoma Of Esophagus
|
0.020 |
Biomarker
|
disease |
BEFREE |
Anti-inflammatory effect of full-length adiponectin and proinflammatory effect of globular adiponectin in esophageal adenocarcinoma cells.
|
24330848 |
2013 |
|
Adenocarcinoma Of Esophagus
|
0.020 |
Biomarker
|
disease |
BEFREE |
Adiponectin inhibited leptin-induced Akt phosphorylation; this action was sensitive to okadaic acid but not to Compound C. Adiponectin deficiency may contribute to the promotion of OAC in obesity.
|
18313838 |
2008 |
|
Adenocarcinoma of large intestine
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
To assess IGFBP-6 expression in relation with the presence of the metabolic syndrome, adiponectin receptors (AdipoR1 and AdipoR2) and IGF-IR levels in colorectal adenocarcinoma cases.
|
27644646 |
2016 |
|
Adenocarcinoma of lung (disorder)
|
0.020 |
Biomarker
|
disease |
BEFREE |
In the present study, we investigated the effects of different concentrations of Acrp30 on the A549 human alveolar epithelial cell line, an in vitro model of lung adenocarcinoma.
|
30654148 |
2019 |
|
Adenocarcinoma of lung (disorder)
|
0.020 |
Biomarker
|
disease |
BEFREE |
we analyzed cell proliferation, cell cycle of A549 cells treated with adiponectin as well as CREB activation status in human lung adenocarcinoma A549 cells and in non-small cell lung cancer (NSCLC) samples.
|
28506662 |
2017 |
|
Adenocarcinoma of prostate
|
0.010 |
Biomarker
|
disease |
BEFREE |
To test the hypothesis that adiponectin exerts direct antiproliferative and/or pro-apoptotic effects on cancer cells, we used the PC-3 human prostate adenocarcinoma cell line.
|
24793551 |
2014 |
|
Adenocarcinoma of rectum
|
0.010 |
Biomarker
|
disease |
BEFREE |
Adipokine levels were higher in women.Controls had higher leptin (32.±4.34 vs 9.51±1.73 ng/ml in women and 11±2.66 vs 2.54±0.39 ng/ml in men, p = 0.00048 and 0.0032) and lower adiponectin (9±0.64 vs 11.85±1.02 μg/ml in women and 7.39±0.51 vs 8.5±0.62 μg/ml in men, p = 0.017 and 0.019) than RC patients.
|
31425509 |
2019 |
|
Adenocarcinoma, Endometrioid
|
0.010 |
Biomarker
|
disease |
BEFREE |
In adiponectin receptor-positive endometrioid adenocarcinoma, we think adiponectin-based anticancer therapy is useful; however, in histological high-grade endometrioid adenocarcinoma, in which the expression levels of adiponectin receptors are relatively low, adiponectin therapy supported by adiponectin receptor induction is needed.
|
22653349 |
2012 |
|
Adenoma
|
0.030 |
GeneticVariation
|
group |
BEFREE |
At rs1201299 in ADIPOQ, the AC genotype had a higher risk (OR 1.58, 95%CI 1.00-2.49) of adenomas, while the minor AA genotype had a borderline inverse association (OR 0.44, 95%CI 0.18-1.08; reference: CC).
|
29802748 |
2018 |
|
Adenoma
|
0.030 |
AlteredExpression
|
group |
BEFREE |
Immunohistochemical staining demonstrated that adiponectin was expressed in spindle-shaped cells of the subepithelial layer in normal colon tissues, whereas ill-defined overexpression of adiponectin was seen in the stroma of advanced adenoma and CRC tissues.
|
25370174 |
2014 |
|
Adenoma
|
0.030 |
AlteredExpression
|
group |
BEFREE |
Adiponectin receptor expression in the human adrenal cortex and aldosterone-producing adenomas.
|
16685404 |
2006 |
|
Adenomatous Polyps
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Mean insulin, leptin and adiponectin receptor expression levels were lower in adenomatous polyp samples in comparison with normal and tumour tissue.
|
22193626 |
2012 |
|
Adiponectin Deficiency
|
0.370 |
GeneticVariation
|
disease |
BEFREE |
Whole-cell patch-clamp recordings in brain slices revealed that intrinsic excitability of DG granule neurons was enhanced by adiponectin deficiency and suppressed after treatment with the adiponectin mimetic AdipoRon, which were associated with increased input resistance and hyperpolarized resting membrane potential, respectively.
|
27137743 |
2017 |