Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.400 0.880 27 0 1993 2017
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 412 0.417 0.759 1.00 0.370 1.000 9 0 1999 2016
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor nucleic acid binding; transcription factor 499 0.382 0.724 1.00 0.370 1.000 9 0 1996 2017
Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10
P50591 TNF superfamily member 10 signaling molecule 295 0.440 0.828 0.13 0.370 1.000 8 0 2004 2015
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 891 0.321 0.828 0.38 0.360 1.000 8 0 1996 2016
Entrez Id: 7015
Gene Symbol: TERT
TERT
O14746 telomerase reverse transcriptase nucleic acid binding 541 0.393 0.828 1.00 0.360 1.000 7 1 2006 2017
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 nucleic acid binding; transcription factor 706 0.358 0.862 1.00 0.360 1.000 7 0 2003 2018
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor signaling molecule 1640 0.263 0.966 0.80 0.360 1.000 7 0 2004 2016
Entrez Id: 9971
Gene Symbol: NR1H4
NR1H4
Q96RI1 nuclear receptor subfamily 1 group H member 4 nucleic acid binding; receptor; transcription factor 149 0.522 0.655 1.3E-03 0.350 1.000 9 0 2012 2017
Entrez Id: 27232
Gene Symbol: GNMT
GNMT
Q14749 glycine N-methyltransferase 46 0.642 0.345 1.4E-02 0.340 1.000 5 0 1998 2011
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
P01135 transforming growth factor alpha signaling molecule 290 0.447 0.724 0.74 0.340 1.000 5 0 1996 2011
Entrez Id: 3082
Gene Symbol: HGF
HGF
P14210 hepatocyte growth factor hydrolase; protease 478 0.394 0.793 1.00 0.340 1.000 5 0 1995 2014
Entrez Id: 3481
Gene Symbol: IGF2
IGF2
P01344 insulin like growth factor 2 505 0.399 0.828 4.7E-02 0.340 1.000 5 0 1988 2003
Entrez Id: 196
Gene Symbol: AHR
AHR
P35869 aryl hydrocarbon receptor receptor; transcription factor 276 0.462 0.862 1.00 0.330 1.000 4 0 2003 2014
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
metastasis associated lung adenocarcinoma transcript 1 129 0.519 0.724 0.330 1.000 4 0 2013 2016
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 enzyme modulator 589 0.365 0.828 0.90 0.330 1.000 4 0 2007 2016
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha kinase; transferase 835 0.341 0.897 1.00 0.330 1.000 4 1 2005 2014
Entrez Id: 3439
Gene Symbol: IFNA1
IFNA1
P01562 interferon alpha 1 405 0.403 0.828 0.330 1.000 4 0 2004 2009
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
P37231 peroxisome proliferator activated receptor gamma nucleic acid binding; receptor; transcription factor 540 0.388 0.828 0.14 0.330 1.000 4 0 2006 2015
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase enzyme modulator 545 0.404 0.828 8.7E-02 0.320 1.000 7 0 2000 2008
Entrez Id: 5894
Gene Symbol: RAF1
RAF1
P04049 Raf-1 proto-oncogene, serine/threonine kinase 328 0.462 0.793 0.89 0.320 1.000 3 0 2008 2015
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
P49789 fragile histidine triad 277 0.450 0.828 2.9E-02 0.320 1.000 3 0 1998 2002
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 nucleic acid binding; receptor; transcription factor 686 0.355 0.897 1.00 0.320 1.000 3 0 2003 2017
Entrez Id: 5465
Gene Symbol: PPARA
PPARA
Q07869 peroxisome proliferator activated receptor alpha nucleic acid binding; receptor; transcription factor 247 0.465 0.793 3.7E-02 0.320 1.000 3 0 1999 2016
Entrez Id: 407021
Gene Symbol: MIR29A
MIR29A
microRNA 29a 131 0.523 0.690 0.320 1.000 2 0 2011 2012