DisGeNET - a database of gene-disease associations

Juvenile arthritis, C3495559

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs12046117

VTCN1

0.800

GeneticVariation

GWASDB

Identification of a novel susceptibility locus for juvenile idiopathic arthritis by genome-wide association analysis.

19116933

2009

dbSNP:

rs12046117

VTCN1

0.800

GeneticVariation

GWASCAT

Identification of a novel susceptibility locus for juvenile idiopathic arthritis by genome-wide association analysis.

19116933

2009

dbSNP:

rs2395148

TSBP1 ; TSBP1-AS1

0.800

GeneticVariation

GWASCAT

Association of the TRAF1-C5 locus on chromosome 9 with juvenile idiopathic arthritis.

18576341

2008

dbSNP:

rs2395148

TSBP1 ; TSBP1-AS1

0.800

GeneticVariation

GWASDB

Association of the TRAF1-C5 locus on chromosome 9 with juvenile idiopathic arthritis.

18576341

2008

dbSNP:

rs10761744

JMJD1C

0.700

GeneticVariation

GWASDB

Genome-wide association analysis of juvenile idiopathic arthritis identifies a new susceptibility locus at chromosomal region 3q13.

22354554

2012

dbSNP:

rs10761745

JMJD1C

0.700

GeneticVariation

GWASDB

Genome-wide association analysis of juvenile idiopathic arthritis identifies a new susceptibility locus at chromosomal region 3q13.

22354554

2012

dbSNP:

rs11817689

0.700

GeneticVariation

GWASDB

Genome-wide association analysis of juvenile idiopathic arthritis identifies a new susceptibility locus at chromosomal region 3q13.

22354554

2012

dbSNP:

rs12002949

LOC102723803

0.700

GeneticVariation

GWASDB

Genome-wide association analysis of juvenile idiopathic arthritis identifies a new susceptibility locus at chromosomal region 3q13.

22354554

2012

dbSNP:

rs12416113

NRBF2

0.700

GeneticVariation

GWASDB

Genome-wide association analysis of juvenile idiopathic arthritis identifies a new susceptibility locus at chromosomal region 3q13.

22354554

2012

dbSNP:

rs16918575

REEP3

0.700

GeneticVariation

GWASDB

Genome-wide association analysis of juvenile idiopathic arthritis identifies a new susceptibility locus at chromosomal region 3q13.

22354554

2012

dbSNP:

rs16939895

PTPN2

0.700

GeneticVariation

GWASDB

Genome-wide association analysis of juvenile idiopathic arthritis identifies a new susceptibility locus at chromosomal region 3q13.

22354554

2012

dbSNP:

rs2542151

0.700

GeneticVariation

GWASDB

Genome-wide association analysis of juvenile idiopathic arthritis identifies a new susceptibility locus at chromosomal region 3q13.

22354554

2012

dbSNP:

rs2893922

JMJD1C

0.700

GeneticVariation

GWASDB

Genome-wide association analysis of juvenile idiopathic arthritis identifies a new susceptibility locus at chromosomal region 3q13.

22354554

2012

dbSNP:

rs4746201

REEP3

0.700

GeneticVariation

GWASDB

Genome-wide association analysis of juvenile idiopathic arthritis identifies a new susceptibility locus at chromosomal region 3q13.

22354554

2012

dbSNP:

rs7082090

JMJD1C

0.700

GeneticVariation

GWASDB

Genome-wide association analysis of juvenile idiopathic arthritis identifies a new susceptibility locus at chromosomal region 3q13.

22354554

2012

dbSNP:

rs7234029

PTPN2

0.700

GeneticVariation

GWASDB

Genome-wide association analysis of juvenile idiopathic arthritis identifies a new susceptibility locus at chromosomal region 3q13.

22354554

2012

dbSNP:

rs9414780

JMJD1C

0.700

GeneticVariation

GWASDB

Genome-wide association analysis of juvenile idiopathic arthritis identifies a new susceptibility locus at chromosomal region 3q13.

22354554

2012

dbSNP:

rs9414788

JMJD1C

0.700

GeneticVariation

GWASDB

Genome-wide association analysis of juvenile idiopathic arthritis identifies a new susceptibility locus at chromosomal region 3q13.

22354554

2012

dbSNP:

rs9415699

JMJD1C

0.700

GeneticVariation

GWASDB

Genome-wide association analysis of juvenile idiopathic arthritis identifies a new susceptibility locus at chromosomal region 3q13.

22354554

2012

dbSNP:

rs9415705

JMJD1C

0.700

GeneticVariation

GWASDB

Genome-wide association analysis of juvenile idiopathic arthritis identifies a new susceptibility locus at chromosomal region 3q13.

22354554

2012

dbSNP:

rs2476601

PTPN22 ; AP4B1-AS1

0.090

GeneticVariation

BEFREE

The association between rs2476601 and JIA appears restricted to females, partly accounting for the predominance of females with this disease.

26291515

2015

dbSNP:

rs2476601

PTPN22 ; AP4B1-AS1

0.090

GeneticVariation

BEFREE

This meta-analysis showed the association between the T-allele and the T/T genotype and JIA (OR = 1.34, P = 0.03; OR = 1.97, P = 0.02) but did not reveal the association between the PTPN22 C1858T polymorphism and IBD, psoriasis, multiple sclerosis, Addison's disease and Celiac disease.

16760194

2007

dbSNP:

rs2476601

PTPN22 ; AP4B1-AS1

0.090

GeneticVariation

BEFREE

Association analysis of the 1858C>T polymorphism in the PTPN22 gene in juvenile idiopathic arthritis and other autoimmune diseases.

15759012

2005

dbSNP:

rs2476601

PTPN22 ; AP4B1-AS1

0.090

GeneticVariation

BEFREE

Its +1858C>T (R620W) polymorphism has been shown to associate with a risk for multiple autoimmune diseases, including type 1 diabetes (T1D) and juvenile idiopathic arthritis (JIA).

17000021

2007

dbSNP:

rs2476601

PTPN22 ; AP4B1-AS1

0.090

GeneticVariation

BEFREE

Associations of STAT4 rs7574865 G/T and PTPN22 (rs2488457 G/C and rs2476601 C/T) polymorphisms with JIA have repeatedly been replicated in several Caucasian populations.

25781893

2015