Source: BEFREE

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5078
Gene Symbol: PAX4
PAX4 		paired box 4 0.644 0.423 4.2E-04
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 1.000 limited 0.857 19 3 1999 2019
Entrez Id: 5506
Gene Symbol: PPP1R3A
PPP1R3A 		protein phosphatase 1 regulatory subunit 3A 0.711 0.577 9.3E-16
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 1.000 limited 0.929 13 1 1994 2018
Entrez Id: 5167
Gene Symbol: ENPP1
ENPP1 		ectonucleotide pyrophosphatase/phosphodiesterase 1 0.498 0.808 5.0E-08
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.700 moderate 0.814 58 8 2000 2019
Entrez Id: 2645
Gene Symbol: GCK
GCK 		glucokinase 0.523 0.808 0.63
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.900 strong 0.953 178 5 1992 2020
Entrez Id: 6927
Gene Symbol: HNF1A
HNF1A 		HNF1 homeobox A 0.478 0.846 0.96
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.900 strong 0.954 117 17 1995 2019
Entrez Id: 3767
Gene Symbol: KCNJ11
KCNJ11 		potassium inwardly rectifying channel subfamily J member 11 0.529 0.615 1.1E-02
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.900 strong 0.943 91 11 1996 2019
Entrez Id: 7466
Gene Symbol: WFS1
WFS1 		wolframin ER transmembrane glycoprotein 0.528 0.846 1.6E-38
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.700 strong 0.974 29 9 2002 2020
Entrez Id: 4760
Gene Symbol: NEUROD1
NEUROD1 		neuronal differentiation 1 0.543 0.808 0.77
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.800 strong 0.920 21 2 1999 2018
Entrez Id: 2641
Gene Symbol: GCG
GCG 		glucagon 0.431 0.885 3.5E-02
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.400 None 0.990 580 2 1986 2020
Entrez Id: 6524
Gene Symbol: SLC5A2
SLC5A2 		solute carrier family 5 member 2 0.499 0.769 4.9E-14
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.100 None 0.977 488 3 2005 2020
Entrez Id: 1803
Gene Symbol: DPP4
DPP4 		dipeptidyl peptidase 4 0.420 0.808 7.3E-09
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.100 None 0.979 487 2 2005 2020
Entrez Id: 2740
Gene Symbol: GLP1R
GLP1R 		glucagon like peptide 1 receptor 0.471 0.846 0.29
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.500 None 0.978 448 5 1993 2020
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2 		transcription factor 7 like 2 0.485 0.846 1.00
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.700 None 0.965 367 26 2006 2020
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ 		adiponectin, C1Q and collagen domain containing 0.376 0.885 4.6E-09
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.600 None 0.950 338 23 1999 2020
Entrez Id: 79813
Gene Symbol: EHMT1
EHMT1 		euchromatic histone lysine methyltransferase 1 0.460 0.808 1.00
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.100 None 0.970 298 3 1993 2020
Entrez Id: 5468
Gene Symbol: PPARG
PPARG 		peroxisome proliferator activated receptor gamma 0.358 0.885 2.9E-02
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.700 None 0.953 262 11 1998 2020
Entrez Id: 3375
Gene Symbol: IAPP
IAPP 		islet amyloid polypeptide 0.507 0.808 3.2E-03
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.400 None 0.958 204 1 1989 2020
Entrez Id: 100125288
Gene Symbol: ZGLP1
ZGLP1 		zinc finger GATA like protein 1 0.512 0.808 0.39
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.100 None 0.985 202 0 1993 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF 		tumor necrosis factor 0.231 0.962 0.80
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.600 None 0.950 176 7 1995 2020
Entrez Id: 1636
Gene Symbol: ACE
ACE 		angiotensin I converting enzyme 0.328 0.923 1.0E-37
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.100 None 0.921 163 8 1994 2020
Entrez Id: 3172
Gene Symbol: HNF4A
HNF4A 		hepatocyte nuclear factor 4 alpha 0.461 0.808 0.15
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 1.000 None 0.942 142 25 1992 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6 		interleukin 6 0.248 0.962 0.32
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.300 None 0.951 142 4 1993 2020
Entrez Id: 1401
Gene Symbol: CRP
CRP 		C-reactive protein 0.299 0.962 3.7E-03
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.100 None 0.969 127 3 2002 2020
Entrez Id: 3643
Gene Symbol: INSR
INSR 		insulin receptor 0.432 0.846 3.6E-05
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.700 None 0.962 127 5 1985 2020
Entrez Id: 3667
Gene Symbol: IRS1
IRS1 		insulin receptor substrate 1 0.488 0.769 2.4E-02
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		disease 0.900 None 0.939 126 7 1993 2019