|
Adiponectin Deficiency
|
0.370 |
Biomarker
|
disease |
CTD_human |
|
|
|
|
Adiponectin Deficiency
|
0.370 |
AlteredExpression
|
disease |
BEFREE |
In this study, in order to determine whether adiponectin affects tumor growth and tumor induced vascularization, we implanted B16F10 melanoma and Lewis Lung Carcinoma cells subcutaneously into adiponectin knockout and wild-type control mice, and found that adiponectin deficiency markedly promoted the growth of both tumors.
|
20700533 |
2010 |
|
Adiponectin Deficiency
|
0.370 |
AlteredExpression
|
disease |
BEFREE |
Adiponectin overexpression also promoted apoptotic cell clearance and reduced features of autoimmunity in lpr mice whereas adiponectin deficiency in lpr mice led to a further reduction in apoptotic cell clearance, which was accompanied by exacerbated systemic inflammation.
|
17256056 |
2007 |
|
Adiponectin Deficiency
|
0.370 |
Biomarker
|
disease |
BEFREE |
The present study provides evidence that adiponectin is a protective regulator in the development and progression of BPH and that adiponectin deficiency causally links BPH with obesity.
|
28256562 |
2017 |
|
Adiponectin Deficiency
|
0.370 |
Biomarker
|
disease |
BEFREE |
Exogenous recombinant adiponectin specifically dampened airway chitin-mediated eosinophil recruitment, while adiponectin deficiency resulted in increased airway eosinophils.
|
31134096 |
2019 |
|
Adiponectin Deficiency
|
0.370 |
Biomarker
|
disease |
BEFREE |
This study aims to develop adiponectin secreting genetically modified MSCs (GM-MSCs) as a potent strategic tool to complement endogenous adiponectin for the treatment of adiponectin deficiency diseases.
|
28606849 |
2017 |
|
Adiponectin Deficiency
|
0.370 |
Biomarker
|
disease |
BEFREE |
To investigate the causal role of hypoadiponectinemia in GDM, adiponectin gene knockout (<i>Adipoq<sup>-/-</sup></i> ) and wild-type (WT) mice were crossed to produce pregnant mouse models with or without adiponectin deficiency.
|
28073830 |
2017 |
|
Adiponectin Measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genome-wide linkage and association analyses to identify genes influencing adiponectin levels: the GEMS Study.
|
19165155 |
2009 |
|
Adiponectin Measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Adiponectin concentrations: a genome-wide association study.
|
20887962 |
2010 |
|
Adiponectin Measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Connecting genetic risk to disease end points through the human blood plasma proteome.
|
28240269 |
2017 |
|
Adiponectin Measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals.
|
20018283 |
2010 |
|
Adiponectin Measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Genome-wide linkage and association analyses to identify genes influencing adiponectin levels: the GEMS Study.
|
19165155 |
2009 |
|
Adiponectin Measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.
|
22479202 |
2012 |
|
Adiponectin Measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.
|
22479202 |
2012 |
|
Adiponectin Measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals.
|
20018283 |
2010 |
|
ADIPONECTIN, SERUM LEVEL OF, QUANTITATIVE TRAIT LOCUS 1
|
0.300 |
GeneticVariation
|
phenotype |
UNIPROT |
Genomic structure and mutations in adipose-specific gene, adiponectin.
|
10918532 |
2000 |
|
ADIPONECTIN, SERUM LEVEL OF, QUANTITATIVE TRAIT LOCUS 2
|
0.300 |
Biomarker
|
phenotype |
CTD_human |
The genetic basis of plasma variation in adiponectin, a global endophenotype for obesity and the metabolic syndrome.
|
11549668 |
2001 |
|
ADIPONECTIN, SERUM LEVEL OF, QUANTITATIVE TRAIT LOCUS 3
|
0.300 |
Biomarker
|
phenotype |
CTD_human |
The genetic basis of plasma variation in adiponectin, a global endophenotype for obesity and the metabolic syndrome.
|
11549668 |
2001 |
|
Adolescent idiopathic scoliosis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Asymmetric expression of H19 and ADIPOQ in concave/convex paravertebral muscles is associated with severe adolescent idiopathic scoliosis.
|
30241458 |
2018 |
|
Adolescent Obesity
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
This study was conducted to evaluate the role of suPAR, and its association with leptin, adiponectin, interleukin-6 (IL-6), high-sensitive C-reactive protein (hsCRP) and fibrinogen in adolescent obesity.
|
28749394 |
2017 |
|
Adrenal Gland Neoplasms
|
0.010 |
AlteredExpression
|
group |
BEFREE |
We evaluated RT-PCR of leptin and adiponectin mRNA expression from the adipose tissue surrounding adrenal glands in 30 patients, collecting adipose tissue surrounding the adrenal neoplasms, peri-renal and subcutaneous depots.
|
25313911 |
2015 |
|
Adrenal Gland Pheochromocytoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
AdpR1 mRNA expression was significantly associated with the tumor tissue adrenaline content (p<0.005) in linear regression analysis, which suggest that adrenaline positively regulates AdpR1 mRNA expression.Serum total and HMW Adp levels in patients with NA-type pheochromocytomas were approximately 3 times higher than those of healthy volunteers.
|
19672024 |
2009 |
|
Adrenal incidentaloma
|
0.020 |
Biomarker
|
disease |
BEFREE |
Moreover patients with AI and TC or TT genotype have significantly lower serum adiponectin which may be an early symptom of metabolic syndrome in patients with AI.
|
21979884 |
2011 |
|
Adrenal incidentaloma
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
The eNOS, ACE, TNF-alpha, transforming growth factor (TGF)-beta genes polymorphisms, TNF-alpha, adiponectin levels were analysed in 50 unrelated Turkish patients with a diagnosis of adrenal incidentaloma (AI).
|
19498318 |
2009 |
|
Adult Acute Lymphocytic Leukemia
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
The majority of the studies indicated that leptin levels are increased and adiponectin levels are decreased in ALL children at diagnosis, as well as in ALL survivors.
|
30696312 |
2019 |