|
rs1018981
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SNPs at rs1018981 and rs10931481 were correlated with higher risk of polyarticular JIA.
|
30620272 |
2019 |
|
rs10931481
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SNPs at rs1018981 and rs10931481 were correlated with higher risk of polyarticular JIA.
|
30620272 |
2019 |
|
rs11893432
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The G allele of rs11893432 was significantly associated with JIA risk, particularly oligoarticular JIA, in Han Chinese populations.
|
30620272 |
2019 |
|
rs2228570
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of this study was to evaluate the influence of rs2228570 polymorphism on lipid profile and on outcome in patients with juvenile idiopathic arthritis (JIA) treated with etanercept.
|
30128913 |
2019 |
|
rs10954213
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Allele and genotype frequencies of the rs10954213 and rs3807306 did not show any significant difference between JIA and control group.
|
29423720 |
2018 |
|
rs11466018
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We report evolution of PR to juvenile idiopathic arthritis in a Japanese girl with heterozygous complex L110P-E148Q allele of MEFV gene.
|
26457478 |
2018 |
|
rs17435
|
|
|
0.010 |
GeneticVariation |
BEFREE |
MECP2 gene rs17435 polymorphism was associated with JIA predisposition.
|
29288368 |
2018 |
|
rs1801133
|
|
|
0.010 |
GeneticVariation |
BEFREE |
C677T (rs1801133) polymorphism in MTHFR predicts nonresponse and/or adverse effects of MTX treatment in JIA patients.
|
29589488 |
2018 |
|
rs3743930
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We report evolution of PR to juvenile idiopathic arthritis in a Japanese girl with heterozygous complex L110P-E148Q allele of MEFV gene.
|
26457478 |
2018 |
|
rs3807306
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Allele and genotype frequencies of the rs10954213 and rs3807306 did not show any significant difference between JIA and control group.
|
29423720 |
2018 |
|
rs10919563
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the present study, we analyzed three single nucleotide polymorphisms (SNPs), namely PTPRC (rs10919563), TYK2 (rs34536443) and PRKCQ (rs4750316), which were found to be associated with JIA in previous studies.
|
28990043 |
2017 |
|
rs2240337
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The A allele at rs2240</span>337 was a significant risk factor for ACPA positivity in JIA (OR = 5.6, 95% CI = 1.71-23.7 pc = 0.03).
|
28182665 |
2017 |
|
rs34536443
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the present study, we analyzed three single nucleotide polymorphisms (SNPs), namely PTPRC (rs10919563), TYK2 (rs34536443) and PRKCQ (rs4750316), which were found to be associated with JIA in previous studies.
|
28990043 |
2017 |
|
rs4750316
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the present study, we analyzed three single nucleotide polymorphisms (SNPs), namely PTPRC (rs10919563), TYK2 (rs34536443) and PRKCQ (rs4750316), which were found to be associated with JIA in previous studies.
|
28990043 |
2017 |
|
rs1004819
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The only association was seen between rs1004819 and polyarticular JIA.
|
26016922 |
2016 |
|
rs1003706636
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Statistically significant difference in genotype frequency for Thr399Ile SNP of TLR4 was observed in the jSpA (χ2 = 6.705, p = 0.035) and not in the JIA group (χ2 = 3005, p = 0.223).
|
25920454 |
2015 |
|
rs10431961
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two SNPs were also associated with JIA, and we found evidence of interaction such that methylation was only associated with JIA in minor allele carriers (e.g. rs10431961 p(interaction) = 0.011).
|
26057774 |
2015 |
|
rs1127354
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These preliminary results indicate that genotyping of ATIC rs2372536 and ITPA rs1127354 variants or measuring ITPA activity could be useful to predict methotrexate response in children with JIA after validation by further prospective studies on a larger patient cohort.
|
25240429 |
2015 |
|
rs1980422
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We identified two novel associations with oligoarticular and RF-negative polyarticular JIA: CD226 rs763361 (OR 1.30, 95% CI 1.12 to 1.51, p=0.0006) and CD28 rs1980422</span> (OR 1.29, 95% CI 1.07 to 1.55, p=0.008).
|
25057181 |
2015 |
|
rs2372536
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These preliminary results indicate that genotyping of ATIC rs2372536 and ITPA rs1127354 variants or measuring ITPA activity could be useful to predict methotrexate response in children with JIA after validation by further prospective studies on a larger patient cohort.
|
25240429 |
2015 |
|
rs2488457
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our data strengthen STAT4 rs7574865 G/T and PTPN22 rs2488457 G/C polymorphisms as susceptibility factors for JIA.
|
25781893 |
2015 |
|
rs2501432
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To investigate whether the functional variant Q63R of the cannabinoid 2 (CB2) receptor is associated with susceptibility to oligo/poly-articular juvenile idiopathic arthritis (JIA) and with its clinical features.
|
25974389 |
2015 |
|
rs35761398
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A significant difference in genotype distribution of the CB2 Q63R variant (CNR2 rs35761398) between oligo/poly-articular JIA patients and controls was found (p = 0.001).
|
25974389 |
2015 |
|
rs35829419
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our aim was to determine whether SNP of TLR2 (Arg753Gln), TLR4 (Asp299Gly, Thr399Ile), and NLRP3 (Q705K) influence susceptibility to juvenile spondyloarthrtis (jSpA) and juvenile idiopathic arthritis (JIA).
|
25920454 |
2015 |
|
rs5743708
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our aim was to determine whether SNP of TLR2 (Arg753Gln), TLR4 (Asp299Gly, Thr399Ile), and NLRP3 (Q705K) influence susceptibility to juvenile spondyloarthrtis (jSpA) and juvenile idiopathic arthritis (JIA).
|
25920454 |
2015 |