Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1003706636
rs1003706636
NLRP3
0.010 GeneticVariation BEFREE Statistically significant difference in genotype frequency for Thr399Ile SNP of TLR4 was observed in the jSpA (χ2 = 6.705, p = 0.035) and not in the JIA group (χ2 = 3005, p = 0.223). 25920454

2015
dbSNP: rs1004819
rs1004819
IL23R ; C1orf141
0.010 GeneticVariation BEFREE The only association was seen between rs1004819 and polyarticular JIA. 26016922

2016
dbSNP: rs10128264
rs10128264
ZMIZ1
C 0.700 GeneticVariation GWASCAT Genome-wide data reveal novel genes for methotrexate response in a large cohort of juvenile idiopathic arthritis cases. 24709693

2014
dbSNP: rs1018981
rs1018981
LOC105375246
0.010 GeneticVariation BEFREE SNPs at rs1018981 and rs10931481 were correlated with higher risk of polyarticular JIA. 30620272

2019
dbSNP: rs1042713
rs1042713
ADRB2
0.010 GeneticVariation BEFREE Genotypes and haplotypes of two ADRB2 variants (G16R and Q27E) were determined in 348 children with JIA and 448 healthy controls by direct molecular haplotyping using melting-curve analysis of a fluorescently labelled loci-spanning probe. 19177262

2009
dbSNP: rs1042714
rs1042714
ADRB2
0.010 GeneticVariation BEFREE Genotypes and haplotypes of two ADRB2 variants (G16R and Q27E) were determined in 348 children with JIA and 448 healthy controls by direct molecular haplotyping using melting-curve analysis of a fluorescently labelled loci-spanning probe. 19177262

2009
dbSNP: rs10431961
rs10431961
MMP25
0.010 GeneticVariation BEFREE Two SNPs were also associated with JIA, and we found evidence of interaction such that methylation was only associated with JIA in minor allele carriers (e.g. rs10431961 p(interaction) = 0.011). 26057774

2015
dbSNP: rs10499194
rs10499194 		0.010 GeneticVariation BEFREE The strongest associations with JIA risk or protection were observed for TNFAIP3 variants rs10499194 (OR 0.74 [95% CI 0.61-0.91], P < 0.004) and rs6920220 (OR 1.30 [95% CI 1.05-1.61], P = 0.015). 19565500

2009
dbSNP: rs1051266
rs1051266
SLC19A1
0.010 GeneticVariation BEFREE ABCB1 rs1045642, ABCC3 rs4793665, and SLC19A1 rs1051266 polymorphisms were associated with response to MTX in 287 patients with JIA studied longitudinally. 22859359

2012
dbSNP: rs10761744
rs10761744
JMJD1C
0.700 GeneticVariation GWASDB Genome-wide association analysis of juvenile idiopathic arthritis identifies a new susceptibility locus at chromosomal region 3q13. 22354554

2012
dbSNP: rs10761745
rs10761745
JMJD1C
0.700 GeneticVariation GWASDB Genome-wide association analysis of juvenile idiopathic arthritis identifies a new susceptibility locus at chromosomal region 3q13. 22354554

2012
dbSNP: rs10822050
rs10822050 		C 0.700 GeneticVariation GWASCAT Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. 26301688

2015
dbSNP: rs10919563
rs10919563
PTPRC
0.010 GeneticVariation BEFREE In the present study, we analyzed three single nucleotide polymorphisms (SNPs), namely PTPRC (rs10919563), TYK2 (rs34536443) and PRKCQ (rs4750316), which were found to be associated with JIA in previous studies. 28990043

2017
dbSNP: rs10931481
rs10931481
STAT4
0.010 GeneticVariation BEFREE SNPs at rs1018981 and rs10931481 were correlated with higher risk of polyarticular JIA. 30620272

2019
dbSNP: rs10954213
rs10954213
IRF5
0.010 GeneticVariation BEFREE Allele and genotype frequencies of the rs10954213 and rs3807306 did not show any significant difference between JIA and control group. 29423720

2018
dbSNP: rs10956445
rs10956445
CCDC26
C 0.700 GeneticVariation GWASCAT Genome-wide data reveal novel genes for methotrexate response in a large cohort of juvenile idiopathic arthritis cases. 24709693

2014
dbSNP: rs10988542
rs10988542
FNBP1
C 0.700 GeneticVariation GWASCAT Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. 26301688

2015
dbSNP: rs11145763
rs11145763
CARD9
C 0.700 GeneticVariation GWASCAT Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. 26301688

2015
dbSNP: rs11209026
rs11209026
IL23R
0.010 GeneticVariation BEFREE Single nucleotide polymorphisms (SNPs) in ERAP1 (rs30187) and IL23R (rs11209026) were genotyped in JIA cases (n = 1,054) and healthy controls (n = 5,200). 21281511

2011
dbSNP: rs11225055
rs11225055
ANGPTL5
C 0.700 GeneticVariation GWASCAT Genome-wide data reveal novel genes for methotrexate response in a large cohort of juvenile idiopathic arthritis cases. 24709693

2014
dbSNP: rs1127354
rs1127354
ITPA
0.010 GeneticVariation BEFREE These preliminary results indicate that genotyping of ATIC rs2372536 and ITPA rs1127354 variants or measuring ITPA activity could be useful to predict methotrexate response in children with JIA after validation by further prospective studies on a larger patient cohort. 25240429

2015
dbSNP: rs11466018
rs11466018
MEFV
0.010 GeneticVariation BEFREE We report evolution of PR to juvenile idiopathic arthritis in a Japanese girl with heterozygous complex L110P-E148Q allele of MEFV gene. 26457478

2018
dbSNP: rs114846446
rs114846446
LINC01250
A 0.700 GeneticVariation GWASCAT Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. 26301688

2015
dbSNP: rs11580078
rs11580078
IL23R ; C1orf141
G 0.700 GeneticVariation GWASCAT Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. 26301688

2015
dbSNP: rs117372389
rs117372389
NKD1
T 0.700 GeneticVariation GWASCAT Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. 26301688

2015