×
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
Malignant neoplasm of oropharynx
0.100
Biomarker
BEFREE
The study subset with OPC and known p16 status was mainly from Australasia, Western Europe, and North America.
27209505 2017
×
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
Malignant neoplasm of oropharynx
0.100
Biomarker
BEFREE
The pretreatment QOL/PS scores were correlated with outcome and p16 status in patients with oropharyngeal cancer (OPC ).
27727066 2017
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Malignant neoplasm of oropharynx
0.100
Biomarker
BEFREE
We sought to investigate the pathology and rates of HPV head and neck oropharyngeal cancer in Japan via p16 immunohistochemistry at 2 institutions in Japan.
27913709 2017
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Malignant neoplasm of oropharynx
0.100
Biomarker
BEFREE
The pretreatment QOL/PS scores were correlated with outcome and p16 status in patients with oropharyngeal cancer (OPC ).
27727066 2017
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Malignant neoplasm of oropharynx
0.100
Biomarker
BEFREE
The study subset with OPC and known p16 status was mainly from Australasia, Western Europe, and North America.
27209505 2017
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Malignant neoplasm of oropharynx
0.100
Biomarker
BEFREE
Immunohistochemistry for p16 is established as a surrogate marker of human papillomavirus (HPV) in oropharyngeal cancer . p16 expression in HNcSCC needs to be elucidated to determine its utility in predicting the primary site.
28663082 2017
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Malignant neoplasm of oropharynx
0.100
GeneticVariation
BEFREE
Patients with p53 mutant OSCC had significantly worse overall survival (p=0.01).
26952933 2016
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Malignant neoplasm of oropharynx
0.100
AlteredExpression
BEFREE
Impact of p16 expression in oropharyngeal cancer in the postoperative setting: the necessity of re-evaluating traditional risk stratification.
27474125 2016
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Malignant neoplasm of oropharynx
0.100
AlteredExpression
BEFREE
No benefit for regional control and survival by planned neck dissection in primary irradiated oropharyngeal cancer irrespective of p16 expression.
26059208 2016
×
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
Malignant neoplasm of oropharynx
0.100
AlteredExpression
BEFREE
No benefit for regional control and survival by planned neck dissection in primary irradiated oropharyngeal cancer irrespective of p16 expression.
26059208 2016
×
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
Malignant neoplasm of oropharynx
0.100
AlteredExpression
BEFREE
Impact of p16 expression in oropharyngeal cancer in the postoperative setting: the necessity of re-evaluating traditional risk stratification.
27474125 2016
×
Entrez Id: 3749
Gene Symbol: KCNC4
KCNC4
Malignant neoplasm of oropharynx
0.100
GeneticVariation
GWASCAT
Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer.
27749845 2016
×
Entrez Id: 23001
Gene Symbol: WDFY3
WDFY3
Malignant neoplasm of oropharynx
0.100
GeneticVariation
GWASCAT
Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer.
27749845 2016
×
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
Malignant neoplasm of oropharynx
0.100
Biomarker
BEFREE
The diagnosis of HPV-related oropharyngeal cancer in clinical practice is based on p16 immunohistochemistry and PCR detection of viral DNA (HPV-PCR).
25687724 2015
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Malignant neoplasm of oropharynx
0.100
GeneticVariation
BEFREE
Overall, this study provides evidence of epigenetic changes to the downstream region of the CDKN2A locus in HPV+ oropharyngeal cancer that are associated with changes in expression of the coded protein products.
25619363 2015
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Malignant neoplasm of oropharynx
0.100
Biomarker
BEFREE
Population-based p16 and HPV positivity rates in oropharyngeal cancer in Southeast Scotland.
26152733 2015
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Malignant neoplasm of oropharynx
0.100
Biomarker
BEFREE
The diagnosis of HPV-related oropharyngeal cancer in clinical practice is based on p16 immunohistochemistry and PCR detection of viral DNA (HPV-PCR).
25687724 2015
×
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
Malignant neoplasm of oropharynx
0.100
Biomarker
BEFREE
Population-based p16 and HPV positivity rates in oropharyngeal cancer in Southeast Scotland.
26152733 2015
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Malignant neoplasm of oropharynx
0.100
Biomarker
BEFREE
Among these biomarkers, p53 is the strongest prognostic marker in OPC and p53 in addition to p16 support the rationale to study of de-escalation strategy for OPC .
25380690 2014
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Malignant neoplasm of oropharynx
0.100
Biomarker
BEFREE
Our findings show that p16 IHC alone has potential as a prognostic test for oropharyngeal cancer survival, but combined p16/HPV testing is necessary to identify HPV-associated nonoropharyngeal HNSCC with better prognosis.
24706381 2014
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Malignant neoplasm of oropharynx
0.100
Biomarker
BEFREE
Significant correlations were confirmed between p16 positivity and oropharyngeal cancer , MMP1 and p16 positivity, and recurrence and smoking.
25503184 2014
×
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
Malignant neoplasm of oropharynx
0.100
Biomarker
BEFREE
Among these biomarkers, p53 is the strongest prognostic marker in OPC and p53 in addition to p16 support the rationale to study of de-escalation strategy for OPC .
25380690 2014
×
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
Malignant neoplasm of oropharynx
0.100
Biomarker
BEFREE
Significant correlations were confirmed between p16 positivity and oropharyngeal cancer , MMP1 and p16 positivity, and recurrence and smoking.
25503184 2014
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Malignant neoplasm of oropharynx
0.100
Biomarker
BEFREE
Among these biomarkers, p53 is the strongest prognostic marker in OPC and p53 in addition to p16 support the rationale to study of de-escalation strategy for OPC .
25380690 2014
×
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
Malignant neoplasm of oropharynx
0.100
AlteredExpression
BEFREE
Large data on HPV DNA detection by PCR and p16 expression in HNC biopsies suggests that the probability of a cancer of the oral cavity, larynx, and hypopharynx being attributable to HPV is at least 5-fold lower than that for oropharyngeal cancer .
24331868 2014