|
Acquired Immunodeficiency Syndrome
|
0.010 |
GeneticVariation
|
group |
BEFREE |
The patients with ARC and AIDS had a highly significant decrease in CR1-E when compared with normal individuals (p = less than 0.001) and studies of families of 4 AIDS patients suggest that this defect is acquired.
|
2938642 |
1986 |
|
Acute glomerulonephritis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
In our earlier study we have shown that there is a decreased expression of CR1 on the erythrocytes of patients with acute glomerulonephritis.
|
8080606 |
1993 |
|
Acute GVH disease
|
0.020 |
Biomarker
|
disease |
BEFREE |
T cells deficient in C3a receptor (C3aR) and/or C5a receptor (C5aR) responded weakly in allogeneic hosts and exhibited limited ability to induce GvHD.
|
22585573 |
2012 |
|
Acute GVH disease
|
0.020 |
Biomarker
|
disease |
BEFREE |
Finally, experimental induction of GvHD in complement C3-deficient mice confirms the link between Gp96 and complement C3 in the serum and with the severity of the disease.
|
28352659 |
2017 |
|
Acute kidney injury
|
0.400 |
Biomarker
|
disease |
CTD_human |
A Multiplatform Approach for the Discovery of Novel Drug-Induced Kidney Injury Biomarkers.
|
28885000 |
2017 |
|
Acute kidney injury
|
0.400 |
Biomarker
|
disease |
HPO |
|
|
|
|
Acute Kidney Insufficiency
|
0.300 |
Biomarker
|
disease |
CTD_human |
A Multiplatform Approach for the Discovery of Novel Drug-Induced Kidney Injury Biomarkers.
|
28885000 |
2017 |
|
Acute Lung Injury
|
0.200 |
Therapeutic
|
disease |
RGD |
"Beneficial effect of the polysaccharides from Bupleurum smithii var. parvifolium on ""two-hit"" acute lung injury in rats."
|
22763771 |
2012 |
|
Acute lymphocytic leukemia
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
ASP and ATIII activity was measured in 76 children with ALL treated according to the ALL IC BFM 2002 protocol.
|
28060110 |
2017 |
|
Acute lymphocytic leukemia
|
0.060 |
GeneticVariation
|
disease |
BEFREE |
Patients with GRIA1 rs4958351 AA/AG genotype showed significantly reduced risk to ASP hypersensitivity compared to patients with GG genotype in the T-cell ALL subgroup (OR = 0.05 (0.01-0.26); p = 4.70E-04), while no such association was found in pre-B-cell ALL.
|
26457809 |
2015 |
|
Acute lymphocytic leukemia
|
0.060 |
Biomarker
|
disease |
BEFREE |
Asparaginase (ASP) is a cornerstone in the treatment of acute lymphoblastic leukemia (ALL).
|
28440015 |
2017 |
|
Acute lymphocytic leukemia
|
0.060 |
Biomarker
|
disease |
BEFREE |
The aim of the present study was to investigate the growth inhibition effects of GA in combination with asparaginase (ASP), as a component of combination chemotherapy, in a lymphoblastic leukemia cell line.
|
29217160 |
2017 |
|
Acute lymphocytic leukemia
|
0.060 |
GeneticVariation
|
disease |
BEFREE |
Thrombotic events (TEs) are serious secondary complications in children with acute lymphoblastic leukemia (ALL) who receive L-asparaginase (ASP) therapy; however, the prevalence of TEs has not been established.
|
12518376 |
2003 |
|
Acute lymphocytic leukemia
|
0.060 |
Biomarker
|
disease |
BEFREE |
Native vs. PEG-ASP administered according to availability in each center were prospectively evaluated in adults with high-risk ALL.
|
29165013 |
2018 |
|
Acute myocardial infarction
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The results of immunoblotting suggested that the protein expression of C3a receptor in infarct tissues of patients with acute myocardial infarction was significantly higher than that of normal tissues adjacent to the infarcted area (P<0.05).
|
28962185 |
2017 |
|
Adenocarcinoma Of Esophagus
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Similar chimeric transcripts encoding portions of the MET oncogene and the BCAS3 gene also were overexpressed in EAs, suggesting that L1-5'ASP activation may occur at a broad level in primary EAs.
|
16320248 |
2006 |
|
Adenoma
|
0.010 |
AlteredExpression
|
group |
BEFREE |
Detection of complement C3 and factor B gene expression in normal colorectal mucosa, adenomas and carcinomas.
|
9528886 |
1998 |
|
Adult Acute Lymphocytic Leukemia
|
0.040 |
Biomarker
|
disease |
BEFREE |
Asparaginase (ASP) is a cornerstone in the treatment of acute lymphoblastic leukemia (ALL).
|
28440015 |
2017 |
|
Adult Acute Lymphocytic Leukemia
|
0.040 |
GeneticVariation
|
disease |
BEFREE |
Thrombotic events (TEs) are serious secondary complications in children with acute lymphoblastic leukemia (ALL) who receive L-asparaginase (ASP) therapy; however, the prevalence of TEs has not been established.
|
12518376 |
2003 |
|
Adult Acute Lymphocytic Leukemia
|
0.040 |
AlteredExpression
|
disease |
BEFREE |
ASP and ATIII activity was measured in 76 children with ALL treated according to the ALL IC BFM 2002 protocol.
|
28060110 |
2017 |
|
Adult Acute Lymphocytic Leukemia
|
0.040 |
Biomarker
|
disease |
BEFREE |
Native vs. PEG-ASP administered according to availability in each center were prospectively evaluated in adults with high-risk ALL.
|
29165013 |
2018 |
|
Adult Medulloblastoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Flow cytometry and Western blot were performed on three established medulloblastoma lines and one surgically-procured cell culture to determine expression of C3a receptor (C3aR) in medulloblastoma.
|
25603857 |
2015 |
|
Adverse reaction to drug
|
0.300 |
Biomarker
|
group |
CTD_human |
A Multiplatform Approach for the Discovery of Novel Drug-Induced Kidney Injury Biomarkers.
|
28885000 |
2017 |
|
Age related macular degeneration
|
0.700 |
Biomarker
|
disease |
CTD_human |
Variation in complement factor 3 is associated with risk of age-related macular degeneration.
|
17767156 |
2007 |
|
Age related macular degeneration
|
0.700 |
GeneticVariation
|
disease |
GWASDB |
Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC).
|
20385826 |
2010 |